Swept-Source Anterior Segment Optical Coherence Tomography Imaging and Quantification of Bleb Parameters in Glaucoma Filtration Surgery
Abstract
:1. Introduction
2. Methods
2.1. Surgical Technique
2.2. Anterior-Segment Optical Coherence Tomography Imaging of Filtering Bleb
2.3. Image Preprocessing
2.4. Visualisation and Quantification of Surgical Parameters
2.5. Definitions of Surgical Success
2.6. Statistical Analysis
3. Results
3.1. Bleb Height, Scleral Flap and Trabeculo-Descemet Window Dimensions and Surgical Outcomes
3.2. Subanalysis in Deep Sclerectomy Cases Augmented with Intraoperative Mitomycin-C
3.3. Post-Operative Duration and Surgical Outcomes
4. Discussion
4.1. Post-Operative Evaluation of Filtering Blebs
4.2. Swept-Source AS-OCT Technology for More Precise Visualization of Glaucoma Surgeries during the Post-Operative Course
4.3. Use of Anterior Segment-OCT in Post-Operative Bleb Evaluation
4.4. Limitations
5. Conclusions
Author Contributions
Funding
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
Abbreviations
References
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Imaging Plane | Surgical Parameters of Interest | Anatomical Reference Points of Surgical Parameter |
---|---|---|
Sagittal | Scleral flap length | Posterior edge of scleral flap to iridocorneal angle |
Trabeculo-Descemet window length | Anterior edge of TDW to posterior edge of TDW | |
Coronal | Scleral flap width | Nasal edge of scleral flap to temporal edge of scleral flap at midpoint of flap |
Scleral flap thickness | Superior edge of scleral flap to inferior edge of scleral flap at midpoint of flap |
Parameter | CS | QS | F | p Value |
---|---|---|---|---|
Bleb height (mm) | 1.48 | 1.17 | 1.10 | 0.001 |
0.44 | 0.44 | 0.40 | ||
Scleral flap length (mm) | 2.71 | 2.73 | 2.96 | 0.178 |
0.60 | 0.54 | 0.53 | ||
Scleral flap thickness (µm) | 270.40 | 249.90 | 267.60 | 0.437 |
53.54 | 53.15 | 57.26 | ||
Scleral flap width (mm) | 3.85 | 3.56 | 3.71 | 0.088 |
0.44 | 0.47 | 0.58 | ||
Window length (µm) | 519.00 | 432.90 | 441.30 | 0.094 |
206.40 | 164.30 | 146.60 | ||
Scleral flap length, MMC (mm) | 2.77 | 3.11 | 3.15 | 0.150 |
0.54 | 0.45 | 0.51 | ||
Scleral flap thickness, MMC (µm) | 298.30 | 264.40 | 236.60 | 0.027 |
53.48 | 34.79 | 57.81 | ||
Scleral flap width, MMC, (mm) | 3.90 | 3.58 | 3.97 | 0.273 |
0.40 | 0.46 | 0.62 | ||
Window length, MMC (µm) | 613.70 | 378.10 | 450.80 | 0.004 |
200.20 | 127.80 | 152.40 |
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Tan, J.C.K.; Muntasser, H.; Choudhary, A.; Batterbury, M.; Vallabh, N.A. Swept-Source Anterior Segment Optical Coherence Tomography Imaging and Quantification of Bleb Parameters in Glaucoma Filtration Surgery. Bioengineering 2023, 10, 1186. https://doi.org/10.3390/bioengineering10101186
Tan JCK, Muntasser H, Choudhary A, Batterbury M, Vallabh NA. Swept-Source Anterior Segment Optical Coherence Tomography Imaging and Quantification of Bleb Parameters in Glaucoma Filtration Surgery. Bioengineering. 2023; 10(10):1186. https://doi.org/10.3390/bioengineering10101186
Chicago/Turabian StyleTan, Jeremy C.K., Hussameddin Muntasser, Anshoo Choudhary, Mark Batterbury, and Neeru A. Vallabh. 2023. "Swept-Source Anterior Segment Optical Coherence Tomography Imaging and Quantification of Bleb Parameters in Glaucoma Filtration Surgery" Bioengineering 10, no. 10: 1186. https://doi.org/10.3390/bioengineering10101186