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Radiation, Volume 5, Issue 4

2025 December - 13 articles

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Articles (13)

  • Article
  • Open Access
753 Views
22 Pages

Radionuclide-Dependent Stimulation of Antitumor Immunity in GD2-Targeted Radiopharmaceutical Therapy Combined with Immune Checkpoint Inhibitors

  • Cynthia Lilieholm,
  • Jen Zaborek,
  • Ohyun Kwon,
  • Adedamola O. Adeniyi,
  • Caroline P. Kerr,
  • Hansel Comas Rojas,
  • Malick Bio Idrissou,
  • Carolina A. Ferreira,
  • Paul A. Clark and
  • Jamey P. Weichert
  • + 10 authors

9 December 2025

Radiopharmaceutical therapy (RPT) offers tumor-selective radiation delivery and represents a promising platform for combination with immune checkpoint inhibitors (ICIs). While prior studies suggest that RPT can stimulate antitumor immunity, synergy w...

  • Article
  • Open Access
405 Views
10 Pages

Quality-of-Life Comparison of Three Different Breath-Hold Techniques for Left-Sided Breast Radiation

  • Caroline Hircock,
  • Adrian Wai Chan,
  • Anh Hoang,
  • Hanbo Chen,
  • Merrylee McGuffin,
  • Danny Vesprini,
  • Liying Zhang,
  • Matt Wronski and
  • Irene Karam

5 December 2025

Purpose: This study aimed to compare QoL outcomes among patients undergoing active breathing control (ABC), voluntary deep inspiration breath hold (vDIBH), and surface-guided radiation therapy (SGRT). Methods: This was a non-randomized, three-arm cli...

  • Article
  • Open Access
475 Views
12 Pages

4 December 2025

Introduction. This study aims to conduct a cost-effectiveness analysis comparing two primary treatment approaches: radical prostatectomy versus radiotherapy plus androgen deprivation therapy (ADT) in patients with Prostate Imaging Reporting and Data...

  • Case Report
  • Open Access
1 Citations
734 Views
9 Pages

Unilateral to Bilateral Lumbosacral Plexopathy After Radiation Therapy: A Case Report

  • Ezek Mathew,
  • Reyhan Meetheen,
  • Anand Shivnani and
  • Rob Dickerman

28 November 2025

Radiation therapy (RT) has been one of the standard treatments for prostate cancer; however, its potential impact on nearby neural structures, such as the lumbosacral plexus (LSP), is often overlooked. The lack of contouring in treatment plans has le...

  • Article
  • Open Access
623 Views
21 Pages

Whole Transcriptome Analysis of the Mouse Placenta Following Radiation-Induced Growth Restriction

  • Shayenthiran Sreetharan,
  • Sujeenthar Tharmalingam,
  • Cameron Hourtovenko,
  • Felix Tubin,
  • Christopher D. McTiernan,
  • Christopher Thome,
  • Neelam Khaper,
  • Douglas R. Boreham,
  • Simon J. Lees and
  • T.C. Tai

24 November 2025

High doses of ionizing radiation during prenatal development can cause growth restriction, or a decrease in growth of the developing offspring. This outcome of intrauterine growth restriction (IUGR) can predispose the offspring to lifelong health out...

  • Case Report
  • Open Access
826 Views
15 Pages

Online Adaptive Radiotherapy for Left-Sided Breast Cancer with Comprehensive Regional Nodal Coverage Including the Internal Mammary Chain: Case Report and Narrative Review

  • Damir Vučinić,
  • Matea Lekić,
  • Mihaela Mlinarić,
  • Giovanni Ursi,
  • Nikola Šegedin,
  • Vanda Leipold,
  • Domagoj Kosmina,
  • Hrvoje Kaučić,
  • Karla Schwarz and
  • Dragan Schwarz

20 November 2025

Online adaptive radiotherapy mitigates errors in absorbed dose delivery due to daily anatomical changes during hypofractionated breast treatment, particularly when comprehensive nodal therapy includes the internal mammary chain. To illustrate this, w...

  • Article
  • Open Access
995 Views
18 Pages

Establishing an Electron FLASH Platform for Preclinical Research in Low-Resource Settings

  • Banghao Zhou,
  • Lixiang Guo,
  • Weiguo Lu,
  • Mahbubur Rahman,
  • Rongxiao Zhang,
  • Varghese Anto Chirayath,
  • Yang Kyun Park,
  • Strahinja Stojadinovic,
  • Marvin Garza and
  • Ken Kang-Hsin Wang

11 November 2025

Background: FLASH radiotherapy delivers ultra-high dose rates with normal tissue sparing, but mechanisms remain unclear. We present a streamlined workflow for establishing a LINAC-based electron FLASH (eFLASH) platform in low-resource settings withou...

  • Article
  • Open Access
902 Views
42 Pages

3 November 2025

Fractal dimension (Frac) and lacunarity (Lac) are frequently proposed as biomarkers of multiscale image complexity, but their incremental value over standardized radiomics remains uncertain. We position both measures within the Image Biomarker Standa...

  • Review
  • Open Access
1,534 Views
15 Pages

16 October 2025

Prostatic artery embolization (PAE) is increasingly used as a primary minimally invasive treatment modality for lower urinary tract symptoms associated with benign prostatic hyperplasia. As a complex, fluoroscopic-guided endovascular procedure, PAE n...

  • Article
  • Open Access
784 Views
16 Pages

Microfluidic Isolation of Aptamers for Intracellular Measurement of Radio-Responsive Proteins

  • Xin Meng,
  • Leah Nemzow,
  • Yaru Han,
  • Kechun Wen,
  • Sally A. Amundson,
  • Helen C. Turner and
  • Qiao Lin

14 October 2025

In large-scale radiological events, there is a need to triage affected individuals based on their biological absorbed dose. Biodosimetry measures biological responses in relation to the received dose. Radiation-responsive protein biomarkers in periph...

  • Article
  • Open Access
1,264 Views
14 Pages

Impact of 6 MV-LINAC Radiation on Lymphocyte Phenotypes and Cytokine Profiles

  • Papichaya Yudech,
  • Wisawa Phongprapun,
  • Pittaya Dankulchai,
  • Duangporn Polpanich,
  • Abdelhamid Elaissari,
  • Rujira Wanotayan and
  • Kulachart Jangpatarapongsa

Radiotherapy employs high-energy X-rays to precisely target tumor tissues while minimizing damage to the surrounding healthy structures. Although its clinical efficacy is well established, the immunomodulatory effects of ionizing radiation remain com...

  • Article
  • Open Access
2,512 Views
15 Pages

Recalcitrant Pelvic Pain: Evaluating the Effectiveness of Radiofrequency Ablation for Pudendal, Genitofemoral, and Ilioinguinal Neuropathy

  • Zuhair Zaidi,
  • Sarah Attia,
  • Muaz Wahid,
  • Yin Xi,
  • Hareena Sangha,
  • Kelly Scott,
  • Rupali Kumar,
  • Flavio Duarte Silva and
  • Avneesh Chhabra

Chronic pelvic neuropathies involving the pudendal, ilioinguinal, and genitofemoral nerves are a major source of refractory pain and disability, yet conventional steroid injections typically provide only short-lived benefit. We retrospectively analyz...

  • Article
  • Open Access
1,505 Views
20 Pages

Comprehensive Dose–Response Analysis of the Effect of Ionizing Radiation on Hepatic Enzyme Parameters in a Rabbit Model

  • Aliyu Yakubu,
  • Ibrahim Abdulazeez Okene,
  • Chinedu Amaeze Frank,
  • Maruf Lawal,
  • Shamsaldeen Ibrahim Saeed and
  • Mohammed Dauda Goni

23 September 2025

Exposure to ionising radiation may be hazardous to living beings, including humans. Ionising radiation exposure has been shown to cause hepatic dysfunction or even liver cancer in persons receiving radiation therapy who do not have liver disease. Cha...

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Radiation - ISSN 2673-592X