Proceedings

2 pages, 144 KiB

Open AccessAbstract

Delineating Humoral and Cellular Immune Responses Induced by a Peptide-Based Vaccine for Protection Against Streptococcus pyogenes

by Despena Vedis, Ailin Lepletier, Victoria Ozberk, Simone Reynolds, Ainslie Calcutt, Darrell Bessette, Michael F. Good and Manisha Pandey

Proceedings 2025, 124(1), 19; https://doi.org/10.3390/proceedings2025124019 - 18 Aug 2025

Abstract

Despite the substantial burden of Streptococcus pyogenes infections and their associated sequalae, there is currently no Strep A vaccine [...] Full article

(This article belongs to the Proceedings of The 22nd Lancefield International Symposium on Streptococci and Streptococcal Diseases (LISSSD 2025))

2 pages, 120 KiB

Open AccessAbstract

GAS Regulation of Zinc Homeostasis During Skin and Soft Tissue Infection

by Reid Wilkening, Lindsey Burcham, Laura Cook and Alexander Horswill

Proceedings 2025, 124(1), 17; https://doi.org/10.3390/proceedings2025124017 - 15 Aug 2025

Abstract

Streptococcus pyogenes (Group A Streptococcus, GAS) is an enigmatic human-restricted pathobiont, capable of both colonization and infection [...] Full article

(This article belongs to the Proceedings of The 22nd Lancefield International Symposium on Streptococci and Streptococcal Diseases (LISSSD 2025))

2 pages, 133 KiB

Open AccessAbstract

Incidence of Invasive Group A Streptococcal Infections and Comparison of emm Types from Carriage, Pharyngitis, and Invasive Infections in Indigenous Communities in the Southwest United States

by Catherine G. Sutcliffe, Victoria M. Sergent, Joyselynn Pitalua, Sopio Chochua, Christopher J. Gregory, Chloe Hurley, Zhongya Li, Saundra Mathis, Lesley McGee, Jennifer Onukwube Okaro, Theresa Tran, Robert Weatherholtz and Laura L. Hammitt

Proceedings 2025, 124(1), 16; https://doi.org/10.3390/proceedings2025124016 - 15 Aug 2025

Abstract

Background: Indigenous communities are disproportionately affected by group A Streptococcus (GAS) infections [...] Full article

(This article belongs to the Proceedings of The 22nd Lancefield International Symposium on Streptococci and Streptococcal Diseases (LISSSD 2025))

2 pages, 120 KiB

Open AccessAbstract

Differential Immune Response in Children to Throat Specialist Versus Generalist Group A Streptococci

by Debra E. Bessen, Jeanne M. DiChiara, Freda F. Tei, Ji Ho Lee, Ari Shechtman, Shivaleela Keerthy, Suchitra Bhattacharjee, Luiza Karrer and Sang Ho Lee

Proceedings 2025, 124(1), 11; https://doi.org/10.3390/proceedings2025124011 - 15 Aug 2025

Abstract

Background: The antigenic heterogeneity of GAS poses a challenge for vaccine design [...] Full article

(This article belongs to the Proceedings of The 22nd Lancefield International Symposium on Streptococci and Streptococcal Diseases (LISSSD 2025))

2 pages, 123 KiB

Open AccessAbstract

The Veituberi Approach Transforming RHD Through Patient Leadership and Lived Experience

by Erini Kala, Marika Yalimaiwai, Maria Mow, Jimaima Kailawadoko-Matanaicake and Joseph Kado

Proceedings 2025, 124(1), 14; https://doi.org/10.3390/proceedings2025124014 - 14 Aug 2025

Abstract

Rheumatic heart disease (RHD), a complication of untreated Strep A infections, is a major global health concern [...] Full article

(This article belongs to the Proceedings of The 22nd Lancefield International Symposium on Streptococci and Streptococcal Diseases (LISSSD 2025))

2 pages, 120 KiB

Open AccessAbstract

Contemporary Clinical Characteristics and Presentation of ARF Globally

by Omeir Aziz, Tehmina Kazmi, Humera Javed, Ndate Fall and Masood Sadiq

Proceedings 2025, 124(1), 15; https://doi.org/10.3390/proceedings2025124015 - 13 Aug 2025

Abstract

Background: Acute rheumatic fever (ARF) is a significant public health concern in resource-limited settings, but its clinical presentation remains inadequately described [...] Full article

(This article belongs to the Proceedings of The 22nd Lancefield International Symposium on Streptococci and Streptococcal Diseases (LISSSD 2025))

2 pages, 120 KiB

Open AccessAbstract

Pacific Adaptation of Tools for Implementing Rheumatic Heart Disease Control Programmes (TIPs)

by Jessica N. Daw, Rosemary Wyber and Joseph H. Kado

Proceedings 2025, 124(1), 13; https://doi.org/10.3390/proceedings2025124013 - 13 Aug 2025

Abstract

In 2013, the framework ‘Tools for Implementing Rheumatic Heart Disease (RHD) Control Programmes’ (TIPs) was published [...] Full article

(This article belongs to the Proceedings of The 22nd Lancefield International Symposium on Streptococci and Streptococcal Diseases (LISSSD 2025))

2 pages, 135 KiB

Open AccessAbstract

Prevalence, Risk Factors, and Strain Distribution of Group A Streptococcus Carriage Among Indigenous Children in the Southwest United States

by Catherine G. Sutcliffe, Victoria M. Sergent, Joyselynn Pitalua, Sopio Chochua, Christopher J. Gregory, Chloe Hurley, Zhongya Li, Saundra Mathis, Lesley McGee, Jennifer Onukwube Okaro, Theresa Tran, Robert Weatherholtz and Laura L. Hammitt

Proceedings 2025, 124(1), 12; https://doi.org/10.3390/proceedings2025124012 - 13 Aug 2025

Abstract

Background [...] Full article

(This article belongs to the Proceedings of The 22nd Lancefield International Symposium on Streptococci and Streptococcal Diseases (LISSSD 2025))

9 pages, 237 KiB

Open AccessProceeding Paper

Jean Piaget and Objectivity—Genetic Epistemology’s Place in a View from Nowhere

by Mark A. Winstanley

Proceedings 2025, 126(1), 1; https://doi.org/10.3390/proceedings2025126001 - 13 Aug 2025

Abstract

Science pursues objectivity. According to Thomas Nagel, “we must get outside of ourselves, and view the world from nowhere within it” is the most natural expression of this goal. However, we cannot literally get outside of ourselves; realistically, we can only hope to [...] Read more.

Science pursues objectivity. According to Thomas Nagel, “we must get outside of ourselves, and view the world from nowhere within it” is the most natural expression of this goal. However, we cannot literally get outside of ourselves; realistically, we can only hope to achieve a more detached conception by relying “less and less on certain individual aspects, and more and more on something else, less individual, which is also part of us”. This “self-transcendent conception should ideally explain (1) what the world is like; (2) what we are like; (3) why the world appears to beings like us in certain respects as it is and in certain respects as it isn’t; (4) how beings like us can arrive at such a conception.” The natural and human sciences address (1)–(3), but the last condition is rarely met, according to Nagel. In this paper, I argue that the genetic epistemology conceived by Jean Piaget as a science of the growth of knowledge explains how beings like us meet condition (4). Full article

2 pages, 119 KiB

Open AccessAbstract

Addressing Rheumatic Heart Disease in the Pacific

by Joseph H. Kado, Jessica N. Daw, Christine Everest and Rosemary Wyber

Proceedings 2025, 124(1), 7; https://doi.org/10.3390/proceedings2025124007 - 12 Aug 2025

Abstract

Background/Purpose: Pacific leaders have articulated addressing rheumatic heart disease (RHD) as a Pacific health priority [...] Full article

(This article belongs to the Proceedings of The 22nd Lancefield International Symposium on Streptococci and Streptococcal Diseases (LISSSD 2025))

8 pages, 467 KiB

Open AccessProceeding Paper

Role of a Natural Antioxidant in the Secondary Shelf Life of Ready-to-Use Meat Pâté

by Beatrice Sordini, Sonia Esposto, Arianna Bonucci, Ilenia Dottori, Luigi Daidone, Stefania Urbani, Gianluca Veneziani, Roberto Selvaggini, Maurizio Servili, Davide Nucciarelli and Agnese Taticchi

Proceedings 2025, 119(1), 10; https://doi.org/10.3390/proceedings2025119010 - 11 Aug 2025

Abstract

By-products from the agro-food industry can be natural ingredients for reformulating traditional foods, enhancing quality, extending secondary shelf life (SSL), and reducing food waste. This study evaluates the impact of an olive vegetation water phenolic extract (OVWPE) at two concentrations on ready-to-use meat [...] Read more.

By-products from the agro-food industry can be natural ingredients for reformulating traditional foods, enhancing quality, extending secondary shelf life (SSL), and reducing food waste. This study evaluates the impact of an olive vegetation water phenolic extract (OVWPE) at two concentrations on ready-to-use meat pâté (MP1 and MP2) under simulated retail storage. We evaluated the phenolic composition, volatile compounds, antioxidant activity, and sensory quality of the OVWPE-added pâté and compared it to the control sample (CTRL; without antioxidant). Results indicated that OVWPE minimized oxidation products, enhancing lipid stability, and also reduced the formation of C₆–C₉ aldehydes linked to rancid off-flavor. Without sensory defects, the OVWPE pâtés showed higher antioxidant activity and α-tocopherol content than the CTRL. OVWPE appears to be a promising antioxidant of natural origin for food formulations, supporting SSL extension and food waste reduction. Full article

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13 pages, 244 KiB

Open AccessConference Report

Proceedings of the 13th Alcohol Hangover Research Group Meeting in Dresden, Germany

by Emina Išerić, Anne S. Boogaard, Gillian Bruce, Jacqueline M. Iversen, Analia Karadayian, Andy J. Kim, Darren Kruisselbrink, Marlou Mackus, Agnese Merlo, Ann-Kathrin Stock, Jakub Urbański, Benthe R. C. van der Weij and Joris C. Verster

Proceedings 2025, 122(1), 2; https://doi.org/10.3390/proceedings2025122002 - 11 Aug 2025

Abstract

These proceedings summarize the presentations of the 13th Alcohol Hangover Research Group meeting held 20–22 April 2023 in Dresden, Germany. The purpose of this annual meeting is to discuss current research on the causes, consequences and treatment of alcohol hangover, to network, and [...] Read more.

These proceedings summarize the presentations of the 13th Alcohol Hangover Research Group meeting held 20–22 April 2023 in Dresden, Germany. The purpose of this annual meeting is to discuss current research on the causes, consequences and treatment of alcohol hangover, to network, and to establish future research collaborations. Various topics of interest were presented and discussed, including the impact of anxiety and personality on susceptibility for experiencing hangovers, sleep, the impact of the COVID-19 pandemic, the role of inflammation and alcohol metabolism in the pathology of alcohol hangover, novel treatments, and the changing regulatory landscape for hangover solutions. Full article

2 pages, 133 KiB

Open AccessAbstract

Genomic Characterization and Classification of Streptococcus oralis Using Next-Generation Sequencing

by Ghiwa Chalhoub, Rayane Adam, Carmen Adam, Carni Boujanian, Rita Menhem, Peter Saba, Nancy Al Boustany, Charbel Al Khoury, Edmond Abboud, Rodrigue Saad and Sima Tokajian

Proceedings 2025, 124(1), 10; https://doi.org/10.3390/proceedings2025124010 - 8 Aug 2025

Abstract

Streptococcus oralis is an alpha-hemolytic, Gram-positive bacterium from the viridans group streptococci (VGS) [...] Full article

(This article belongs to the Proceedings of The 22nd Lancefield International Symposium on Streptococci and Streptococcal Diseases (LISSSD 2025))

2 pages, 127 KiB

Open AccessAbstract

Whole-Genome Sequencing Reveals the Genetic Divergence of the emm1-2 Genotype Prevalent in India from the Globally Prevalent emm1, Supporting Its Classification as a Distinct Genotype

by Vivek Sagar, Gurwinder Kaur, Anuradha Chakraborti and Rajesh Kumar

Proceedings 2025, 124(1), 9; https://doi.org/10.3390/proceedings2025124009 - 8 Aug 2025

Abstract

The significant genetic diversity among Group A Streptococcal (GAS) strains isolated from various geographical regions presents serious challenges for treatment and vaccine development strategies [...] Full article

(This article belongs to the Proceedings of The 22nd Lancefield International Symposium on Streptococci and Streptococcal Diseases (LISSSD 2025))

2 pages, 131 KiB

Open AccessAbstract

Parenteral Vaccination with a Super Immunogen Targeting M-Protein Provides Unprecedented Protection Against Group A Streptococcus (StrepA) Respiratory Infections

by Victoria Ozberk, Christie Short, Ailin Lepletier, Ainslie Calcutt, Khushi Jain, Simone Reynolds, Aroon Supramaniam, Jamie-lee Mills, Jessica Dooley, Jacqualine Kaden, Michael F. Good and Manisha Pandey

Proceedings 2025, 124(1), 8; https://doi.org/10.3390/proceedings2025124008 - 8 Aug 2025

Abstract

Rheumatic heart disease (RHD) is a devastating consequence of group A streptococcus (StrepA) infections, being associated with 15 [...] Full article

(This article belongs to the Proceedings of The 22nd Lancefield International Symposium on Streptococci and Streptococcal Diseases (LISSSD 2025))

614 KiB

Open AccessProceeding Paper

An Evaluative Approach of Corporate Sustainability in Agrifood System

by Luisa Sturiale, Carla Zarbà, Mariarita Cammarata, Agata Matarazzo and Alessandro Scuderi

Proceedings 2025, 117(1), 34; https://doi.org/10.3390/proceedings2025117034 - 7 Aug 2025

Abstract

In recent decades, companies have developed innovative sustainable business management models capable of integrating green, resilient and inclusive approaches. Recently, partly as a result of EU and international regulatory guidelines, Corporate Sustainability (CS) is becoming more diffused in business models through which companies [...] Read more.

In recent decades, companies have developed innovative sustainable business management models capable of integrating green, resilient and inclusive approaches. Recently, partly as a result of EU and international regulatory guidelines, Corporate Sustainability (CS) is becoming more diffused in business models through which companies have attempted to integrate the three dimensions of sustainability (economic, social and environmental). The objective of this research is to analyze the processes of integrating CS into business management and the related online communication of implemented sustainable actions through an integrated methodological approach based on the analysis of the websites of Italian agribusinesses, using the “7S” method of analysis, supplemented by specific Focus Groups to acquire qualitative information directly from a sample of companies to analyze the motivations for companies to move toward sustainable actions. In the paper, the methodological approach will be proposed, as the research is in progress and includes, among the objectives, the identification of key drivers and the implementation of strategies for CS in line with the SDGs related to the corporate ecosystem. Full article

(This article belongs to the Proceedings of 11th International Conference on Information and Communication Technologies in Agriculture, Food and Environment (HAICTA 2024), Volume II)

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5 pages, 814 KiB

Open AccessProceeding Paper

Numerical Investigation of Low-Reynolds-Number Flow in Double Schwarz-D TPMS Structure

by Kasimhussen Vhora, Dominique Thévenin, Gábor Janiga and Kai Sundmacher

Proceedings 2025, 121(1), 14; https://doi.org/10.3390/proceedings2025121014 - 7 Aug 2025

Abstract

This study presents a comprehensive computational fluid dynamics (CFD) analysis of airflow in double Schwarz-D Triply Periodic Minimal Surface (TPMS) structures under laminar steady-flow conditions. The pressure drop characteristics of these structures are investigated using representative elementary volume (REV)-scale CFD simulations. Two porosities, [...] Read more.

This study presents a comprehensive computational fluid dynamics (CFD) analysis of airflow in double Schwarz-D Triply Periodic Minimal Surface (TPMS) structures under laminar steady-flow conditions. The pressure drop characteristics of these structures are investigated using representative elementary volume (REV)-scale CFD simulations. Two porosities, 58% and 80%, are analyzed to evaluate the influence of porosity on the flow characteristics and pressure drop. The results reveal that an increase in porosity significantly affects the hydraulic Reynolds number. For the 58% porosity structure, laminar flow is observed at hydraulic Reynolds numbers of 50 or lower, whereas the 80% porosity structure maintains laminar flow at Reynolds numbers up to 180. These findings provide valuable insights into the design and optimization of double Schwarz-D TPMS structures for engineering applications, particularly in scenarios requiring efficient fluid transport with controlled pressure drops. Full article

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2 pages, 115 KiB

Open AccessAbstract

A Molecular Epidemiology of Invasive Group A Streptococcus (iGAS) Infection Detected Within the Hunter New England Local Health District (HNELHD) of New South Wales (NSW), Australia from 2007 to 2017

by Pappu K. Mandal, Trent A. J. Butler, Emily Green, Kirsten M. Williamson, Sebastiaan Van Hal and Hemalatha Varadhan

Proceedings 2025, 124(1), 6; https://doi.org/10.3390/proceedings2025124006 - 7 Aug 2025

Abstract

Invasive Group A Streptococcal infection (iGAS) is an uncommon but serious infection with reported case fatality rates of up to 15% [...] Full article

(This article belongs to the Proceedings of The 22nd Lancefield International Symposium on Streptococci and Streptococcal Diseases (LISSSD 2025))

2 pages, 109 KiB

Open AccessAbstract

The Emerging Role of Biomarker-Driven Diagnostics in Post-Streptococcal Glomerulonephritis

by Tawakaltu Abdulrasheed-Adeleke, Muhammad Haruna Garba and Aliyu Evuti Haruna

Proceedings 2025, 124(1), 5; https://doi.org/10.3390/proceedings2025124005 - 6 Aug 2025

Abstract

Post-streptococcal glomerulonephritis (PSGN) is an immune-mediated kidney disease that occurs after infection with Streptococcus pyogenes (Group A Streptococcus, GAS) [...] Full article

(This article belongs to the Proceedings of The 22nd Lancefield International Symposium on Streptococci and Streptococcal Diseases (LISSSD 2025))

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