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Volume 8
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10.3390/instruments8030038
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This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
Article

Improved Production of Novel Radioisotopes with Custom Energy Cyclone® Kiube

by
Sergio J. C. do Carmo
1,2,
Ângela C. B. Neves
1,2,
Eric Kral
3,
Jean-Michel Geets
3,
Benoit Nactergal
3,
Antero J. Abrunhosa
1,2 and
Francisco Alves
2,4,*
1
ICNAS Pharma, University of Coimbra, 3000-548 Coimbra, Portugal
2
CIBIT/ICNAS, Institute for Nuclear Sciences Applied to Health, University of Coimbra, 3000-548 Coimbra, Portugal
3
Ion Beam Applications, Chemin du Cyclotron, 3, 1348 Louvain-la-Neuve, Belgium
4
Polytechnic Institute of Coimbra, Coimbra Health School, 3045-093 Coimbra, Portugal
*
Author to whom correspondence should be addressed.
Instruments 2024, 8(3), 38; https://doi.org/10.3390/instruments8030038
Submission received: 16 May 2024 / Revised: 25 June 2024 / Accepted: 27 June 2024 / Published: 17 July 2024
(This article belongs to the Special Issue Selected Papers from the 15th Workshop of the European Cyclotron Network (CYCLEUR 2023))
Versions Notes

Abstract

The implementation of the Variable Energy (VE) feature in the previously fixed-energy IBA Cyclone® Kiube cyclotron is presented as an upgrade enabling the production of novel radioisotopes with improved radionuclidic purity and production yields. The possibility of easily decreasing the energy of the extracted proton beam, from 18 down to 13 MeV, allows us to avoid the use of degraders and/or thick target windows, thus preventing related beam current limitations. The immediate application of the Variable Energy feature is proven by presenting the improved results obtained for the production of 68Ga from the irradiation of liquid targets simultaneously in terms of radionuclidic purity and activity produced.
Keywords: cyclotron; variable energy; radionuclidic purity cyclotron; variable energy; radionuclidic purity

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MDPI and ACS Style

do Carmo, S.J.C.; Neves, Â.C.B.; Kral, E.; Geets, J.-M.; Nactergal, B.; Abrunhosa, A.J.; Alves, F. Improved Production of Novel Radioisotopes with Custom Energy Cyclone® Kiube. Instruments 2024, 8, 38. https://doi.org/10.3390/instruments8030038

AMA Style

do Carmo SJC, Neves ÂCB, Kral E, Geets J-M, Nactergal B, Abrunhosa AJ, Alves F. Improved Production of Novel Radioisotopes with Custom Energy Cyclone® Kiube. Instruments. 2024; 8(3):38. https://doi.org/10.3390/instruments8030038

Chicago/Turabian Style

do Carmo, Sergio J. C., Ângela C. B. Neves, Eric Kral, Jean-Michel Geets, Benoit Nactergal, Antero J. Abrunhosa, and Francisco Alves. 2024. "Improved Production of Novel Radioisotopes with Custom Energy Cyclone® Kiube" Instruments 8, no. 3: 38. https://doi.org/10.3390/instruments8030038

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