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Extended Abstract

Two-Way Relationship between Diabetes and Periodontal Disease: A Reality or a Paradigm? †

by
Dorina Lauritano
1,*,
Giulia Moreo
1,
Francesco Carinci
2,
Alberta Lucchese
3,
Dario di Stasio
3,
Fedora della Vella
4 and
Massimo Petruzzi
4
1
Department of Medicine and Surgery, Centre of Neuroscience, University of Milano-Bicocca, 20126 Milan, Italy
2
Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, 44121 Ferrara, Italy
3
Multidisciplinary Department of Medical-Surgical and Dental Specialties, University of Campania—Luigi Vanvitelli, 80138 Naples, Italy
4
Interdisciplinary Department of Medicine, University of Bari, 70121 Bari, Italy
*
Author to whom correspondence should be addressed.
†
Presented at the XV National and III International Congress of the Italian Society of Oral Pathology and Medicine (SIPMO), Bari, Italy, 17–19 October 2019.
Proceedings 2019, 35(1), 15; https://doi.org/10.3390/proceedings2019035015
Published: 10 December 2019
(This article belongs to the Proceedings of The XV National and III International Congress of the Italian Society of Oral Pathology and Medicine)
Versions Notes
Diabetes mellitus (DM) and periodontal disease (PD) are both chronic diseases.
From one side, DM have an adverse effect on PD, and on the other side PD may influence DM. Systemic therapy of DM with glycaemic control, affects the progress of PD. Reversely treatment of PD combined with the administration of systemic antibiotics seems to have a double effect on diabetic patients reducing the periodontal infection and improving the glycaemic control [1,2].
Inflammation, altered host responses, altered tissue homeostasis are common characteristic of both DM and PD. The potential common pathophysiologic pathways of direct or reverse relationship of DM and PD are still unknown and further in vitro and in vivo studies are needed to explore this relationship [3,4].

Conflicts of Interest

The authors declare no conflict of interest.

References

  1. Centers for Disease Control and Prevention. National Diabetes Fact Sheet: National Estimates and General Information on Diabetes and Prediabetes in the United States, 2011; Department of Health and Human Services, Centers for Disease Control and Prevention: Atlanta, GA, USA, 2011. Available online: http://www.cdc.gov/diabetes/pubs/pdf/ndfs_2011. pdf (accessed on 6 January 2013).
  2. Chen, L.; Magliano, D.J.; Zimmet, P.Z. The worldwide epidemiology of type 2 diabetes mellitus–present and future perspectives. Nat. Rev. Endocrinol. 2012, 8, 228–236. [Google Scholar] [CrossRef]
  3. Albandar, J.M.; Rams, T.E. Global epidemiology of periodontal diseases: An overview. Periodontol. 2000 2002, 29, 7–10. [Google Scholar] [CrossRef] [PubMed]
  4. Monnier, V.M.; Mustata, G.T.; Biemel, K.L.; Reihl, O.; Lederer, M.O.; Zhenyu, D.A.I.; Sell, D.R. Cross-linking of the extracellular matrix by the Maillard reaction in aging and diabetes: An update on “a puzzle nearing resolution”. Ann. N. Y. Acad. Sci. 2005, 1043, 533–544. [Google Scholar] [CrossRef] [PubMed]
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MDPI and ACS Style

Lauritano, D.; Moreo, G.; Carinci, F.; Lucchese, A.; Stasio, D.d.; Vella, F.d.; Petruzzi, M. Two-Way Relationship between Diabetes and Periodontal Disease: A Reality or a Paradigm? Proceedings 2019, 35, 15. https://doi.org/10.3390/proceedings2019035015

AMA Style

Lauritano D, Moreo G, Carinci F, Lucchese A, Stasio Dd, Vella Fd, Petruzzi M. Two-Way Relationship between Diabetes and Periodontal Disease: A Reality or a Paradigm? Proceedings. 2019; 35(1):15. https://doi.org/10.3390/proceedings2019035015

Chicago/Turabian Style

Lauritano, Dorina, Giulia Moreo, Francesco Carinci, Alberta Lucchese, Dario di Stasio, Fedora della Vella, and Massimo Petruzzi. 2019. "Two-Way Relationship between Diabetes and Periodontal Disease: A Reality or a Paradigm?" Proceedings 35, no. 1: 15. https://doi.org/10.3390/proceedings2019035015

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