Healing of Recurrent Aphthous Stomatitis by Non-Thermal Plasma: Pilot Study
Abstract
:1. Introduction
2. Materials and Methods
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Recurrent Herpetiform Ulcers | Major Recurrent Ulcers | Minor Recurrent Ulcers | Fisher’s Exact | |
---|---|---|---|---|
Gender | ||||
Male | 10 | 0.01 | ||
Female | 1 | 10 | 9 | |
Age | ||||
18–30 | 2 | 9 | 0.005 | |
31–50 | 1 | 7 | ||
51–67 | 8 | 3 | ||
Marital status | ||||
Married | 1 | 8 | 6 | 0.02 |
Single | 2 | 13 | ||
Scholarship | ||||
High school | 2 | 3 | 0.04 | |
Basic | 1 | 8 | 6 | |
Bachelor’s degree | 10 | |||
Occupation | ||||
Unemployed | 3 | 1 | 0.003 | |
Student | 2 | 3 | ||
Homework | 1 | 5 | 1 | |
Employee | 14 | |||
Medication consumption | ||||
Not | 1 | 2 | 11 | 0.08 |
Yes | 8 | 8 | ||
Smoking | ||||
Cigarette | 3 | 4 | 0.73 | |
No | 1 | 7 | 15 | |
Alcohol consumption | ||||
2 to 4 times a month | 1 | 0.02 | ||
Never | 1 | 8 | 4 | |
Once a year | 1 | 8 | ||
Once a month | 7 | |||
Ulcers evolution time | ||||
Two to five days | 1 | 4 | 10 | 0.69 |
Six to ten days | 6 | 8 | ||
One day | 1 | |||
Ulcers recurrence period | ||||
Zero | 1 | 0.07 | ||
One for year | 1 | 5 | 2 | |
One for month | 5 | 5 | ||
One for week | 3 | |||
More than a year | 8 |
Mean and Standard Deviation of Ulcer Size | ||
---|---|---|
Initial | 6.9 ± 4.51 A | |
One hour | 3.96 ± 3.1 B | |
One day | 2 ± 2 BC | |
One week | 0.03 ± 0.18 C | |
p | <0.0001 | |
Mean and Standard Deviation of Pain | ||
Initial | 7.1 ± 2.5 A | |
One hour | 1.5 ± 2.3 B | |
One day | 0.2 ± 0.7 C | |
One week | 0.06 ± 0.3 C | |
p | <0.0001 | |
Mean and Standard Deviation of Erythema Size | ||
Initial | 2.1 ± 1.1 A | |
One hour | 1.4 ± 1 B | |
One day | 0.5 ± 0.6 C | |
One week | 0.03 ± 0.18 C | |
p | <0.0001 |
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Ibáñez-Mancera, N.G.; López-Callejas, R.; Toral-Rizo, V.H.; Rodríguez-Méndez, B.G.; Lara-Carrillo, E.; Peña-Eguiluz, R.; do Amaral, R.C.; Mercado-Cabrera, A.; Valencia-Alvarado, R. Healing of Recurrent Aphthous Stomatitis by Non-Thermal Plasma: Pilot Study. Biomedicines 2023, 11, 167. https://doi.org/10.3390/biomedicines11010167
Ibáñez-Mancera NG, López-Callejas R, Toral-Rizo VH, Rodríguez-Méndez BG, Lara-Carrillo E, Peña-Eguiluz R, do Amaral RC, Mercado-Cabrera A, Valencia-Alvarado R. Healing of Recurrent Aphthous Stomatitis by Non-Thermal Plasma: Pilot Study. Biomedicines. 2023; 11(1):167. https://doi.org/10.3390/biomedicines11010167
Chicago/Turabian StyleIbáñez-Mancera, Norma Guadalupe, Régulo López-Callejas, Víctor Hugo Toral-Rizo, Benjamín Gonzalo Rodríguez-Méndez, Edith Lara-Carrillo, Rosendo Peña-Eguiluz, Regiane Cristina do Amaral, Antonio Mercado-Cabrera, and Raúl Valencia-Alvarado. 2023. "Healing of Recurrent Aphthous Stomatitis by Non-Thermal Plasma: Pilot Study" Biomedicines 11, no. 1: 167. https://doi.org/10.3390/biomedicines11010167