In this section, a simulation study is conducted to compare the performance of the different point and intervals estimates. Further, a simulated dataset is investigated for illustration purposes.
6.1. Simulation Study
For illustration, we conduct a simulation study of a competing risks model with specified competing risk distribution under the progressive censoring to numerically estimate the model parameters. The competing risks data are simulated using the cause-specific hazard driven approach by Beyersmann [
22] when
are assumed to be
. To compare the performance of parameter estimates, we choose the bias, mean square error (MSE) for point estimates, the interval length (IL) and coverage probability (CP) for interval estimates. We generated
competing risks datasets under progressive censoring. For each simulated dataset, we determine
bootstrap samples and
samples, and the first 25% portion of MCMC samples as burn-in times within the Gibbs–MH algorithm. Denote
n as the number of identical items.
For the
l-th simulated dataset for
, the maximum likelihood estimates of the parameters can be obtained by solving the likelihood equations in Equations (
10) and (
11), and the Bayes estimates of parameters can be calculated using the steps of the MH algorithm in
Section 5. We then get the estimates of reliability characteristics
and
given
t and the interval estimates based on the parameter estimates. For simplicity, we denote the estimate of a parameter or a reliability characteristic as
. The point estimate and interval estimate of
using the
l-th simulated dataset are given as
and
, respectively. The indicator function is defined as
Thus, the performance measures are of the following forms:
We choose , surviving items discarded under the progressive censoring scheme and three specific schemes as follow:
- Scheme 1:
.
- Scheme 2:
.
- Scheme 3:
, and the others for .
In the schemes above, and are randomly selected from the set .
Under the assumptions of bivariate competing failure causes and APE distribution, the procedures to generate the competing risks data under the progressive censoring scheme are given as follows:
- 1.
Generate the uniform progressive censoring data
by specified scheme
using the sampling algorithm in Balakrishnan and Sandhu [
23].
- 2.
Compute the roots
of the equations
where
is the survival function of the competing risks random variable
given in Equation (
3).
- 3.
Simulate binomial samples with probability on failure cause 1, and probability on failure cause 2.
In Bayesian inference, independent gamma priors are often chosen for the model parameter. To determine the hyper-parameters of Gamma prior distribution, for simplicity we assume the scale parameters are equal to 1, and the MLEs
are the expectations of prior distributions. Therefore, the priors are given as
Under the setting above, we obtain the MLEs and BEs of unknown parameters for
and the three schemes in
Table 1,
Table 2 and
Table 3, and the ACIs, PBCI and SBCIs and the HPD-credible intervals of unknown parameters are given in
Table 4,
Table 5 and
Table 6.
- 1.
The MSEs of MLEs and BEs decrease with the increasing samples n under the three schemes. However, the MSEs of shape parameters are larger than scale parameters for the maximum likelihood method and the Bayes method, and the scale parameters have smaller MSEs and absolute Bias using the Bayes method than the maximum likelihood method. Under Scheme 1, the MSEs of MLEs are smaller than BEs. This indicates that the progressive censoring schemes have a small influence on the performance of point estimates.
- 2.
The biases of scale parameters and are negative except for the MLEs for under Scheme 2. For Bayes estimation, the scale parameters are underestimated in all cases. The shape parameters and are overestimated using the maximum likelihood method and Bayes method. This shows that the parameter role, i.e., shape and scale parameters in the competing risks model considering the APE distribution, has an impact on the estimation.
- 1.
The ILs of ACIs, PBCIs, SBCIs and HPD-credible intervals decrease when n increases under all schemes. This implies that the progressive censoring schemes have little influence on the performance of ILs.
- 2.
The coverage probabilities of the mentioned confidence intervals show that the shape parameters are covered in the confidence intervals under all the schemes and specified sample sizes. This does not hold for coverage probabilities of the scale parameters. However, the CPs of HPD-credible intervals for scale parameters are close to the nominal probability when n is increasing under Schemes 1 and 2.
- 3.
In terms of ILs, SBCIs and HPD-credible intervals are better than ACIs and PBCIs. For the coverage probabilities, bootstrap methods perform better than the other two interval estimation methods.
We also present the point estimates (MLEs and BEs) and interval estimates (ACIs, PBCIs, SBCIs and HPD-credible intervals) of
and
at given point
x under the three schemes. Here, we choose
to show the performance of estimation for reliability characteristics. The MLEs and BEs of
and
are given in
Table 7 for Scheme 1,
Table 8 for Scheme 2 and
Table 9 for Scheme 3. The interval estimates of
and
are given in
Table 10 for Scheme 1,
Table 11 for Scheme 2 and
Table 12 for Scheme 3.
- 1.
The MSEs of MLEs of and at decrease with the increasing samples n under the three schemes. However, the MSEs of BEs have small changes with increasing n when RF and HRF are estimated.
- 2.
R(x) is underestimated using maximum likelihood and Bayes methods, and is overestimated under the specified schemes. This indicates that the progressive censoring schemes have little influence on the performance of MLES.
- 3.
In
Table 10,
Table 11 and
Table 12, the ILs of ACIs, PBCIs, SBCIs and HPD-credible interval estimates for
and
decrease when
n increases under all schemes. Further,
and
are always covered in ACIs, but they have the largest interval lengths. The progressive schemes have little influence on ACIs, but they have an influence on the other intervals.
- 4.
In terms of ILs and CPs, PBCIs and HPD-credible intervals are better than ACIs and SBCIs for all the schemes.
We also note that, from the coverage probabilities of interval estimation of parameters and reliability characteristics, it can be found that the coverage probabilities are 1 in most cases for ACIs and PBCIs, which are conducted based on the maximum likelihood method. Compared with SBCIs and HPD-credible intervals in terms of the occurrance of coverage probabilities equal to 1, this indicates that SBCIs and HPD-credible intervals perform better than ACIs and PBCIs. In our simulation study, the interval estimates
of
obtained using the estimation procedures in
Section 3,
Section 4 and
Section 5 lie in the range
. It is noted that the asymptotic confidence interval of
may be outside of
. In this case, transformation on
could be applied to avoid the occurrence of exceeding the range
. On the other hand, though the simulated results for the interval estimates of
and
are the subsets of the domains of reliability characteristics, the transformation approach could also be suggested to improve the performance of interval estimation.
To summarize, based on the MSEs, ILs and CPs of parameter estimates, the performance is relatively good and stable when for Scheme 1.
6.2. Numerical Example
In the simulation study, we discuss the performance of the competing risks model parameter estimates comparing the maximum likelihood method, bootstrap method and Bayes method considering the APE distribution with
. The numerical results above show the performance of parameter estimates is affected by the schemes. For an illustration of the reliability estimates, here we choose the setting of
and Scheme 1 because the parameter estimates perform well under this setting, as mentioned above. The generated dataset of competing risks data under progressive censoring of Scheme 1 is presented in
Table 13.
For the dataset in
Table 13, 92 observations with 8 units censored in Scheme 3 are listed where 29 samples are from competing risk
, and the other 63 samples are from competing risk
. The parameter estimates are given in
Table 14. In this table, ACI-IL indicates the ILs of interval estimates for ACIs. This is similar to PBCI-IL, SBCI-IL and HPD-IL-credible intervals. From the numerical estimates, HPD-credible intervals and PBCIs have smaller ILs than ACIs and SBCIs.
Figure 1 shows the log-likelihood functions of
, which reveals that the MLEs exist and are unique. Moreover, to show the convergence of MCMC iterations, the trace plots are presented in
Figure 2.
Further, using the MLEs, bootstrap samples and MCMC, we can compute the estimates of the reliability and hazard rate given a specified argument
x in Equations (
5) and (
6). For the continuous argument
x, we present the curves of the MLEs and BEs in
Figure 3, and ranges of ACIs using the delta method, bootstrap confidence intervals (PBCIs and SBCIs) and HPD-credible intervals in
Figure 4 and
Figure 5.
We see from
Figure 3a that the estimates of
are close to the true values of RF. This implies that the maximum likelihood and Bayes methods are effective and applicable to evaluate RF in the competing risks model with a progressive censoring scheme when the lifetime distribution of the individual is the APE distribution. We also see that BE is higher than the true values but MLE is lower than the true values. In
Figure 3b, the MLE numerical errors between the estimated HRF and the true HRF are higher than the estimated RF when
x is increasing. The BEs are lower than the true values, and a crossing point occurs between the BEs and the true values. We also find that the errors become larger when
x is increasing, and, meanwhile, the MLEs perform better than BEs.
For the interval estimation of
in
Figure 4, we find that PBCI, SBCI and HPD-credible intervals perform better than ACI, where ACI has a larger IL. The subtle differences among the PBCI, SBCI and HPD-credible intervals are that the lower limits of PBCI and SBCI and the upper limits of the HPD-credible intervals are closer to the true values. The interval estimates are asymmetric for the Bayes and bootstrap methods. As shown in
Figure 5, we see that ACI has the largest errors in hazard rate estimates among the four interval estimate methods, while PBCI has the smallest error. That is, the Bayes and bootstrap methods are better than ACI in terms of the ILs. When
x is increasing, the Bayes method has closer lower limits than bootstrap estimates.
In this numerical example, we focus on the comparison of estimates for RF and HRF. We suggest percentile bootstrap and Bayes methods for interval estimation of and . Considering the sampling complexity and time-consuming features of MCMC, the maximum likelihood method is a good choice for point estimation.