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Volume 8
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10.3390/bioengineering8110159
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Review

Where Do We Stand in Stem Cell Therapy for the Management of Diabetes Mellitus?—A Scientometric Research Trend Analysis from 1990 to 2020

by
Sathish Muthu
1,2,3,
Madhan Jeyaraman
2,3,4,*,
Naveen Jeyaraman
3,4,
Ramya Lakshmi Rajendran
5 and
Prakash Gangadaran
5,6,*
1
Department of Orthopaedics, Government Medical College and Hospital, Dindigul 624001, Tamil Nadu, India
2
Department of Biotechnology, School of Engineering and Technology, Sharda University, Greater Noida 201310, Uttar Pradesh, India
3
Indian Stem Cell Study Group (ISCSG) Association, Lucknow 226010, Uttar Pradesh, India
4
Department of Orthopedics, School of Medical Sciences and Research, Sharda University, Greater Noida 201310, Uttar Pradesh, India
5
Department of Nuclear Medicine, School of Medicine, Kyungpook National University, Daegu 41944, Korea
6
BK21 FOUR KNU Convergence Educational Program of Biomedical Sciences for Creative Future Talents, Department of Biomedical Sciences, School of Medicine, Kyungpook National University, Daegu 41944, Korea
*
Authors to whom correspondence should be addressed.
Bioengineering 2021, 8(11), 159; https://doi.org/10.3390/bioengineering8110159
Submission received: 8 October 2021 / Revised: 19 October 2021 / Accepted: 24 October 2021 / Published: 26 October 2021
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Abstract

Stem cell therapy has been considered a promising strategy in the management of both type I and type II diabetes mellitus (DM) because of its immunomodulatory and regenerative capability to restore the beta cell number and function. Various modalities of cellular therapy like transplantation of pancreatic islet cells, transplantation of pancreatic ductal stem cells, and mesenchymal stromal cell transplantation have been tried, and the modality is undergoing rapid advancements that may become the reality in the near future. In the course of its evolution, it is essential to have a comprehensive summary of the progress for a greater capacity to refine our future directives. With technological developments like data mining, graphic drawing, and information analytics combined with computational statistics, visualization of scientific metrology has become a reality. With a newer perspective, we intend to use scientometric tools including text mining, co-word analysis, word frequency analysis, co-citation analysis, cluster network analysis, to perform a systematic and comprehensive analysis of the research trend in stem cell therapy in the management of DM over the past three decades (1990–2020) and to identify the future research hotspots.
Keywords: stem cell; therapy; diabetes mellitus; scientometric research; trend analysis stem cell; therapy; diabetes mellitus; scientometric research; trend analysis

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MDPI and ACS Style

Muthu, S.; Jeyaraman, M.; Jeyaraman, N.; Rajendran, R.L.; Gangadaran, P. Where Do We Stand in Stem Cell Therapy for the Management of Diabetes Mellitus?—A Scientometric Research Trend Analysis from 1990 to 2020. Bioengineering 2021, 8, 159. https://doi.org/10.3390/bioengineering8110159

AMA Style

Muthu S, Jeyaraman M, Jeyaraman N, Rajendran RL, Gangadaran P. Where Do We Stand in Stem Cell Therapy for the Management of Diabetes Mellitus?—A Scientometric Research Trend Analysis from 1990 to 2020. Bioengineering. 2021; 8(11):159. https://doi.org/10.3390/bioengineering8110159

Chicago/Turabian Style

Muthu, Sathish, Madhan Jeyaraman, Naveen Jeyaraman, Ramya Lakshmi Rajendran, and Prakash Gangadaran. 2021. "Where Do We Stand in Stem Cell Therapy for the Management of Diabetes Mellitus?—A Scientometric Research Trend Analysis from 1990 to 2020" Bioengineering 8, no. 11: 159. https://doi.org/10.3390/bioengineering8110159

APA Style

Muthu, S., Jeyaraman, M., Jeyaraman, N., Rajendran, R. L., & Gangadaran, P. (2021). Where Do We Stand in Stem Cell Therapy for the Management of Diabetes Mellitus?—A Scientometric Research Trend Analysis from 1990 to 2020. Bioengineering, 8(11), 159. https://doi.org/10.3390/bioengineering8110159

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