Osteology, Volume 6, Issue 1 (March 2026) – 5 articles

Background/Objectives: The anatomical variability of the human foot represents a subject of substantial interest, offering valuable insights in anthropological research as well as in clinical practice. The aim of this study is to document anatomical variants of the tarsal bones in a CISC//XXI skeletal sample (21st Century Identified Skeletal Collection), with a particular focus on the prevalence of accessory ossicles. Methods: The studied sample consisted of 163 individuals (83 females and 80 males). The prevalence of six accessory tarsal bones was recorded (os trigonum, calcaneum secundarium, the accessory navicular bone, os sustentaculum, os vesalianum and os intermetatarseum). Results: A total of 35 individuals (21.4%; 35/163) exhibited at least one accessory ossicle, with 13 females (15.7%; 13/83) and 22 males (27.5%; 22/80). The os trigonum and calcaneum secundarium were the most frequently observed accessory bones, respectively, in 9.3% (15/162) and 6.9% (11/159) of the individuals. No sex differences were observed. All accessory bones occurred more frequently unilaterally, and no co-occurrences of accessory bones were observed. Conclusions: These findings are crucial in both the biomedical and anthropological fields, where a detailed knowledge of foot anatomy and its variations is relevant. Full article

Background/Objectives: Magnetic resonance arthrography is the reference standard for evaluating glenoid labral lesions. Deep learning (DL) reconstruction algorithms may accelerate 3D acquisitions while maintaining image quality. This study assesses the diagnostic accuracy of DL-based isotropic 3D MR imaging for detecting glenoid labral lesions. Methods: This prospective study included 128 consecutive patients (79 men, 49 women; mean age 38.4 years) undergoing shoulder MR arthrography between June 2023 and April 2025. DL-based 3D sequences (acquisition time: 3:26) were compared with conventional multiplanar TSE and PD-FS sequences (acquisition time: 24–28 min). Two independent radiologists assessed glenoid labral lesions, bone marrow edema, and rotator cuff abnormalities using a four-point Likert scale. Sensitivity, specificity, and interobserver agreement were calculated. Results: DL-based 3D sequences demonstrated 94.7–95.1% sensitivity and 100% specificity for glenoid labral lesions, with excellent interobserver agreement (κ = 0.812). The area under the ROC curve was 0.894. Combined 3D protocols (T1 + PD-FS) showed superior accuracy (97.8%) compared to single sequences (90.5%, p = 0.012). For bone marrow edema, sensitivity was 82.9% with 100% specificity. Rotator cuff evaluation achieved 75% sensitivity with 100% specificity. Conclusions: DL-based isotropic 3D sequences provide high diagnostic accuracy for glenoid labral pathology while reducing scan time by 75%. Combined T1 and PD-FS protocols optimize performance. These findings support selective implementation of DL-accelerated 3D protocols in shoulder MR arthrography, particularly for labral assessment, while acknowledging that conventional protocols may remain preferable in specific clinical scenarios. Full article

Background: The present case report study aims to describe, from both clinical and histological aspects, the bone healing pattern in a patient under oral bisphosphonates therapy. Case Presentation: an 82-year-old female patient has been under oral nitrogen bisphosphonates therapy for two years. She underwent a tooth extraction. After four months, two bone biopsies were harvested, during standard implant drilling procedures. The first one corresponded to the healed alveolar socket of the previously extracted tooth (specimen A), while the second one corresponded to the bone ridge that was edentulous before starting the bisphosphonates therapy (specimen B). Morphometric and histologic analyses were performed. Results: In both, the bone resulted vital and no evidence of empty lacunae was detected. A reduction in the haversian canal diameter was observed in specimen B. The present case report highlights histological findings suggesting that patients undergoing oral bisphosphonates therapy may be eligible for surgical therapy. A pre-operative careful anamnesis and the observance of international guidelines for treating patients taking bisphosphonates are mandatory. Conclusions: These preliminary results will be used to plan a large clinical study in order to better understand the influence of bisphosphonates on the bone healing process. Full article

Bone remodeling is a dynamic process involving bone resorption and formation that is regulated on a cellular level and impacted by mechanical stress. A variety of Orthopedic surgery treatment strategies can affect bone remodeling, which can in turn may have long-term impacts on skeletal stress tolerance and function. This review provides a comprehensive overview of bone remodeling involved in Orthopedic surgery. Materials related to bone remodeling principles across Orthopedic surgery domains were selected and compiled using databases including PubMed, MEDLINE, AccessMedicine, and CINAHL; case studies were not included. Relevant literature was summarized for a general review of bone remodeling and as it relates to treatment principles in trauma, arthroplasty, and amputation with the aim of providing a relevant, comprehensive review. Overall, the purpose of this review is to provide an overview of bone remodeling principles that are implicated in various techniques within Orthopedic surgery. Full article

Background: Low peak bone mass (PBM) is a major contributor to later osteoporosis risk. This study sought to understand young people’s knowledge of factors associated with bone health. Methods: Young people in Aotearoa New Zealand were approached. Eight focus groups (26 participants in total, aged 11 to 17 years) were conducted using a semi-structured approach with open-ended questions and prompts. Transcripts were thematically coded using an inductive content analysis approach. Results: Knowledge of factors associated with good bone health was limited. There was a general awareness of the positive and negative impacts of many lifestyle behaviours on health generally, but not specifically PBM. Dairy intake was commonly mentioned as being beneficial for bone health. Some participants reported potential benefits of sport, but most did not know that weight bearing activity specifically was beneficial. Conclusions: Knowledge of osteoporosis and lifestyle factors that impact PBM was limited. Educational interventions involving promotion of bone health knowledge and supporting weight bearing physical activity in adolescents may be an important contributor to public health strategies. Full article