Lung Epithelial Cell Line Immune Responses to Pneumocystis
Abstract
:1. Introduction
2. Lung Epithelium Cell Types
2.1. Alveolar Type 1 (AT1)
2.2. Alveolar Type 2 (AT2)
2.3. Club Cells
3. Continuous Cultured Lung Epithelial Cell Lines (Table 1)
3.1. A549
3.2. HAEo−
3.3. Murine Lung Epithelial Cell Line 12 (MLE-12)
3.4. Murine Lung Epithelial Cell Line 12 (MLE-15)
Cell Line | Source | Immune Response | Reference |
---|---|---|---|
A549 | Lung explant culture, epithelial-like (human) | CCL20 CXCL2 GM-CSF ICAM-1 IL-1a IL-6 IL-8 MCP-1 TNF-α TNFA IP2/3 | [19,42,43,45,46,48,53] |
1HAEo− | Airway epithelial (human) | IL-8 | [55] |
MLE-12 | Airway epithelial (mouse) | IL-6 | [60] |
MLE-15 | Airway epithelial (mouse) | MIP-2 | [26] |
4. Concluding Remarks
Author Contributions
Funding
Conflicts of Interest
References
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Kottom, T.J.; Carmona, E.M.; Limper, A.H. Lung Epithelial Cell Line Immune Responses to Pneumocystis. J. Fungi 2023, 9, 729. https://doi.org/10.3390/jof9070729
Kottom TJ, Carmona EM, Limper AH. Lung Epithelial Cell Line Immune Responses to Pneumocystis. Journal of Fungi. 2023; 9(7):729. https://doi.org/10.3390/jof9070729
Chicago/Turabian StyleKottom, Theodore J., Eva M. Carmona, and Andrew H. Limper. 2023. "Lung Epithelial Cell Line Immune Responses to Pneumocystis" Journal of Fungi 9, no. 7: 729. https://doi.org/10.3390/jof9070729