Phospholipase A2 (PLA2) as an Early Indicator of Envenomation in Australian Elapid Snakebites (ASP-27)
Abstract
:1. Introduction
2. Experimental Section
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Snake | No. | Phospholipase A2 (nmol/min/mL); Median, IQR and Range | Venom Concentration (ng/L); Median, IQR and Range |
---|---|---|---|
Non-envenomated | 80 | 9 (7 to 11; 1 to 16) | NA |
Brown snake (Pseudonaja textilis) | 33 | 10 (6.5 to 13; 1 to 107) | 2.6 (0.9 to 8; 0.2 to 95) |
Tiger snake (Notechis scutatus) | 24 | 34 (12 to 68; 1 to 68) | 7 (2.2 to 25; 0.2 to 93) |
Red-bellied black snake (Pseudechis porphyriacus) | 19 | 82 (30 to 212; 3 to 637) | 11 (3 to 51; 0.2 to 122) |
Rough-scale snake (Tropidechis carinatus) | 17 | 29 (14 to 69; 5 to 201) | 14 (5.8 to 27; 0.5 to 83) |
Taipan (Oxyuranus scutellatus) | 7 | 30 (16 to 106; 10 to 252) | 32 (17 to 227; 9 to 303) |
Death Adder (Acanthophis antarcticus) | 7 | 31 (13 to 63; 5 to 73) | 7 (3.2 to 23; 1.3 to 36) |
Mulga snake (Pseudechis australis) | 3 | 7, 67, 409 | 7, 17, 24 |
Collett’s Snake (Pseudechis colletti) | 1 | 597 | 173 |
Stephen’s banded snake (Hoplocephalus stephensii) | 2 | 9, 55 | 25 |
Broad-headed snake (Hoplocepalus bungaroides) | 2 | 11, 11 | 3.6 |
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Isbister, G.K.; Mirajkar, N.; Fakes, K.; Brown, S.G.A.; Veerati, P.C. Phospholipase A2 (PLA2) as an Early Indicator of Envenomation in Australian Elapid Snakebites (ASP-27). Biomedicines 2020, 8, 459. https://doi.org/10.3390/biomedicines8110459
Isbister GK, Mirajkar N, Fakes K, Brown SGA, Veerati PC. Phospholipase A2 (PLA2) as an Early Indicator of Envenomation in Australian Elapid Snakebites (ASP-27). Biomedicines. 2020; 8(11):459. https://doi.org/10.3390/biomedicines8110459
Chicago/Turabian StyleIsbister, Geoffrey K., Nandita Mirajkar, Kellie Fakes, Simon G. A. Brown, and Punnam Chander Veerati. 2020. "Phospholipase A2 (PLA2) as an Early Indicator of Envenomation in Australian Elapid Snakebites (ASP-27)" Biomedicines 8, no. 11: 459. https://doi.org/10.3390/biomedicines8110459