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Review

Photodynamic Therapy in Ocular Oncology

by
Maria Antonietta Blasi
*,
Monica Maria Pagliara
,
Angela Lanza
,
Maria Grazia Sammarco
,
Carmela Grazia Caputo
,
Gabriela Grimaldi
and
Andrea Scupola
Department of Ophthalmology, Catholic University, 00168 Rome, Italy
*
Author to whom correspondence should be addressed.
Biomedicines 2018, 6(1), 17; https://doi.org/10.3390/biomedicines6010017
Submission received: 30 October 2017 / Revised: 8 January 2018 / Accepted: 30 January 2018 / Published: 7 February 2018
(This article belongs to the Special Issue Photodynamic Therapy in Cancer)

Abstract

Although introduced for the treatment of maculopathies, photodynamic therapy (PDT) is now largely used in some eye cancers treatment. The selective tissue damage with PDT is achieved by sequestration of the photosensitizer in the target tissue and focal activation of the photosensitizer by low energy directed light. In this way, it is possible to achieve the destruction of the tumor tissue by safeguarding the surrounding healthy structures. Our study describes the clinical uses and efficacy of photodynamic therapy in ocular oncology.
Keywords: photodynamic therapy (PDT); PDT; ocular tumors; uveal melanoma; choroidal hemangioma; uveal metastases; vasoproliferative tumors photodynamic therapy (PDT); PDT; ocular tumors; uveal melanoma; choroidal hemangioma; uveal metastases; vasoproliferative tumors

Share and Cite

MDPI and ACS Style

Blasi, M.A.; Pagliara, M.M.; Lanza, A.; Sammarco, M.G.; Caputo, C.G.; Grimaldi, G.; Scupola, A. Photodynamic Therapy in Ocular Oncology. Biomedicines 2018, 6, 17. https://doi.org/10.3390/biomedicines6010017

AMA Style

Blasi MA, Pagliara MM, Lanza A, Sammarco MG, Caputo CG, Grimaldi G, Scupola A. Photodynamic Therapy in Ocular Oncology. Biomedicines. 2018; 6(1):17. https://doi.org/10.3390/biomedicines6010017

Chicago/Turabian Style

Blasi, Maria Antonietta, Monica Maria Pagliara, Angela Lanza, Maria Grazia Sammarco, Carmela Grazia Caputo, Gabriela Grimaldi, and Andrea Scupola. 2018. "Photodynamic Therapy in Ocular Oncology" Biomedicines 6, no. 1: 17. https://doi.org/10.3390/biomedicines6010017

APA Style

Blasi, M. A., Pagliara, M. M., Lanza, A., Sammarco, M. G., Caputo, C. G., Grimaldi, G., & Scupola, A. (2018). Photodynamic Therapy in Ocular Oncology. Biomedicines, 6(1), 17. https://doi.org/10.3390/biomedicines6010017

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