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Volume 83
Issue 1
10.5603/PiAP.2015.0007
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Advances in Respiratory Medicine is published by MDPI from Volume 90 Issue 4 (2022). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Via Medica.
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Case Report

Leflunomide-Induced Acute Interstitial Pneumonia in a Patient Treated for Rheumatoid Arthritis

by
Marta Maskey-Warzęchowska
1,
Krzysztof Karwat
1,*,
Benedykt Szczepankiewicz
2,
Renata Langfort
3,
Małgorzata Szołkowska
3 and
Ryszarda Chazan
1
1
Department of Internal Medicine, Pneumonology and Allergology, Medical University of Warsaw, 02-097 Warszawa, Poland
2
Department of Pathology, Medical University of Warsaw, Warsaw, Poland
3
Department of Pathology, Institute for Tuberculosis and Lung Diseases, Warsaw, Poland
*
Author to whom correspondence should be addressed.
Adv. Respir. Med. 2015, 83(1), 50-54; https://doi.org/10.5603/PiAP.2015.0007
Submission received: 6 May 2014 / Revised: 8 January 2015 / Accepted: 8 January 2015 / Published: 8 January 2015

Abstract

Leflunomide is a disease-modifying anti-rheumatic drug that is used in patients with rheumatoid arthritis (RA), who do not respond well to standard RA treatment. Leflunomide therapy may, however, be related with significant pulmonary complications in predisposed individuals. We present a patient with RA treated with leflunomide, in whom leflunomide lung injury had a fatal outcome. Potential risk factors for pulmonary complications of leflunomide treatment and the management of patients with leflunomide lung injury are discussed.
Keywords: interstitial pneumonia; rheumatoid arthritis; leflunomide interstitial pneumonia; rheumatoid arthritis; leflunomide

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MDPI and ACS Style

Maskey-Warzęchowska, M.; Karwat, K.; Szczepankiewicz, B.; Langfort, R.; Szołkowska, M.; Chazan, R. Leflunomide-Induced Acute Interstitial Pneumonia in a Patient Treated for Rheumatoid Arthritis. Adv. Respir. Med. 2015, 83, 50-54. https://doi.org/10.5603/PiAP.2015.0007

AMA Style

Maskey-Warzęchowska M, Karwat K, Szczepankiewicz B, Langfort R, Szołkowska M, Chazan R. Leflunomide-Induced Acute Interstitial Pneumonia in a Patient Treated for Rheumatoid Arthritis. Advances in Respiratory Medicine. 2015; 83(1):50-54. https://doi.org/10.5603/PiAP.2015.0007

Chicago/Turabian Style

Maskey-Warzęchowska, Marta, Krzysztof Karwat, Benedykt Szczepankiewicz, Renata Langfort, Małgorzata Szołkowska, and Ryszarda Chazan. 2015. "Leflunomide-Induced Acute Interstitial Pneumonia in a Patient Treated for Rheumatoid Arthritis" Advances in Respiratory Medicine 83, no. 1: 50-54. https://doi.org/10.5603/PiAP.2015.0007

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