Next Article in Journal
Vascular NADPH Oxidases and Atherothrombotic Stroke
Previous Article in Journal
Dynamics of Stress Biomarker in Cliff Divers during Official Competition
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Stresses
Volume 4
Issue 3
10.3390/stresses4030035
stresses-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Article

Enhanced Production of Therapeutic Metabolites in Cork-Oak Somatic Embryos under Abiotic Stress Conditions

by
Beatriz Pintos López
1,
José Antonio Manzanera
2,
Elena Pérez-Urria
1,
Carlos Jiménez
1,
Alba Montoro
1 and
Arancha Gomez-Garay
1,*
1
Research Group FiVe-A, Plant Physiology Unit, Faculty of Biology, Universidad Complutense de Madrid, Ciudad Universitaria, 28040 Madrid, Spain
2
Research Group FiVe-A, College of Forestry and Natural Environment, Universidad Politécnica de Madrid, Ciudad Universitaria, 28040 Madrid, Spain
*
Author to whom correspondence should be addressed.
Stresses 2024, 4(3), 546-557; https://doi.org/10.3390/stresses4030035
Submission received: 27 July 2024 / Revised: 28 August 2024 / Accepted: 29 August 2024 / Published: 3 September 2024
(This article belongs to the Section Plant and Photoautotrophic Stresses)
Browse Figures
Versions Notes

Abstract

This study investigates the enhanced production of key therapeutic metabolites (ellagic acid, serotonin, and chlorogenic acid) in response to abiotic stress in in vitro cultures of Quercus suber somatic embryos. Findings indicate significant increases in metabolite levels under various stress conditions, highlighting the potential for commercial-scale production of these compounds, known for their antioxidant, anticancer, and anti-COVID-19 properties. Under osmotic/saline stress, ellagic acid production significantly increased, representing an 80% increase compared to control conditions. In embryos exposed to different stressors, serotonin accumulation showed a six-fold increase under osmotic/saline stress. Although the elicitors used did not increase chlorogenic acid levels, exploring alternative stress types may enhance its production. This research paves the way for sustainable, large-scale production of health-beneficial metabolites, addressing global health challenges and promoting resource sustainability.
Keywords: somatic embryos; biofactory; chlorogenic acid; serotonin; ellagic acid; abiotic elicitation somatic embryos; biofactory; chlorogenic acid; serotonin; ellagic acid; abiotic elicitation

Share and Cite

MDPI and ACS Style

López, B.P.; Manzanera, J.A.; Pérez-Urria, E.; Jiménez, C.; Montoro, A.; Gomez-Garay, A. Enhanced Production of Therapeutic Metabolites in Cork-Oak Somatic Embryos under Abiotic Stress Conditions. Stresses 2024, 4, 546-557. https://doi.org/10.3390/stresses4030035

AMA Style

López BP, Manzanera JA, Pérez-Urria E, Jiménez C, Montoro A, Gomez-Garay A. Enhanced Production of Therapeutic Metabolites in Cork-Oak Somatic Embryos under Abiotic Stress Conditions. Stresses. 2024; 4(3):546-557. https://doi.org/10.3390/stresses4030035

Chicago/Turabian Style

López, Beatriz Pintos, José Antonio Manzanera, Elena Pérez-Urria, Carlos Jiménez, Alba Montoro, and Arancha Gomez-Garay. 2024. "Enhanced Production of Therapeutic Metabolites in Cork-Oak Somatic Embryos under Abiotic Stress Conditions" Stresses 4, no. 3: 546-557. https://doi.org/10.3390/stresses4030035

APA Style

López, B. P., Manzanera, J. A., Pérez-Urria, E., Jiménez, C., Montoro, A., & Gomez-Garay, A. (2024). Enhanced Production of Therapeutic Metabolites in Cork-Oak Somatic Embryos under Abiotic Stress Conditions. Stresses, 4(3), 546-557. https://doi.org/10.3390/stresses4030035

Article Metrics

Back to TopTop