Changes in AmotL2 Expression in Cells of the Human Enteral Nervous System in Oxaliplatin-Induced Enteric Neuropathy
Abstract
:1. Introduction
2. Materials and Methods
2.1. Patients and Samples
2.2. Immunohistochemistry
2.3. Image Quantitative Analysis and Statistics
3. Results
3.1. ENS Neurons and Glial Identification
3.2. Quantification of Neurons and Glial Cells of the ENS
3.3. TNF-α Expression in the ENS
3.4. OxPt Treatment Effects over AmotL2 Expression
3.5. Variations in AmotL2 Expression in the Enteric Nervous System in Samples from Patients Treated with OxPt-Based Chemotherapy
4. Discussion
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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González-Fernández, R.; Martín-Ramírez, R.; Maeso, M.-d.-C.; Lázaro, A.; Ávila, J.; Martín-Vasallo, P.; Morales, M. Changes in AmotL2 Expression in Cells of the Human Enteral Nervous System in Oxaliplatin-Induced Enteric Neuropathy. Biomedicines 2024, 12, 1952. https://doi.org/10.3390/biomedicines12091952
González-Fernández R, Martín-Ramírez R, Maeso M-d-C, Lázaro A, Ávila J, Martín-Vasallo P, Morales M. Changes in AmotL2 Expression in Cells of the Human Enteral Nervous System in Oxaliplatin-Induced Enteric Neuropathy. Biomedicines. 2024; 12(9):1952. https://doi.org/10.3390/biomedicines12091952
Chicago/Turabian StyleGonzález-Fernández, Rebeca, Rita Martín-Ramírez, María-del-Carmen Maeso, Alberto Lázaro, Julio Ávila, Pablo Martín-Vasallo, and Manuel Morales. 2024. "Changes in AmotL2 Expression in Cells of the Human Enteral Nervous System in Oxaliplatin-Induced Enteric Neuropathy" Biomedicines 12, no. 9: 1952. https://doi.org/10.3390/biomedicines12091952