Effects of Oral Lactate Supplementation on Acid–Base Balance and Prolonged High-Intensity Interval Cycling Performance
Abstract
:1. Introduction
2. Materials and Methods
2.1. Participants
2.2. Experimental Design
2.3. Equipment and Measurements
2.4. Cardio Pulmonary Exercise Test (CPET)
2.5. Supplementation Strategy
2.6. Dietary Control
2.7. Exercise Protocol
2.8. Statistical Analysis
3. Results
3.1. Acid–Base Balance and Metabolic Measurements Pre and Post Supplementation
3.2. Performance Data
3.3. Heart Rate and Perceived Exertion
3.4. Acid–Base Balance and Metabolic Measurements during Exercise
3.5. Gastro-Intestinal Tolerance
4. Discussion
Strengths and Limitations
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Pre Supplementation | Post Supplementation | Δ | |
---|---|---|---|
Treatment | |||
Calcium Lactate | |||
[K+] mmol·−1 | 4.91 (4.62, 5.20) | 4.81 (4.62, 5.00) | −0.10 (−0.38, 0.18) |
[Na+] mmol·L−1 | 143 (142, 143) | 142 (141, 143) | −0.57 (−1.52, 0.38) |
[Cl−] mmol·L−1 | 107 (106, 108) | 105 (105, 106) | −2.07 (−2.77, −1.37) * |
[La−] mmol·L−1 | 2.14 (1.78, 2.50) | 1.86 (1.63, 2.10) | −0.27 (−0.59, 0.05) |
[Ca2+] mmol·L−1 | 1.24 (1.22, 1.26) | 1.26 (1.25, 1.28) | 0.02 (0.01, 0.03) |
pCO2 mm Hg | 41.31 (39.84, 42.77) | 42.68 (41.60, 43.76) | 1.37 (0.01, 2.73) |
[SID] mmol·L−1 | 39.44 (38.61, 40.28) | 41.14 (40.12, 42.15) | 1.69 (0.29, 3.10) * |
[HCO3−] mmol·L−1 | 25.79 (25.11, 26.46) | 26.68 (26.14, 27.22) | 0.89 (0.07, 1.71) * |
[H+] nmol·L−1 | 38.52 (37.29, 39.75) | 38.06 (36.98, 39.14) | −0.46 (−1.50, 0.59) |
[Glucose] mmol·L−1 | 5.11 (4.80, 5.43) | 5.11 (4.77, 5.46) | 0.00 (−0.48, 0.48) |
Placebo | |||
[K+] mmol·L−1 | 4.94 (4.60, 5.27) | 4.97 (4.76, 5.18) | 0.03 (−0.40, 0.47) |
[Na+] mmol·L−1 | 143 (142, 144) | 142 (141, 143) | −1.00 (−1.78, −0.22) |
[Cl−] mmol·L−1 | 107 (106, 108) | 106 (105, 107) | −0.64 (−1.42, 0.14) |
[La−] mmol·L−1 | 2.08 (1.76, 2.40) | 1.73 (1.42, 2.05) | −0.34 (−0.73, 0.04) |
[Ca2+] mmol·L−1 | 1.25 (1.23, 1.26) | 1.25 (1.24, 1.26) | 0.00 (−0.01, 0.02) |
pCO2 mm Hg | 41.88 (40.91, 42.86) | 42.70 (41.40, 44.00) | 0.82 (−0.45, 2.08) |
[SID] mmol·L−1 | 40.19 (39.16, 41.21) | 40.20 (39.21, 41.20) | 0.02 (−0.94, 0.97) |
[HCO3−] mmol·L−1 | 25.95 (25.40, 26.49) | 25.76 (25.21, 26.32) | −0.18 (−0.74, 0.38) |
[H+] nmol·L−1 | 38.62 (37.80, 39.44) | 39.30 (38.21, 40.39) | 0.68 (−0.51, 1.88) |
[Glucose] mmol·L−1 | 5.62 (5.27, 5.97) | 5.29 (5.01, 5.58) | −0.32 (−0.86, 0.21) |
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Bordoli, C.; Varley, I.; Sharpe, G.R.; Johnson, M.A.; Hennis, P.J. Effects of Oral Lactate Supplementation on Acid–Base Balance and Prolonged High-Intensity Interval Cycling Performance. J. Funct. Morphol. Kinesiol. 2024, 9, 139. https://doi.org/10.3390/jfmk9030139
Bordoli C, Varley I, Sharpe GR, Johnson MA, Hennis PJ. Effects of Oral Lactate Supplementation on Acid–Base Balance and Prolonged High-Intensity Interval Cycling Performance. Journal of Functional Morphology and Kinesiology. 2024; 9(3):139. https://doi.org/10.3390/jfmk9030139
Chicago/Turabian StyleBordoli, Claire, Ian Varley, Graham R. Sharpe, Michael A. Johnson, and Philip J. Hennis. 2024. "Effects of Oral Lactate Supplementation on Acid–Base Balance and Prolonged High-Intensity Interval Cycling Performance" Journal of Functional Morphology and Kinesiology 9, no. 3: 139. https://doi.org/10.3390/jfmk9030139