Mandibular Kinematics on an Orthodontic Population Assessed with an Optical Jaw Tracking System: A Comparative Study
Abstract
:1. Introduction
2. Materials and Methods
2.1. Patient Selection
2.2. Inclusion Criteria
- Permanent dentition;
- Complete set of orthodontic records.
2.3. Exclusion Criteria
- Previous orthodontic or splint treatment;
- Overjet > 8 mm;
- A 100% incisor overlap;
- History of trauma or surgery in the maxillofacial area;
- Systemic conditions affecting the orofacial region;
- Unreliable Modjaw® readings.
2.4. TMD Diagnosis
2.5. Data Collection and Analysis
- Presence or absence of TMD signs/symptoms;
- Age;
- Gender;
- Centric occlusion–maximum intercuspation (CO-MI) discrepancy (Modjaw vertical and sagittal, right and left, and transverse) (in mm);
- Overjet (in mm);
- Overbite (in mm);
- Maximum opening (in mm);
- Sagittal condylar guidance (right and left) (in degrees);
- Bennett angles (right and left) (in degrees);
- Angle classification;
- Skeletal classification (ANB angle).
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
Abbreviations
TMJ | Temporomandibular joint |
TMD | Temporomandibular dysfunction |
CR | Centric relation |
CO | Centric occlusion |
MI | Maximum intercuspation |
MJ | Modjaw |
SAG | Sagittal |
VERT | Vertical |
TRANS | Transverse |
L | Left |
R | Right |
References
- Okeson, J. Management of Temporomandibular Disorders and Occlusion, 7th ed.; Elsevier: Amsterdam, The Netherlands; Mosby: St. Louis, MO, USA, 2008. [Google Scholar]
- Singh, S.; Rehan, S.; Palaskar, J.N.; Mittal, S.K. Hinge axis—Location, clinical use and controversies. J. Res. Dent. 2017, 4, 158–161. [Google Scholar] [CrossRef]
- García, M.; Cabrera, J.; Bataller, A.; Postigo, S.; Castillo, J. 3D Kinematic mandible model to design mandibular advancement devices for the treatment of obstructive sleep apnea. Bio-Des. Manuf. 2021, 4, 22–32. [Google Scholar] [CrossRef]
- Laird, M.; Ross, C.; O’Higgins, P. Jaw kinematics and mandibular morphology in humans. J. Hum. Evol. 2020, 139, 102639. [Google Scholar] [CrossRef] [PubMed]
- Zieliński, G.; Pająk-Zielińska, B.; Pająk, A.; Wójcicki, M.; Litko-Rola, M.; Ginszt, M. Global co-occurrence of bruxism and temporomandibular disorders: A meta-regression analysis. Dent. Med. Probl. 2025. Online ahead of print. [Google Scholar]
- Scolaro, A.; Khijmatgar, S.; Rai, P.; Falsarone, F.; Alicchio, F.; Mosca, A.; Greco, C.; Del Fabbro, M.; Tartaglia, G. Efficacy of Kinematic Parameters for Assessment of Temporomandibular Joint Function and Disfunction: A Systematic Review and Meta-Analysis. Bioengineering 2022, 9, 269. [Google Scholar] [CrossRef] [PubMed]
- Woodford, S.; Robinson, D.; Mehl, A.; Lee, P.; Ackland, D. Measurement of normal and pathological mandibular and temporomandibular joint kinematics: A systematic review. J. Biomech. 2020, 111, 109994. [Google Scholar] [CrossRef]
- Revilla-León, M.; Fernández-Estevan, L.; Barmak, A.B.; Kois, J.C.; Pérez-Barquero, J.A. Accuracy of the maxillomandibular relationship at centric relation position recorded by using 3 different intraoral scanners with or without an optical jaw tracking system: An in vivo pilot study. J. Dent. 2023, 132, 104478. [Google Scholar] [CrossRef]
- Bernauer, S.; Zitzmann, N.; Joda, T. The Use and Performance of Artificial Intelligence in Prosthodontics: A Systematic Review. Sensors 2021, 21, 6628. [Google Scholar] [CrossRef]
- Bapelle, M.; Dubromez, J.; Savoldelli, C.; Tillier, Y.; Ehrmann, E. Modjaw(R) device: Analysis of mandibular kinematics recorded for a group of asymptomatic subjects. Cranio 2024, 42, 483–489. [Google Scholar] [CrossRef]
- Cheong, C.; Radomski, K.; Otten, J.; Lee, S. A clinical comparative analysis using an optical tracking device versus conventional tracking device in the production of occlusal appliances. J. Prosthodont. 2024, 34, 350–356. [Google Scholar] [CrossRef]
- Lepidi, L.; Kim, B.C.; Giberti, L.; Suriano, C.; Li, J.; Grande, F. The 4D virtual patient: A proof of concept in digital dentistry. J. Prosthet. Dent. 2024, in press. [Google Scholar] [CrossRef]
- Revilla-Leon, M.; Agustin-Panadero, R.; Zeitler, J.M.; Barmak, A.B.; Yilmaz, B.; Kois, J.C.; Perez-Barquero, J.A. Differences in maxillomandibular relationship recorded at centric relation when using a conventional method, four intraoral scanners, and a jaw tracking system: A clinical study. J. Prosthet. Dent. 2023, 132, 964–972. [Google Scholar] [CrossRef] [PubMed]
- Bedrossian, E.A.; Bedrossian, E.; Kois, J.C.; Revilla-Leon, M. Use of an optical jaw-tracking system to record mandibular motion for treatment planning and designing interim and definitive prostheses: A dental technique. J. Prosthet. Dent. 2022, 132, 659–674. [Google Scholar] [CrossRef] [PubMed]
- Lepidi, L.; Suriano, C.; Wang, H.L.; Granata, S.; Joda, T.; Li, J. Digital fixed complete-arch rehabilitation: From virtual articulator mounting to clinical delivery. J. Prosthet. Dent. 2022, 127, 398–403. [Google Scholar] [CrossRef] [PubMed]
- Silveira, S.; Valerio, P.; Machado Júnior, A. The Law of Minimum Vertical Dimension: Evidence for Improvement of Dental Occlusion. Eur. J. Dent. 2022, 16, 241–250. [Google Scholar] [CrossRef]
- De Felício, C.; Mapelli, A.; Sidequersky, F.; Tartaglia, G.; Sforza, C. Mandibular kinematics and masticatory muscles EMG in patients with short lasting TMD of mild-moderate severity. J. Electromyogr. Kinesiol. 2013, 23, 627–633. [Google Scholar] [CrossRef]
- Londoño, A.; Assis, M.; Fornai, C.; Greven, M. Premolar Extraction Affects Mandibular Kinematics. Eur. J. Dent. 2023, 17, 756–764. [Google Scholar] [CrossRef]
- Cuevas, M.; Cacho, A.; Alarcón, J.; Martín, C. Longitudinal evaluation of jaw muscle activity and mandibular kinematics in young patients with Class II malocclusion treated with the Teuscher activator. Med. Oral Patol. Oral Cir. Bucal 2013, 18, e497–e504. [Google Scholar] [CrossRef]
- Clark, J.; Evans, R. Functional occlusal relationships in a group of post-orthodontic patients: Preliminary findings. Eur. J. Orthod. 1998, 20, 103–110. [Google Scholar] [CrossRef]
- von Elm, E.; Altman, D.; Egger, M.; Pocock, S.; Gøtzsche, P.; Vandenbroucke, J. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: Guidelines for reporting observational studies. J. Clin. Epidemiol. 2008, 61, 344–349. [Google Scholar] [CrossRef]
- Hidaka, O.; Adachi, S.; Takada, K. The difference in condylar position between centric relation and centric occlusion in pretreatment Japanese orthodontic patients. Angle Orthod. 2002, 72, 295–301. [Google Scholar]
- Schiffman, E.; Ohrbach, R.; Truelove, E.; Look, J.; Anderson, G.; Goulet, J.P.; List, T.; Svensson, P.; Gonzalez, Y.; Lobbezoo, F.; et al. Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) for Clinical and Research Applications: Recommendations of the International RDC/TMD Consortium Network and Orofacial Pain Special Interest Group. J. Oral Facial Pain Headache 2014, 28, 6–27. [Google Scholar] [CrossRef] [PubMed]
- Schober, P.; Boer, C.; Schwarte, L. Correlation Coefficients: Appropriate Use and Interpretation. Anesth. Analg. 2018, 126, 1763–1768. [Google Scholar] [CrossRef]
- Tashkandi, N.; Asiri, S.; Al Bin Ali, R.; Maalawi, A.; Alwan, S.; Alabood, S.; Alsharif, R. A cross-sectional study into the reasons behind orthodontic re-treatment. J. Orthod. Sci. 2023, 12, 56. [Google Scholar] [CrossRef] [PubMed]
- Marques, L.; Pordeus, I.; Ramos-Jorge, M.; Filogônio, C.; Filogônio, C.; Pereira, L.; Paiva, S. Factors associated with the desire for orthodontic treatment among Brazilian adolescents and their parents. BMC Oral Health 2009, 9, 34. [Google Scholar] [CrossRef] [PubMed]
- Baccetti, T.; Franchi, L.; Cameron, C.; McNamara, J.J. Treatment timing for rapid maxillary expansion. Angle Orthod. 2001, 71, 343–350. [Google Scholar]
- Batista, K.; Thiruvenkatachari, B.; Harrison, J.; O’Brien, K. Orthodontic treatment for prominent upper front teeth (Class II malocclusion) in children and adolescents. Cochrane Database Syst. Rev. 2018, 3, CD003452. [Google Scholar] [CrossRef]
- Feng, Q.; Jiang, F.; Wang, H.; Shen, G.; Zhao, Z.; Jiang, L.; Jiang, C.; Fan, Q.; Zhu, J.; Pan, P.; et al. Evaluation of modified clear Twin Block aligner in treating adolescents with skeletal class II malocclusion: A two-centre cephalometric study. Orthod. Craniofacial Res. 2024, 27, 665–673. [Google Scholar] [CrossRef]
- Proffit, W.; Phillips, C.; Dann, C.T. Who seeks surgical-orthodontic treatment? Int. J. Adult Orthod. Orthognath. Surg. 1990, 5, 153–160. [Google Scholar]
- Cordray, F.E. Articulated dental cast analysis of asymptomatic and symptomatic populations. Int. J. Oral Sci. 2016, 8, 126–132. [Google Scholar] [CrossRef]
- Weffort, S.Y.; de Fantini, S.M. Condylar displacement between centric relation and maximum intercuspation in symptomatic and asymptomatic individuals. Angle Orthod. 2010, 80, 835–842. [Google Scholar] [CrossRef]
- Parakh, M.; Prasad, D.; Hegde, C. A Comparison of Occlusal Schemes with Condylar Inclination and Anterior Guidance in Dentate Individuals. Int. J. Prosthodont. 2024, 37, 505–511. [Google Scholar] [CrossRef] [PubMed]
- Oancea, L.; Munteanu, I.; Macris, A.; Radulescu, S.; Ciocan, T. A Cone-Beam Computed Tomography Assessment of the Relationship between Incisal and Condylar Guidance. Maedica 2023, 18, 257–265. [Google Scholar] [CrossRef]
n | % | ||
---|---|---|---|
Gender | Male | 42 | 27.3 |
Female | 112 | 72.7 | |
Age (years) | 10–19 | 66 | 42.9 |
Minimum = 11 | 20–29 | 35 | 22.7 |
Maximum = 66 | 30–39 | 19 | 12.3 |
Mean = 26.9 | 40–49 | 24 | 15.6 |
Standard deviation = 14.0 | 50–59 | 7 | 4.5 |
60+ | 3 | 1.9 | |
Angle classification | Class I | 57 | 37.0 |
Class II | 42 | 27.3 | |
Class III | 55 | 35.7 | |
Skeletal classification | Class I | 56 | 36.4 |
Class II | 66 | 42.9 | |
Class III | 32 | 20.8 | |
TMD signs/symptoms | No | 105 | 68.2 |
Yes | 49 | 31.8 |
Minimum | Maximum | Mean | SD | CI 95% | |
---|---|---|---|---|---|
CO-MI vertical right | −3.61 | 4.89 | 0.12 | 0.98 | −0.04, 0.27 |
CO-MI vertical left | −3.56 | 3.53 | 0.00 | 0.91 | −0.15, 0.14 |
CO-MI sagittal right | −1.90 | 2.97 | 0.00 | 0.81 | −0.12, 0.13 |
CO-MI sagittal left | −2.70 | 2.38 | 0.02 | 0.76 | −0.10, 0.14 |
CO-MI transversal | −1.36 | 2.06 | 0.00 | 0.49 | −0.08, 0.08 |
CO-MI vertical right—absolute value | 0.00 | 4.89 | 0.67 | 0.73 | 0.55, 0.78 |
CO-MI vertical left—absolute value | 0.00 | 3.56 | 0.62 | 0.66 | 0.51, 0.72 |
CO-MI sagittal right—absolute value | 0.00 | 2.97 | 0.58 | 0.56 | 0.49, 0.67 |
CO-MI sagittal left—absolute value | 0.00 | 2.70 | 0.54 | 0.53 | 0.45, 0.62 |
CO-MI transversal—absolute value | 0.00 | 2.06 | 0.33 | 0.37 | 0.27, 0.39 |
Sagittal condylar guidance right | 7.00 | 85.00 | 49.16 | 12.11 | 47.23, 51.09 |
Sagittal condylar guidance left | 19.00 | 91.00 | 47.94 | 11.81 | 46.06, 49.82 |
Bennett angle right | −16.00 | 32.00 | 6.89 | 8.18 | 5.59, 8.19 |
Bennett angle left | −11.00 | 31.00 | 4.59 | 7.46 | 3.40, 5.78 |
Maximum opening | 3.00 | 51.00 | 35.70 | 6.21 | 34.71, 36.69 |
Overjet | −7.00 | 10.00 | 2.75 | 2.73 | 2.31, 3.18 |
Overbite | −6.00 | 7.50 | 2.21 | 2.41 | 1.83, 2.60 |
Angle Classification | ||||
---|---|---|---|---|
Class I (n = 57) | Class II (n = 42) | Class III (n = 55) | p | |
CO-MI vertical right | 0.19 (1.13) | −0.02 (1.08) | 0.14 (0.71) | 0.246 |
CO-MI vertical left | 0.04 (0.81) | 0.01 (1.11) | −0.07 (0.85) | 0.774 |
CO-MI sagittal right | 0.18 (0.84) a | 0.09 (0.85) ab | −0.24 (0.68) b | 0.016 * |
CO-MI sagittal left | 0.14 (0.83) a | 0.23 (0.75) a | −0.26 (0.58) b | 0.002 ** |
CO-MI transversal | −0.08 (0.42) | 0.02 (0.54) | 0.08 (0.53) | 0.315 |
CO-MI vertical right—absolute value | 0.74 (0.87) ab | 0.81 (0.71) a | 0.48 (0.53) b | 0.014 * |
CO-MI vertical left—absolute value | 0.58 (0.55) | 0.78 (0.78) | 0.53 (0.66) | 0.114 |
CO-MI sagittal right—absolute value | 0.62 (0.58) | 0.59 (0.61) | 0.52 (0.49) | 0.615 |
CO-MI sagittal left—absolute value | 0.58 (0.61) | 0.58 (0.52) | 0.46 (0.44) | 0.558 |
CO-MI transversal—absolute value | 0.31 (0.29) | 0.34 (0.41) | 0.34 (0.41) | 0.907 |
Sagittal condylar guidance right | 46.75 (11.23) a | 53.71 (9.39) b | 48.18 (13.96) a | 0.010 ** |
Sagittal condylar guidance left | 47.63 (10.96) | 50.33 (10.98) | 46.44 (13.13) | 0.216 |
Bennett angle right | 7.25 (7.37) ab | 9.52 (9.42) a | 4.51 (7.37) b | 0.027 * |
Bennett angle left | 4.82 (6.48) a | 8.00 (8.28) a | 1.75 (6.68) b | <0.001 *** |
Maximum opening | 37.24 (5.13) a | 36.92 (4.83) a | 33.18 (7.37) b | 0.004 * |
Overjet | 3.73 (1.77) a | 4.88 (1.89) a | 0.11 (1.87) b | <0.001 *** |
Overbite | 2.95 (1.72) a | 3.74 (2.26) a | 0.28 (1.83) b | <0.001 *** |
Skeletal Classification | ||||
---|---|---|---|---|
Class I (n = 56) | Class II (n = 66) | Class III (n = 32) | p | |
CO-MI vertical right | −0.12 (0.97) | 0.23 (1.10) | 0.29 (0.64) | 0.099 |
CO-MI vertical left | −0.09 (0.70) | 0.10 (1.03) | −0.07 (0.96) | 0.247 |
CO-MI sagittal right | 0.07 (0.75) | 0.09 (0.89) | −0.29 (0.65) | 0.085 |
CO-MI sagittal left | −0.05 (0.67) | 0.17 (0.88) | −0.17 (0.54) | 0.189 |
CO-MI transversal | 0.01 (0.36) | −0.07 (0.51) | 0.15 (0.63) | 0.065 |
CO-MI vertical right—absolute value | 0.62 (0.74) ab | 0.79 (0.79) a | 0.48 (0.51) b | 0.037 * |
CO-MI vertical left—absolute value | 0.54 (0.45) | 0.71 (0.75) | 0.56 (0.78) | 0.217 |
CO-MI sagittal right—absolute value | 0.58 (0.47) | 0.61 (0.65) | 0.51 (0.49) | 0.506 |
CO-MI sagittal left—absolute value | 0.46 (0.48) | 0.65 (0.62) | 0.43 (0.36) | 0.128 |
CO-MI transversal—absolute value | 0.25 (0.26) | 0.35 (0.38) | 0.42 (0.49) | 0.177 |
Sagittal condylar guidance right | 47.50 (11.47) | 50.26 (11.22) | 49.81 (14.79) | 0.305 |
Sagittal condylar guidance left | 48.63 (9.94) | 47.97 (11.74) | 46.69 (14.89) | 0.679 |
Bennett angle right | 5.48 (7.59) a | 9.62 (8.56) b | 3.72 (6.64) a | 0.002 ** |
Bennett angle left | 4.75 (7.69) ab | 5.92 (7.68) a | 1.56 (5.71) b | 0.012 * |
Maximum opening | 35.18 (7.17) | 36.85 (4.98) | 34.25 (6.47) | 0.163 |
Overjet | 2.66 (2.41) a | 4.28 (1.93) b | −0.26 (2.08) c | <0.001 *** |
Overbite | 2.42 (2.14) a | 2.92 (2.54) a | 0.37 (1.54) b | <0.001 *** |
TMD Signs/Symptoms | |||
---|---|---|---|
No (n = 105) | Yes (n = 49) | p | |
CO-MI vertical right | 0.07 (0.75) | 0.22 (1.36) | 0.299 |
CO-MI vertical left | 0.08 (0.73) | −0.18 (1.19) | 0.191 |
CO-MI sagittal right | 0.03 (0.69) | −0.05 (1.01) | 0.313 |
CO-MI sagittal left | 0.05 (0.64) | −0.04 (0.96) | 0.906 |
CO-MI transversal | −0.07 (0.30) | 0.15 (0.74) | 0.066 |
CO-MI vertical right—absolute value | 0.52 (0.53) | 0.97 (0.97) | 0.001 *** |
CO-MI vertical left—absolute value | 0.51 (0.53) | 0.85 (0.85) | 0.011 * |
CO-MI sagittal right—absolute value | 0.50 (0.48) | 0.75 (0.67) | 0.009 ** |
CO-MI sagittal left—absolute value | 0.46 (0.45) | 0.70 (0.65) | 0.025 * |
CO-MI transversal—absolute value | 0.21 (0.22) | 0.58 (0.49) | <0.001 *** |
Sagittal condylar guidance right | 49.30 (10.77) | 48.88 (14.70) | 0.755 |
Sagittal condylar guidance left | 48.31 (9.89) | 47.14 (15.22) | 0.664 |
Bennett angle right | 6.07 (7.43) | 8.65 (9.42) | 0.234 |
Bennett angle left | 4.40 (7.18) | 5.00 (8.10) | 0.721 |
Maximum opening | 35.76 (6.34) | 35.58 (6.01) | 0.422 |
Overjet | 2.82 (2.65) | 2.59 (2.92) | 0.820 |
Overbite | 2.16 (2.42) | 2.32 (2.41) | 0.709 |
Correlation Coefficient | |
---|---|
Bennett angle left vs. CO-MI sagittal right (absolute value) | RS = 0.176, p = 0.029 * |
Bennett angle right vs. CO-MI sagittal left (absolute value) | RS = 0.216, p = 0.007 ** |
Bennett angle right vs. sagittal condylar guidance right | RS = 0.293, p < 0.001 *** |
Bennett angle right vs. sagittal condylar guidance left | RS = 0.163, p = 0.043 * |
Bennett angle left vs. sagittal condylar guidance right | RS = 0.174, p = 0.031 * |
Bennett angle left vs. sagittal condylar guidance left | RS = 0.190, p = 0.018 * |
Bennett angle right vs. CO-MI transversal | RS = 0.047, p = 0.566 |
Bennett angle right vs. CO-MI transversal (absolute value) | RS = 0.026, p = 0.752 |
Bennett angle left vs. CO-MI transversal | RS = 0.076, p = 0.346 |
Bennett angle left vs. CO-MI transversal (absolute value) | RS = 0.088, p = 0.278 |
Overjet vs. CO-MI sagittal right | RS = 0.206, p = 0.010 ** |
Overjet vs. CO-MI sagittal left | RS = 0.209, p = 0.009 ** |
Sagittal condylar guidance right vs. sagittal condylar guidance left | RS = 0.553, p < 0.001 *** |
Sagittal condylar guidance right vs. overjet | RS = 0.075, p = 0.355 |
Sagittal condylar guidance right vs. overbite | RS = 0.157, p = 0.052 |
Sagittal condylar guidance left vs. overjet | RS = 0.119, p = 0.140 |
Sagittal condylar guidance left vs. overbite | RS = 0.178, p = 0.027 ** |
Age vs. CO-MI vertical right | RS = −0.049, p = 0.547 |
Age vs. CO-MI vertical left | RS = 0.009, p = 0.911 |
Age vs. CO-MI sagittal right | RS = −0.130, p = 0.107 |
Age vs. CO-MI sagittal left | RS = −0.148, p = 0.066 |
Age vs. CO-MI transversal | RS = −0.022, p = 0.785 |
Age vs. sagittal condylar guidance right | RS = 0.037, p = 0.652 |
Age vs. sagittal condylar guidance left | RS = 0.062, p = 0.443 |
Age vs. Bennett angle right | RS = −0.114, p = 0.160 |
Age vs. Bennett angle left | RS = −0.220, p = 0.006 ** |
Age vs. maximum opening | RS = −0.071, p = 0.385 |
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Silva, J.; Azevedo, A.; Martins, E.; Canabez, A.; Martin, D.; Martin, C. Mandibular Kinematics on an Orthodontic Population Assessed with an Optical Jaw Tracking System: A Comparative Study. Dent. J. 2025, 13, 184. https://doi.org/10.3390/dj13050184
Silva J, Azevedo A, Martins E, Canabez A, Martin D, Martin C. Mandibular Kinematics on an Orthodontic Population Assessed with an Optical Jaw Tracking System: A Comparative Study. Dentistry Journal. 2025; 13(5):184. https://doi.org/10.3390/dj13050184
Chicago/Turabian StyleSilva, Joana, Ariana Azevedo, Eugénio Martins, Alberto Canabez, Domingo Martin, and Conchita Martin. 2025. "Mandibular Kinematics on an Orthodontic Population Assessed with an Optical Jaw Tracking System: A Comparative Study" Dentistry Journal 13, no. 5: 184. https://doi.org/10.3390/dj13050184
APA StyleSilva, J., Azevedo, A., Martins, E., Canabez, A., Martin, D., & Martin, C. (2025). Mandibular Kinematics on an Orthodontic Population Assessed with an Optical Jaw Tracking System: A Comparative Study. Dentistry Journal, 13(5), 184. https://doi.org/10.3390/dj13050184