Post-Operative All-Cause Mortality in Elderly Patients Undergoing Abdominal Emergency Surgery: Role of Charlson Comorbidity Index
Abstract
:1. Introduction
2. Materials and Methods
2.1. Population and Administrative Data Source
2.2. Charlson Comorbidity Index (CCI) Calculation
2.3. Statistical Analysis
3. Results
4. Discussion
Limitations
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Survivors | Deceased | p | |
---|---|---|---|
(n = 150) | (n = 47) | ||
Age (years) | 77.4 ± 6.4 | 81.5 ± 7.7 | <0.01 * |
Women (n (%)) | 76 (50.7) | 25 (53.2) | 0.867 ° |
Men (n (%)) | 74 (49.3) | 22(46.8) | |
Length of hospital stay (days) | 10.6 ± 6.5 | 14.2 ± 9.2 | <0.01 ^ |
Hypertension (n (%)) | 106 (70.6) | 34 (72.3) | 1.000 ° |
Myocardial infarction (n (%)) | 24 (16) | 5 (10.6) | 0.481 ° |
Congestive heart failure (n (%)) | 19 (12.7) | 5 (10.6) | 0.804 ° |
Peripheral vascular disease (n (%)) | 25 (16.7) | 7 (14.9) | 1.000 ° |
Cerebrovascular disease (n (%)) | 22 (14.7) | 13 (27.6) | 0.05 ° |
Dementia (n (%)) | 3 (2) | 2 (4.2) | 0.335 ° |
Chronic obstruction pulmonary disease (n (%)) | 17 (11.3) | 4 (8.5) | 0.788 ° |
Connective tissue disease (n (%)) | 9 (6) | 3 (6.3) | 1.000 ° |
Peptic ulcer disease (n (%)) | 5 (3.3) | 1 (2.1) | 1.000 ° |
Diabetes mellitus (n (%)) | 16 (10.7) | 6 (12.8) | 0.582 ° |
Chronic kidney disease (n (%)) | 0 (0) | 2 (4.3) | 0.056 ° |
Hemiplegia (n (%)) | 1 (0.6) | 3 (6.3) | 0.041 ° |
Leukemia and/or malignant lymphoma (n (%)) | 4 (2.7) | 3 (6.4) | 0.361 ° |
Solid tumor without metastasis (n (%)) | 10 (6.7) | 5 (10.6) | 0.358 ° |
Solid tumor with metastasis (n (%)) | 3 (2) | 8 (17) | 0.001 ° |
Liver disease (n (%)) | 8 (5.3) | 2 (4.2) | 1.000 ° |
AIDS (n (%)) | 0 (0) | 0 (0) | - |
Charlson comorbidity index | 4.5 ± 1.9 | 6.3 ± 2.4 | <0.001 ^ |
Charlson comorbidity index ≥ 4 (n (%)) | 100 (66.7) | 43 (91.5) | 0.001 ° |
Hazard Ratio | Lower 95% Confidence Interval | Higher 95% Confidence Interval | p | |
---|---|---|---|---|
Age | 1.039 | 0.990 | 1.091 | 0.120 |
Sex | 0.960 | 0.540 | 1.708 | 0.890 |
CCI | 1.132 | 1.009 | 1.270 | 0.035 |
Open surgery | 10.298 | 1.409 | 75.285 | 0.022 |
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Fabbian, F.; De Giorgi, A.; Ferro, S.; Lacavalla, D.; Andreotti, D.; Ascanelli, S.; Volpato, S.; Occhionorelli, S. Post-Operative All-Cause Mortality in Elderly Patients Undergoing Abdominal Emergency Surgery: Role of Charlson Comorbidity Index. Healthcare 2021, 9, 805. https://doi.org/10.3390/healthcare9070805
Fabbian F, De Giorgi A, Ferro S, Lacavalla D, Andreotti D, Ascanelli S, Volpato S, Occhionorelli S. Post-Operative All-Cause Mortality in Elderly Patients Undergoing Abdominal Emergency Surgery: Role of Charlson Comorbidity Index. Healthcare. 2021; 9(7):805. https://doi.org/10.3390/healthcare9070805
Chicago/Turabian StyleFabbian, Fabio, Alfredo De Giorgi, Silvia Ferro, Domenico Lacavalla, Dario Andreotti, Simona Ascanelli, Stefano Volpato, and Savino Occhionorelli. 2021. "Post-Operative All-Cause Mortality in Elderly Patients Undergoing Abdominal Emergency Surgery: Role of Charlson Comorbidity Index" Healthcare 9, no. 7: 805. https://doi.org/10.3390/healthcare9070805