Preparation and Application of a Fast, Naked-Eye, Highly Selective, and Highly Sensitive Fluorescent Probe of Schiff Base for Detection of Cu2+
Abstract
:1. Introduction
2. Experiments
2.1. Reagents and Chemicals
2.2. Synthesis of MPMC
2.2.1. Synthesis of Edaravone
2.2.2. Synthesis of Edaravone Aldehyde Derivative
2.2.3. Synthesis of Ethyl Coumarin-3-Carboxylate
2.2.4. Synthesis of Coumarin-3-Carbohydrazide
2.2.5. Synthesis of MPMC Probe
2.3. General Procedure for the Spectrum Measurement
3. Results and Discussion
3.1. Fluorescence Spectra of the MPMC Probe for Selectivity and Anti-Interference Detection
3.2. Titration Experiment of the MPMC Probe to Cu2+
3.3. Study of EDTA Effect of MPMC Probe on Cu2+
3.4. Study of pH Effect of MPMC Probe to Cu2+
3.5. Study of the Response Time of MPMC Probe to Cu2+
3.6. Contact Mode Detection between MPMC Probe and Cu2+
3.7. The Test Paper for Cu2+ Ions
4. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Compound | Molecular Formula | Solvent | Repeatability | Detection Limit | Reference |
---|---|---|---|---|---|
C18H19N5O3 | CH3CN:HEPES (3:2, v/v) | No | 0.12 μM | [20] | |
C37H27NO3 | THF/H2O | No | 0.36 μM | [22] | |
C22H14N4O | EtOH-HEPES | No | 157 nM | [32] | |
C23H16N4O3 | Tris-HCl buffer solution | Yes | 84 nM | [33] | |
C23H16N2O5 | EtOH-HEPES (80:20, v/v) | No | 6.14 × 10−7 M | [34] | |
C19H13N3O2S | DMSO:H2O (1:9, v/v) | No | 20.0 nM | [35] | |
C16H9F3O4 | CH3CN/HEPES (95/5, v/v) | No | 24.5 nM | [36] | |
C19H15N3OS | DMSO | No | 3.3 μM | [37] | |
C45H36N4O8S4 | 50% CH3CN and 20 mM HEPES | No | 390 nM | [38] | |
C20H22N2O2 | Water/DMF (9.9/0.1) | No | - | [39] | |
C13H11BrN2O2S | DMSO | No | 2.35 μM | [40] | |
C21H16N4O4 | EtOH/H2O (1:1, v/v) | Yes | 10.23 nM | This work |
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Liu, J.; Cheng, P.-Y.; Chen, S.; Wang, M.; Wei, K.; Li, Y.; Cao, Y.-Y.; Wang, X.; Li, H.-L. Preparation and Application of a Fast, Naked-Eye, Highly Selective, and Highly Sensitive Fluorescent Probe of Schiff Base for Detection of Cu2+. Chemosensors 2023, 11, 556. https://doi.org/10.3390/chemosensors11110556
Liu J, Cheng P-Y, Chen S, Wang M, Wei K, Li Y, Cao Y-Y, Wang X, Li H-L. Preparation and Application of a Fast, Naked-Eye, Highly Selective, and Highly Sensitive Fluorescent Probe of Schiff Base for Detection of Cu2+. Chemosensors. 2023; 11(11):556. https://doi.org/10.3390/chemosensors11110556
Chicago/Turabian StyleLiu, Juan, Peng-Yu Cheng, Sai Chen, Meng Wang, Kai Wei, Yuan Li, Yao-Yao Cao, Xing Wang, and Hong-Lei Li. 2023. "Preparation and Application of a Fast, Naked-Eye, Highly Selective, and Highly Sensitive Fluorescent Probe of Schiff Base for Detection of Cu2+" Chemosensors 11, no. 11: 556. https://doi.org/10.3390/chemosensors11110556