Myxoid Liposarcomas of the Thigh: Pre-Operative Presentation, Clinical Outcomes, and Functional Results of Surgical Treatment
Abstract
:1. Introduction
2. Materials and Methods
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Low-Grade (n = 20) | High-Grade (n = 10) | Total Population (n = 30) | p (<0.05) | |
---|---|---|---|---|
Number | 20 | 10 | 30 | - |
Mean Age (min–max) | 45.5 (17–71) | 56.7 (25–77) | 49.2 (17–77) | - |
Gender Female Male | 11 9 | 2 8 | 13 17 | - |
Average Diagnostic Interval (min–max) | 7.7 (1–16) | 7.5 (1–60) | 7.6 (1–60) | |
Localization Anterior Compartment Medial Compartment Posterior Compartment | 7 6 7 | 5 2 3 | 12 8 10 | - |
Mean Size (min–max) | 11.2 cm (5–18) | 13.2 cm (5–23) | 11.9 cm (5–23) | - |
Pre-Op Swelling (percentage) | 20 (100%) | 10 (100%) | 30 (100%) | - |
Pre-Op Pain (percentage) | 2 (10%) | 0 | 2 (7%) | - |
Mean Pre-Op MSTS Score (min–max) | 26.0 (15–29) | 25.2 (15–29) | 25.8 (15–29) | - |
Pre-Op Radiotherapy (percentage) | 0 | 8 (80%) | 9 (27%) | - |
Margins Wide Marginal | 16 4 | 8 2 | 24 6 | - |
Intra-Op Complications | 0 | 0 | 0 | - |
Post-Op Complications (percentage) Seroma Infection Dehiscence Dysesthesia | 4 (20%) 1 1 1 1 | 2 (20%) 1 1 0 0 | 6 (20%) 2 2 1 1 | - |
Post-Op Radiotherapy (percentage) | 3 (15%) | 0 | 3 (10%) | - |
Local Recurrences (percentage) | 4 (20%) | 1 (10%) | 5 (15%) | FISHER’S EXACT TEST: Contingency between low grade and local recurrence (p = 0.041) |
Metastases (percentage) | 0 | 3 (33%) | 3 (10%) | FISHER’S EXACT TEST: Contingency between high-grade lesions and metastases (p = 0.031) |
Oncological Outcomes CDF (percentage) DOC (percentage) NED (percentage) AWD (percentage) DOD (percentage) | 15 (75%) 0 3 (15%) 1 (5%) 1 (5%) | 5 (50%) 1 (10%) 2 (20%) 1 (10%) 1 (10%) | 21 (70%) 1 (3%) 5 (17%) 2 (7%) 1 (3%) | - |
Mean Post-Op MSTS Score (min–max) | 26.7 (15–30) | 27.6 (25–30) | 27.0 (15–30) | - |
Follow-Up (min–max) | 60.4 months (21–89) | 53.5 months (20–72) | 58.1 months (20–89) | - |
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Ipponi, E.; Bechini, E.; Cordoni, M.; Gentili, F.; Cosseddu, F.; D’Arienzo, A.; Andreani, L. Myxoid Liposarcomas of the Thigh: Pre-Operative Presentation, Clinical Outcomes, and Functional Results of Surgical Treatment. Healthcare 2024, 12, 1718. https://doi.org/10.3390/healthcare12171718
Ipponi E, Bechini E, Cordoni M, Gentili F, Cosseddu F, D’Arienzo A, Andreani L. Myxoid Liposarcomas of the Thigh: Pre-Operative Presentation, Clinical Outcomes, and Functional Results of Surgical Treatment. Healthcare. 2024; 12(17):1718. https://doi.org/10.3390/healthcare12171718
Chicago/Turabian StyleIpponi, Edoardo, Elena Bechini, Martina Cordoni, Fabrizia Gentili, Fabio Cosseddu, Antonio D’Arienzo, and Lorenzo Andreani. 2024. "Myxoid Liposarcomas of the Thigh: Pre-Operative Presentation, Clinical Outcomes, and Functional Results of Surgical Treatment" Healthcare 12, no. 17: 1718. https://doi.org/10.3390/healthcare12171718