Does the ST2 Level in Pediatric Heart Failure Patients Correlate with Cardiovascular Events and Mortality?
Abstract
:1. Introduction
2. Materials and Methods
3. Results
4. Discussion
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Median (Min–Max) | ||
---|---|---|
Age (month) | 55.5 (1–228) | |
Height (cm) | 114 (50–176) | |
Weight (kg) | 16.00 (2.6–90) | |
Gender | F | 53.4% |
M | 46.6% | |
Oxygen saturation (%) | 98 (74–100) | |
PAP (mmHg) | 20 (10–99) | |
Qp/Qs | 1.85 (1–2.6) | |
Pro BNP (pg/mL) | 313 (17–22,243) | |
sST2 (pg/mL) | 1110 (530–8440) | |
MACE | 76.3% | |
Lower respiratory tract infection | 17.2% | |
Arrhythmia | 3.4% | |
Interventional Angiography | 50% | |
Cardiovascular surgery | 25.9% | |
Growth retardation | 31% | |
Hospitalization | 15.5% | |
Organ dysfunction | 5.2% | |
Mortality | 1.7% |
MACE (−) | MACE (+) | p | |
---|---|---|---|
Age (month) | 69.0 (1.5–204) | 53.0 (1–228) | 0.592 |
Height (cm) | 139 (52–160) | 113 (50–176) | 0.312 |
Weight (kg) | 15.25 (2.9–87) | 16.40 (2.6–90) | 0.702 |
Oxygen saturation (%) | 98 (94–100) | 97 (74–100) | 0.214 |
PAP (mmHg) | 47 (23–70) | 20 (10–99) | 0.142 |
Qp/Qs | 1.00 | 1.90 (1.1–2.6) | 0.095 |
Ross score | 3 (1–6) | 4 (0–10) | 0.233 |
NYHA stage | 2 (2) | 2 (2–3) | 0.303 |
Pro BNP | 258 (20–9204) | 314 (17–22,243) | 0.808 |
sST2 (pg/mL) | 955 (665–3290) | 1245 (530–8440) | 0.277 |
Pro BNP (pg/mL) Median (Min–Max) | p | ST2 (pg/mL) Median (Min–Max) | p | ||
---|---|---|---|---|---|
MACE | − | 2588 (20–9204) | 0.808 | 955 (665–3290) | 0.277 |
+ | 314 (17–22,243) | 1245 (530–8440) | |||
Lower respiratory tract infection | − | 198 (17–9204) | 0.001 | 1040 (530–3290) | 0.064 |
+ | 5841 (313–22,243) | 1313 (800–8440) | |||
Arrhythmia | − | 286 (17–22,243) | 0.483 | 1110 (530–8440) | 0.701 |
+ | 3432 (217–6646) | 2965 (800–5130) | |||
Interventional angiography | − | 742 (20–22,243) | 0.019 | 905 (560–8440) | 0.286 |
+ | 193 (17–1354) | 1245 (530–2675) | |||
Cardiovascular surgery | − | 245 (17–9204) | 0.096 | 1040 (530–5165) | 0.702 |
+ | 2853 (148–22,243) | 1280 (560−8440) | |||
Growth retardation | − | 196 (20–9204) | 0.011 | 1023 (530−2675) | 0.037 |
+ | 807 (17–22,243) | 1313 (700–8440) | |||
Hospitalization | − | 198 (17–9204) | 0.001 | 1040 (530–3290) | 0.107 |
+ | 5841 (313–22,243) | 1280 (800–8440) | |||
Organ dysfunction | − | 258 (17–9204) | 0.007 | 1110 (530−8440) | 0.765 |
+ | 14,023 (6646–22,243) | 800 (800–2335) | |||
Mortality | − | 313 (17–14,023) | 0.093 | 1075 (530–8440) | 0.143 |
+ | 22,243 (22,243–22,243) | 2335 |
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Sulu, A.; Uner, G.; Kosger, P.; Ucar, B. Does the ST2 Level in Pediatric Heart Failure Patients Correlate with Cardiovascular Events and Mortality? Children 2024, 11, 718. https://doi.org/10.3390/children11060718
Sulu A, Uner G, Kosger P, Ucar B. Does the ST2 Level in Pediatric Heart Failure Patients Correlate with Cardiovascular Events and Mortality? Children. 2024; 11(6):718. https://doi.org/10.3390/children11060718
Chicago/Turabian StyleSulu, Ayse, Gulcan Uner, Pelin Kosger, and Birsen Ucar. 2024. "Does the ST2 Level in Pediatric Heart Failure Patients Correlate with Cardiovascular Events and Mortality?" Children 11, no. 6: 718. https://doi.org/10.3390/children11060718