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Journal of Fungi, Volume 4, Issue 2

2018 June - 33 articles

Cover Story: Fungal endophytes have been studied for decades, but few studies have documented the process by which these fungi colonize their plant hosts. In vitro and in vivo experiments were conducted to observe the early stages of endophyte colonization in leaves of Populus trichocarpa (black cottonwood). This scanning electron micrograph shows a germinated conidium of Trichoderma sp., with its hypha entering a stoma 3 days after inoculation. Visualizing the process of leaf colonization contributes to a growing understanding of the ecology and evolution of fungal endophytes, some of the most diverse and common symbionts of plants worldwide. View Paper here.
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Articles (33)

  • Review
  • Open Access
72 Citations
7,431 Views
16 Pages

Recent Advances in the Treatment of Scedosporiosis and Fusariosis

  • Matthew W. McCarthy,
  • Aspasia Katragkou,
  • Elias Iosifidis,
  • Emmanuel Roilides and
  • Thomas J. Walsh

18 June 2018

Species of Scedosporium and Fusarium are considered emerging opportunistic pathogens, causing invasive fungal diseases in humans that are known as scedosporiosis and fusariosis, respectively. These mold infections typically affect patients with immun...

  • Article
  • Open Access
7 Citations
4,530 Views
12 Pages

The Caryopsis of Red-Grained Rice Has Enhanced Resistance to Fungal Attack

  • Alberto Gianinetti,
  • Franca Finocchiaro,
  • Fabio Maisenti,
  • Dailly Kouongni Satsap,
  • Caterina Morcia,
  • Roberta Ghizzoni and
  • Valeria Terzi

14 June 2018

Seed persistence in the soil is threatened by microorganisms, but the seed coat helps protect the seed from them. Although modern rice (Oryza sativa L.) cultivars have a whitish caryopsis, some varieties have a red caryopsis coat, a trait typical of...

  • Article
  • Open Access
1 Citations
4,574 Views
12 Pages

12 June 2018

Certain endophytic fungi belonging to the Hypoxylon genus have recently been found to produce volatile organic compounds (VOCs) that have potential relevance as hydrocarbon fuels. Here, a recently discovered Hypoxylon sp. (BS15) was demonstrated to a...

  • Article
  • Open Access
33 Citations
7,031 Views
9 Pages

Antiplasmodial Properties and Cytotoxicity of Endophytic Fungi from Symphonia globulifera (Clusiaceae)

  • Joël E. T. Ateba,
  • Rufin M. K. Toghueo,
  • Angelbert F. Awantu,
  • Brice M. Mba’ning,
  • Sebastian Gohlke,
  • Dinkar Sahal,
  • Edson Rodrigues-Filho,
  • Etienne Tsamo,
  • Fabrice F. Boyom and
  • Bruno N. Lenta
  • + 1 author

12 June 2018

There is continuing need for new and improved drugs to tackle malaria, which remains a major public health problem, especially in tropical and subtropical regions of the world. Natural products represent credible sources of new antiplasmodial agents...

  • Review
  • Open Access
42 Citations
9,211 Views
11 Pages

8 June 2018

Fungal species undergo many morphological transitions to adapt to changing environments, an important quality especially in fungal pathogens. For decades, Candida albicans has been one of the most prevalent human fungal pathogens, and recently, the p...

  • Review
  • Open Access
27 Citations
5,445 Views
16 Pages

Candida glabrata’s Genome Plasticity Confers a Unique Pattern of Expressed Cell Wall Proteins

  • Eunice López-Fuentes,
  • Guadalupe Gutiérrez-Escobedo,
  • Bea Timmermans,
  • Patrick Van Dijck,
  • Alejandro De Las Peñas and
  • Irene Castaño

5 June 2018

Candida glabrata is the second most common cause of candidemia, and its ability to adhere to different host cell types, to microorganisms, and to medical devices are important virulence factors. Here, we consider three characteristics that confer ext...

  • Article
  • Open Access
37 Citations
6,023 Views
12 Pages

An In Vitro Model for Candida albicans–Streptococcus gordonii Biofilms on Titanium Surfaces

  • Daniel Montelongo-Jauregui,
  • Anand Srinivasan,
  • Anand K. Ramasubramanian and
  • Jose L. Lopez-Ribot

4 June 2018

The oral cavity serves as a nutrient-rich haven for over 600 species of microorganisms. Although many are essential to maintaining the oral microbiota, some can cause oral infections such as caries, periodontitis, mucositis, and endodontic infections...

  • Article
  • Open Access
30 Citations
9,115 Views
16 Pages

Antifungal Activities of Volatile Secondary Metabolites of Four Diaporthe Strains Isolated from Catharanthus roseus

  • Dong-Hui Yan,
  • Xiaoyu Song,
  • Hongchang Li,
  • Tushou Luo,
  • Guiming Dou and
  • Gary Strobel

30 May 2018

Four endophytic fungi were isolated from the medicinal plant, Catharanthus roseus, and were identified as Diaporthe spp. with partial translation elongation factor 1-alpha (TEF1), beta-tubulin (TUB), histone H3 (HIS), calmodulin (CAL) genes, and rDNA...

  • Article
  • Open Access
16 Citations
4,678 Views
12 Pages

Repeated Exposition to Mercury (II) Chloride Enhances Susceptibility to S. schenckii sensu stricto Infection in Mice

  • Alexander Batista-Duharte,
  • Damiana Téllez-Martínez,
  • Juliana Aparecida Jellmayer,
  • Deivys Leandro Portuondo Fuentes,
  • Marisa Campos Polesi,
  • Amanda Martins Baviera and
  • Iracilda Zeppone Carlos

25 May 2018

Sporotrichosis is a subcutaneous mycosis that has re-emerged in several tropical and subtropical regions over the last decades. Growing findings suggest that the interplay of host, pathogen, and environment has a determinant effect on the diversity,...

  • Article
  • Open Access
42 Citations
7,821 Views
17 Pages

24 May 2018

Fusarium spp. and Alternaria spp., two genera of filamentous fungi, are common colonizers of the wheat phyllosphere. Both can be pathogenic and produce mycotoxins that are harmful to consumers. Their in-field infection dynamics have been a focus for...

  • Review
  • Open Access
51 Citations
13,521 Views
10 Pages

Sporotrichosis: From KOH to Molecular Biology

  • Roberto Arenas,
  • Carlos D. Sánchez-Cardenas,
  • Lourdes Ramirez-Hobak,
  • Leon Felipe Ruíz Arriaga and
  • Ma. Elisa Vega Memije

23 May 2018

Sporotrichosis is a cosmopolitan, chronic granulomatous mycosis, acquired by traumatic inoculation and caused by Sporothrix schenckii complex. Several methods of diagnostic are available, from KOH to molecular biology. In this review, we describe fro...

  • Article
  • Open Access
16 Citations
11,155 Views
7 Pages

Estimated Burden of Serious Fungal Infections in Malawi

  • Khumbo Kalua,
  • Boston Zimba and
  • David W. Denning

21 May 2018

Despite efforts to address the burden of fungal infections in Malawi, the prevalence and incidence remain largely unknown. We assessed the annual burden in the general population and among populations at high risk and fungal infection frequencies in...

  • Review
  • Open Access
92 Citations
8,731 Views
16 Pages

Adhesins in Candida glabrata

  • Bea Timmermans,
  • Alejandro De Las Peñas,
  • Irene Castaño and
  • Patrick Van Dijck

20 May 2018

The human fungal pathogen Candida glabrata is causing more and more problems in hospitals, as this species shows an intrinsic antifungal drug resistance or rapidly becomes resistant when challenged with antifungals. C. glabrata only grows in the yeas...

  • Opinion
  • Open Access
216 Citations
12,291 Views
19 Pages

16 May 2018

As is true with animal species, plants also have an associated microflora including endophytes as well as microbes associated with the phyllosphere and rhizosphere (plant surfaces) and this is considered the plant microbiome. However, those organisms...

  • Article
  • Open Access
32 Citations
9,333 Views
15 Pages

16 May 2018

Fungal endophytes are diverse and widespread symbionts that occur in the living tissues of all lineages of plants without causing evidence of disease. Culture-based and culture-free studies indicate that they often are abundant in the leaves of woody...

  • Review
  • Open Access
46 Citations
13,073 Views
12 Pages

9 May 2018

Nodular lymphangitis, also known as sporotrichoid lymphocutaneous infections, is characterized by suppurative inflammatory nodules along the lymphatic vessels. This manifestation is classic of sporotrichosis, however, other infections such as nocardi...

  • Article
  • Open Access
18 Citations
9,481 Views
7 Pages

Sporotrichin Skin Test for the Diagnosis of Sporotrichosis

  • Alexandro Bonifaz,
  • Conchita Toriello,
  • Javier Araiza,
  • Max C. Ramírez-Soto and
  • Andrés Tirado-Sánchez

9 May 2018

Sporotrichosis is the most common implantation mycosis caused by several species of the Sporothrix schenckii complex. The gold standard for diagnosis is concerned with the isolation of the fungus; although, fresh examinations, staining, and biopsies...

  • Article
  • Open Access
4 Citations
5,812 Views
14 Pages

5 May 2018

Curvularia protuberata, an endophytic fungus in the Ascomycota, provides plants with thermotolerance only when it carries a mycovirus known as Curvularia thermotolerance virus (CThTV), and forms a three-way symbiotic relationship among these organism...

  • Article
  • Open Access
11 Citations
5,767 Views
11 Pages

Assessment of Genetic Diversity among Pleurotus spp. Isolates from Jordan

  • Hanan Aref Hasan,
  • Ahmad Mohamad Almomany,
  • Shireen Hasan and
  • Ayed M. Al-Abdallat

29 April 2018

Pleurotus is considered an important genus that belongs to the family Pleurotaceae and includes the edible King Oyster mushroom (Pleurotus eryngii). In the present study, 19 Pleurotus isolates were collected from two locations in the north of Jordan...

  • Article
  • Open Access
31 Citations
6,527 Views
11 Pages

Burden of Serious Fungal Infections in Argentina

  • Fernando O. Riera,
  • Juan P. Caeiro and
  • David W. Denning

24 April 2018

The number of fungal infections at any given time in Argentina is not known. Here we estimate the burden of serious fungal infections in Argentina for the first time. Specific population statistics were searched from multiple sources, local literatur...

  • Review
  • Open Access
84 Citations
8,874 Views
13 Pages

Lipid Biosynthesis as an Antifungal Target

  • Jiao Pan,
  • Cuiting Hu and
  • Jae-Hyuk Yu

20 April 2018

Lipids, commonly including phospholipids, sphingolipids, fatty acids, sterols, and triacylglycerols (TAGs), are important biomolecules for the viability of all cells. Phospholipids, sphingolipids, and sterols are important constituents of biological...

  • Review
  • Open Access
30 Citations
5,844 Views
11 Pages

An Overview of Sex Bias in C. neoformans Infections

  • Tiffany E. Guess,
  • Joseph A. Rosen and
  • Erin E. McClelland

18 April 2018

Cryptococcosis, a fungal disease arising from the etiologic agent Cryptococcus neoformans, sickens a quarter of a million people annually, resulting in over 180,000 deaths. Interestingly, males are affected by cryptococcosis more frequently than fema...

  • Article
  • Open Access
17 Citations
7,332 Views
12 Pages

10 April 2018

White-nose syndrome (WNS) is caused by Pseudogymnoascus destructans, a psychrophilic fungus that infects hibernating bats and has caused a serious decline in some species. Natural aroma compounds have been used to control growth of fungal food storag...

  • Article
  • Open Access
155 Citations
7,089 Views
9 Pages

Mucormycosis: Battle with the Deadly Enemy over a Five-Year Period in India

  • Jagdish Chander,
  • Mandeep Kaur,
  • Nidhi Singla,
  • R. P. S. Punia,
  • Surinder K. Singhal,
  • Ashok K. Attri,
  • Ana Alastruey-Izquierdo,
  • Alberto M. Stchigel,
  • Jose F. Cano-Lira and
  • Josep Guarro

6 April 2018

Mucormycosis is an emerging opportunistic fungal infection. Increasing immunocompromization, widespread use of antibacterial and antifungal agents (such as voriconazole prophylaxis), carcinomas, transplantation and lifestyle diseases such as diabetes...

  • Article
  • Open Access
9 Citations
4,598 Views
15 Pages

6 April 2018

Considering the significance in survival and virulence, we have made an attempt to understand modulations in the membrane and cell wall properties of Candida albicans hyphae induced by temperature (37 °C) and neutral pH and yeast form cells grown und...

  • Review
  • Open Access
47 Citations
9,081 Views
10 Pages

T2 Magnetic Resonance Assay: Overview of Available Data and Clinical Implications

  • Ioannis M. Zacharioudakis,
  • Fainareti N. Zervou and
  • Eleftherios Mylonakis

4 April 2018

Invasive candidiasis is a common healthcare-associated infection with a high mortality rate that can exceed 60% in cases of septic shock. Blood culture performance is far from ideal, due to the long time to positivity and suppression by antifungal ag...

  • Article
  • Open Access
26 Citations
5,694 Views
9 Pages

The Burden of Serious Fungal Infections in Cameroon

  • Christine E. Mandengue and
  • David W. Denning

30 March 2018

Fungal infections are frequent in Cameroon, and invasive fungal infections are sometimes detected, usually in HIV-infected patients. For these reasons, we have estimated the burden of fungal infections. Using published literature and population estim...

  • Review
  • Open Access
81 Citations
7,891 Views
12 Pages

24 March 2018

Plants are all inhabited by endophytic fungi in the interior of their tissues. The neem tree Azadirachta is an Indian lilac used for various therapeutic purposes in different forms of preparations. This plant hosts different types of endophytic fungi...

  • Article
  • Open Access
46 Citations
7,731 Views
13 Pages

Burden of Fungal Infections in Colombia

  • Carlos Arturo Alvarez-Moreno,
  • Jorge Alberto Cortes and
  • David W. Denning

21 March 2018

Data with respect to the epidemiological situation of fungal diseases in Colombia is scarce. Thus, the aim of this study is to estimate the burden of fungal infections. A population projection for 2017 from the Colombian Department for National Stati...

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J. Fungi - ISSN 2309-608X