Protein Engineering: The Present and the Future
Conflicts of Interest
References
- Kesik-Brodacka, M. Progress in biopharmaceutical development. Biotechnol Appl Biochem. 2018, 65, 306–322. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Carlson, R.T. The Promise, Peril, and New Business of Engineering Life. In Biology Is Technology; Harvard University Press: Cambridge, MA, USA, 2011. [Google Scholar]
- Fersht, A.; Winter, G. Protein engineering. Trends Biochem Sci. 1992, 17, 292–295. [Google Scholar] [CrossRef]
- Marchenkov, V.; Ivashina, T.; Marchenko, N.; Ksenzenko, V.; Semisotnov, G. Bioluminescence Resonance Energy Transfer (BRET) Allows Monitoring the Barnase-Barstar Complex In Vivo. Biophysica 2022, 2, 72–78. [Google Scholar] [CrossRef]
- Arnold, F.H. Directed Evolution: Bringing New Chemistry to Life. Angew. Chem. Int. Ed. 2018, 57, 4143–4148. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Perkel, J.M. The computational protein designers. Nature 2019, 571, 585–587. [Google Scholar] [CrossRef] [Green Version]
- Deflandre, B.; Rigali, S. Old Enzyme, New Role: The β-Glucosidase BglC of Streptomyces scabiei Interferes with the Plant Defense Mechanism by Hydrolyzing Scopolin. Biophysica 2022, 2, 1–7. [Google Scholar] [CrossRef]
- Jumper, J.; Evans, R.; Pritzel, A.; Green, T.; Figurnov, M.; Ronneberger, O.; Hassabis, D. Highly accurate protein structure prediction with AlphaFold. Nature 2021, 596, 583–589. [Google Scholar] [CrossRef]
- Galano-Frutos, J.J.; García-Cebollada, H.; Sancho, J. Molecular dynamics simulations for genetic interpretation in protein coding regions: Where we are, where to go and when. Brief Bioinform. 2021, 22, 3–19. [Google Scholar] [CrossRef] [Green Version]
- Pucci, F.; Schwersensky, M.; Rooman, M. Artificial intelligence challenges for predicting the impact of mutations on protein stability. Curr. Opin. Struct Biol. 2022, 72, 161–168. [Google Scholar] [CrossRef] [PubMed]
- Chaudhary, N.; Weissman, D.; Whitehead, K.A. mRNA vaccines for infectious diseases: Principles, delivery and clinical translation. Nat. Rev. Drug. Discov. 2021, 20, 817–838. [Google Scholar] [CrossRef] [PubMed]
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Sancho, J. Protein Engineering: The Present and the Future. Biophysica 2022, 2, 111-112. https://doi.org/10.3390/biophysica2020011
Sancho J. Protein Engineering: The Present and the Future. Biophysica. 2022; 2(2):111-112. https://doi.org/10.3390/biophysica2020011
Chicago/Turabian StyleSancho, Javier. 2022. "Protein Engineering: The Present and the Future" Biophysica 2, no. 2: 111-112. https://doi.org/10.3390/biophysica2020011