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Abstract

Effect of Manuka Honey Eye Drops among Patients Diagnosed with Adenoviral Keratoconjunctivitis in The Gaza Strip †

by
Aysha F. Alagha
1,*,
Riad El-Qidra
2,
Marwan O. Jalambo
3 and
Bassam Alhabibi
3
1
Ministry of Education, Gaza P.O. Box 576, Palestine
2
Faculty of Pharmacy, Al-Azhar University Gaza (AUG), Gaza P.O. Box 405, Palestine
3
Nutrition Sciences and Public Health Program, Palestine Technical College, Deir Al-Balah P.O. Box 6037, Palestine
*
Author to whom correspondence should be addressed.
†
Presented at the Second International Conference on Applied Medical Sciences 2023 (ICAMS-II) and the International Conference on Enhancing Clinical Nutrition in Palestine (ECNAD), Gaza, Palestine, 14–16 March 2023.
Proceedings 2023, 88(1), 5; https://doi.org/10.3390/proceedings2023088005
Published: 28 July 2023
Versions Notes

Abstract

:
A large amount of research has established that honey has potent antibacterial activity. However, the sensitivity of infection-causing viral species to honey has been scarcely studied. This study was designed to evaluate the effect of Manuka Honey eye drops among patients diagnosed with adenovirus conjunctivitis. Sixty-one patients with adenovirus keratoconjunctivitis were recruited in this quasi-experimental, multi-center study. All eligible subjects were randomly categorized into two groups: the first group was the control group, which was treated with steroids (conventional treatment), while the second group was the intervention group, which was treated with Manuka Honey drops at a concentration of 16.5% four times per day with conventional treatment (steroids). Symptoms in both groups, as well as the total ocular symptom score (TOSS), were compared. The results of the experimental group demonstrate the effectiveness of Manuka Honey eye drops in relieving symptoms of adenovirus keratoconjunctivitis. The findings of this study indicated that there was a statistically significant difference between the groups in terms of the number of days they had adenovirus keratoconjunctivitis (p > 0.001). Also, the mean itchy, redness, and tearing scores on day 4 among the patients in the intervention group were less than those in the control group (p > 0.001). In addition, the TOSS score on day 4 and day 8 among the patients in the intervention group was extremely lower than those in the control group (p > 0.001). The results of this study have shown important improvements in the symptoms of adenovirus keratoconjunctivitis. Our findings showed positive results within a short period, meaning that our results suggest that Manuka honey eye drops show promise as an adjunct natural treatment and that prescribing them in conjunction with conventional steroids can help alleviate the symptoms of adenovirus keratoconjunctivitis.

Author Contributions

Conceptualization, A.F.A. and M.O.J.; methodology, M.O.J., B.A. and R.E.-Q.; software, M.O.J.; validation, A.F.A., M.O.J. and R.E.-Q. and B.A.; formal analysis, M.O.J.; investigation, M.O.J.; resources, A.F.A.; data curation, A.F.A., B.A. and M.O.J.; writing—original draft preparation, A.F.A.; writing—review and editing, A.F.A., M.O.J. and R.E.-Q.; visualization, A.F.A. and M.O.J.; supervision, M.O.J., B.A. and R.E.-Q.; project administration, M.O.J. and R.E.-Q.; All authors have read and agreed to the published version of the manuscript.

Funding

This research received no external funding just manuka honey eye drops received free of charge from Optimel company.

Institutional Review Board Statement

Not applicable.

Informed Consent Statement

Informed consent was obtained from all study sample involved in the study.

Data Availability Statement

Not applicable.

Conflicts of Interest

The authors declare no conflict of interest.
Disclaimer/Publisher’s Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content.

Share and Cite

MDPI and ACS Style

Alagha, A.F.; El-Qidra, R.; Jalambo, M.O.; Alhabibi, B. Effect of Manuka Honey Eye Drops among Patients Diagnosed with Adenoviral Keratoconjunctivitis in The Gaza Strip. Proceedings 2023, 88, 5. https://doi.org/10.3390/proceedings2023088005

AMA Style

Alagha AF, El-Qidra R, Jalambo MO, Alhabibi B. Effect of Manuka Honey Eye Drops among Patients Diagnosed with Adenoviral Keratoconjunctivitis in The Gaza Strip. Proceedings. 2023; 88(1):5. https://doi.org/10.3390/proceedings2023088005

Chicago/Turabian Style

Alagha, Aysha F., Riad El-Qidra, Marwan O. Jalambo, and Bassam Alhabibi. 2023. "Effect of Manuka Honey Eye Drops among Patients Diagnosed with Adenoviral Keratoconjunctivitis in The Gaza Strip" Proceedings 88, no. 1: 5. https://doi.org/10.3390/proceedings2023088005

APA Style

Alagha, A. F., El-Qidra, R., Jalambo, M. O., & Alhabibi, B. (2023). Effect of Manuka Honey Eye Drops among Patients Diagnosed with Adenoviral Keratoconjunctivitis in The Gaza Strip. Proceedings, 88(1), 5. https://doi.org/10.3390/proceedings2023088005

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