Next Article in Journal
Whole Exome Sequencing Identifies PHF14 Mutations in Neurocytoma and Predicts Responsivity to the PDGFR Inhibitor Sunitinib
Next Article in Special Issue
Role of Hyaluronic Acid in Selected Malignant Neoplasms in Women
Previous Article in Journal
Artificial Intelligence for Early Detection of Chest Nodules in X-ray Images
Previous Article in Special Issue
Chemopreventive Effects of Oral Pterostilbene in Multistage Carcinogenesis of Skin Squamous Cell Carcinoma Mouse Model Induced by DMBA/TPA
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Biomedicines
Volume 10
Issue 11
10.3390/biomedicines10112841
Review Report
biomedicines-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
Review
Peer-Review Record

Polysaccharide-Peptide from Trametes versicolor: The Potential Medicine for Colorectal Cancer Treatment

Biomedicines 2022, 10(11), 2841; https://doi.org/10.3390/biomedicines10112841
by Zhicheng He 1,2, Jian Lin 1,2, Yingying He 3,* and Shubai Liu 1,2,*
Reviewer 1: Anonymous
Biomedicines 2022, 10(11), 2841; https://doi.org/10.3390/biomedicines10112841
Submission received: 15 September 2022 / Revised: 25 October 2022 / Accepted: 31 October 2022 / Published: 7 November 2022
(This article belongs to the Special Issue Anticancer Activity and Metabolic Pathways of Natural Products)

Round 1

Reviewer 1 Report

Reviewer: Recommendation: The Article review titled as “Polysaccharide-peptide from Trametes versicolor: the potential medicine for colorectal cancer treatment.” may be publishable, but it should be reviewed after minor revisions Comments: The review provides in depth information, the article is well written; the references are appropriate. Therefore, its publication in “Biomedicines” is recommended after minor revision. Additional comments: Page No, 2, Line 65, Keep the KDa format consistent throughout the article. Page No. 2, Line 66, “He et al15 .” remove the space Page No. 4, Line 192, “IC50” 50 need to be subscript in entire article. Page No. 5, Figure 1, Cleanup he figures 1A and B. Text are tiny and not readable clearly. Resolution is poor. Page No. 9, Figure 2, Cite the references from where the structure was taken from. In reference section please keep the journal writing style (as per Biomedicines) CONSISTENT for all the listed references. Text size throughout the review is not consistent, please correct accordingly

Author Response

Dear reviewer,

        Our point-by-point response to the comments submit as PDF document. Please see the attachment.

Author Response File: Author Response.pdf

Reviewer 2 Report

1- Abstract lacks the conclusion or recommendation of the review.

2- line 46. uses not italic.

3- line 82. including not italic.

4- line 100. extract(s) not extraction.

5- talking about PSK & PSP should be accompanied with some details about the structure/composition. illustrative figure will be preferably added.

6- narration of antitumor activity lacks mentioning the nature of solvents used in extraction, if they polar or non.

7- I see that this work should include some in vivo studies concerning the cytotoxicity, cytotoxicity on the in vitro scale is not sufficient. also, some immunological studies should be merged to elaborate clearly the action mechanism.

Author Response

Dear reviewer,

Our point-by-point response to the comments submit as PDF document. Please see the attachment.

Author Response File: Author Response.pdf

Round 2

Reviewer 2 Report

The review article still needs more careful revision to valorize/maximize the benefit to the readers.

Back to TopTop