Left Ventricular Reverse Remodeling after Surgical Aortic Valve Replacement for Aortic Regurgitation—An Explorative Study
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Population
2.2. Echocardiographic Assessment
2.3. Study Endpoints
2.4. Statistical Analysis
3. Results
3.1. Procedural Outcome
3.2. Early Hemodynamics
3.3. Mid-Term Clinical Outcome
3.4. Left Ventricular Reverse Remodeling
4. Discussion
5. Conclusions
6. Limitations
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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n = 25 | |
---|---|
Age (years), mean ± SD (range) | 59 ± 16.3 (29–79) |
Male | 20 (80%) |
Diagnosis | |
Chronic aortic regurgitation | 23 (92%) |
Acute aortic dissection | 1 (4%) |
Infective endocarditis | 1 (4%) |
Bicuspid aortic valve | 8 (32%) |
NYHA functional class | |
I–II | 11 (44%) |
III–IV | 14 (56%) |
Comorbidities | |
Hypertension | 14 (56%) |
Dyslipidemia | 14 (56%) |
COPD | 6 (24%) |
Diabetes mellitus | 1 (4%) |
Obesity (BMI > 30) | 4 (16%) |
Renal impairment 1 | 10 (40%) |
Previous cardiac surgery | 1 (4%) |
EuroSCORE II mean ± SD (range), % | 3.06 ± 5.00 (0.56–24.28) |
LVEF ± SD (range), % | 45.1 ± 8.01 (20–55) |
n = 25 | |
---|---|
Concomitant procedures | 17 (68%) |
Isolated AVR | 3 (12%) |
Aortic root enlargement | 3 (12%) |
Root/ascending ± partial arch repair | 2 (8%) |
PFO closure | |
Valve prosthesis model | |
Mechanic | 6 (24%) |
SJM Regent | 3 (12%) |
ATS | 2 (8%) |
ON-X | 1 (4%) |
Stented bovine | 18 (72%) |
Edwards Perimount Magna | 13 (52%) |
SJM Trifecta | 5 (20%) |
Stented porcine Medtronic Hancock II | 1 (4%) |
Valve size | |
21 mm | 2 (8%) |
23 mm | 3 (12%) |
25 mm | 9 (36%) |
27 mm | 11 (44%) |
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Arnold, Z.; Elnekheli, A.; Geisler, D.; Aschacher, T.; Lenz, V.; Winkler, B.; Moidl, R.; Grabenwöger, M. Left Ventricular Reverse Remodeling after Surgical Aortic Valve Replacement for Aortic Regurgitation—An Explorative Study. Diseases 2024, 12, 191. https://doi.org/10.3390/diseases12080191
Arnold Z, Elnekheli A, Geisler D, Aschacher T, Lenz V, Winkler B, Moidl R, Grabenwöger M. Left Ventricular Reverse Remodeling after Surgical Aortic Valve Replacement for Aortic Regurgitation—An Explorative Study. Diseases. 2024; 12(8):191. https://doi.org/10.3390/diseases12080191
Chicago/Turabian StyleArnold, Zsuzsanna, Alexander Elnekheli, Daniela Geisler, Thomas Aschacher, Verena Lenz, Bernhard Winkler, Reinhard Moidl, and Martin Grabenwöger. 2024. "Left Ventricular Reverse Remodeling after Surgical Aortic Valve Replacement for Aortic Regurgitation—An Explorative Study" Diseases 12, no. 8: 191. https://doi.org/10.3390/diseases12080191