New Hydrogel Network Based on Alginate and a Spiroacetal Copolymer
Abstract
:1. Introduction
2. Results and Discussion
2.1. FTIR Spectra
2.2. SEM Studies
2.3. Thermal Degradation
2.4. Swelling Study
2.5. Release Study
3. Materials and Methods
3.1. Materials
3.2. Copolymer Synthesis
3.3. Bioconjugate Samples Preparation
3.4. Bioactive Compound Preparation
3.5. Characterization of PITAU–Alg Gels
3.5.1. FT–IR Spectra
3.5.2. SEM Studies
3.5.3. Thermal Analysis
3.5.4. The Swelling Studies
3.5.5. The Release Study
4. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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Sample | Degradation Stage | Tonset °C | Tpeak °C | W% | T20, °C | T40, °C | GS °C |
---|---|---|---|---|---|---|---|
S3 | I | 40 | 84 | 5.18 | 181 | 227 | 86 |
II | 145 | 185 | 29.28 | 190 | |||
III | 217 | 232 | 17.59 | 266 | |||
IV | 259 | 264 | 9.27 | 340 | |||
V | 309 | 325 | 16.13 | 460 | |||
residue | 22.55 | ||||||
S2 | I | 42 | 86 | 4.15 | 177 | 206 | |
II | 147 | 193 | 40.79 | ||||
III | 224 | 244 | 10.39 | ||||
IV | 252 | 259 | 9.67 | ||||
V | 309 | 347 | 16.26 | ||||
residue | 18.74 | ||||||
S1 | I | 34 | 71 | 6.52 | 172 | 203 | |
II | 144 | 189 | 39.56 | ||||
III | 224 | 243 | 11.28 | ||||
IV | 255 | 258 | 8.35 | ||||
V | 305 | 337 | 16.20 | ||||
residue | 18.09 |
Sample Name | n | Rn2 | k (min−n) | Rk2 |
---|---|---|---|---|
S1 | 0.4931 | 0.9976 | 0.0668 | 0.9971 |
S2 | 0.4055 | 0.9969 | 0.1209 | 0.9976 |
S3 | 0.5581 | 0.9982 | 0.0683 | 0.9989 |
Tested Samples | Gel Code | PITAU (g) | Alginate (g) |
---|---|---|---|
S1 | PITAU_Alg_3_1 | 6.50 | 2.15 |
S2 | PITAU_Alg_2_1 | 5.00 | 2.50 |
S3 | PITAU_Alg_1.5_1 | 4.00 | 2.65 |
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Sandu, A.E.; Nita, L.E.; Chiriac, A.P.; Tudorachi, N.; Rusu, A.G.; Pamfil, D. New Hydrogel Network Based on Alginate and a Spiroacetal Copolymer. Gels 2021, 7, 241. https://doi.org/10.3390/gels7040241
Sandu AE, Nita LE, Chiriac AP, Tudorachi N, Rusu AG, Pamfil D. New Hydrogel Network Based on Alginate and a Spiroacetal Copolymer. Gels. 2021; 7(4):241. https://doi.org/10.3390/gels7040241
Chicago/Turabian StyleSandu, Alina Elena, Loredana Elena Nita, Aurica P. Chiriac, Nita Tudorachi, Alina Gabriela Rusu, and Daniela Pamfil. 2021. "New Hydrogel Network Based on Alginate and a Spiroacetal Copolymer" Gels 7, no. 4: 241. https://doi.org/10.3390/gels7040241