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Volume 77
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10.5603/ARM.27807
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Advances in Respiratory Medicine is published by MDPI from Volume 90 Issue 4 (2022). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Via Medica.
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Review

Methods of Estimating Concentration of the D-Dimers Used in Venous Thromboembolism Diagnosis

by
Bartłomiej Walczak
1,
Urszula Demkow
1,* and
Anna Fijałkowska
2
1
Zakład Diagnostyki Laboratoryjnej i Immunologii Klinicznej Warszawskiego Uniwersytetu Medycznego, 01-138 Warsaw, Poland
2
Klinika Chorób Wewnętrznych Klatki Piersiowej Instytutu Gruźlicy i Chorób Płuc w Warszawie, 01-138 Warsaw, Poland
*
Author to whom correspondence should be addressed.
Adv. Respir. Med. 2009, 77(3), 264-270; https://doi.org/10.5603/ARM.27807
Submission received: 27 March 2008 / Revised: 23 April 2009 / Accepted: 23 April 2009 / Published: 23 April 2009

Abstract

D-dimers (DD) are final products of stabilized fibrin degradation process. Elevated level of DD indicates parallel activation of both coagulation and fibrinolysis. D-dimers play important role in the diagnosis of deep vein thrombosis and pulmonary embolism. All diagnostic methods detecting DD are based on monoclonal antibodies. There are three basic techniques used to measure DD: latex agglutination, full blood agglutination and immunoenzymatic methods. Nowadays new methods based on in vivo detection of DD using antibodies labeled with technetium are under clinical evaluation.
Keywords: D-dimers; laboratory diagnosis; pulmonary embolism; deep vein thrombosis D-dimers; laboratory diagnosis; pulmonary embolism; deep vein thrombosis

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MDPI and ACS Style

Walczak, B.; Demkow, U.; Fijałkowska, A. Methods of Estimating Concentration of the D-Dimers Used in Venous Thromboembolism Diagnosis. Adv. Respir. Med. 2009, 77, 264-270. https://doi.org/10.5603/ARM.27807

AMA Style

Walczak B, Demkow U, Fijałkowska A. Methods of Estimating Concentration of the D-Dimers Used in Venous Thromboembolism Diagnosis. Advances in Respiratory Medicine. 2009; 77(3):264-270. https://doi.org/10.5603/ARM.27807

Chicago/Turabian Style

Walczak, Bartłomiej, Urszula Demkow, and Anna Fijałkowska. 2009. "Methods of Estimating Concentration of the D-Dimers Used in Venous Thromboembolism Diagnosis" Advances in Respiratory Medicine 77, no. 3: 264-270. https://doi.org/10.5603/ARM.27807

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