Preparation and Hydrolytic Degradation of Hydroxyapatite-Filled PLGA Composite Microspheres
Abstract
:1. Introduction
2. Materials and Methods
2.1. Materials
2.2. Synthesis of PLGA
2.3. Formation of Microspheres Based on PLGA
2.4. Study of Hydrolytic Degradation of PLGA
3. Results and Discussion
4. Conclusions
Author Contributions
Funding
Data Availability Statement
Conflicts of Interest
References
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Polymer | Yield, % | Ratio of Monomers x:y *, mol% | Mn ** | Mw/Mn ** | |
---|---|---|---|---|---|
Calculated | Determined | ||||
1 | 86 | 100:0 | 100:0 | 28,500 | 1.7 |
2 | 88 | 90:10 | 88:12 | 29,000 | 1.7 |
3 | 90 | 75:25 | 73:24 | 31,000 | 1.8 |
4 | 85 | 70:30 | 68:32 | 33,000 | 1.9 |
5 | 89 | 50:50 | 42:58 | - | - |
6 | 91 | 25:75 | 23:77 | - | - |
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Istratov, V.; Gomzyak, V.; Baranov, O.; Markova, G.; Mezhuev, Y.; Vasnev, V. Preparation and Hydrolytic Degradation of Hydroxyapatite-Filled PLGA Composite Microspheres. J. Compos. Sci. 2023, 7, 346. https://doi.org/10.3390/jcs7090346
Istratov V, Gomzyak V, Baranov O, Markova G, Mezhuev Y, Vasnev V. Preparation and Hydrolytic Degradation of Hydroxyapatite-Filled PLGA Composite Microspheres. Journal of Composites Science. 2023; 7(9):346. https://doi.org/10.3390/jcs7090346
Chicago/Turabian StyleIstratov, Vladislav, Vitaliy Gomzyak, Oleg Baranov, Galy Markova, Yaroslav Mezhuev, and Valerii Vasnev. 2023. "Preparation and Hydrolytic Degradation of Hydroxyapatite-Filled PLGA Composite Microspheres" Journal of Composites Science 7, no. 9: 346. https://doi.org/10.3390/jcs7090346