COVID-19 Therapeutics Use by Social Deprivation Index in England, July 2020–April 2023

Round 1

Reviewer 1 Report

Comments and Suggestions for Authors

The manuscript provides an  analysis of COVID-19 therapeutic utilization in England, emphasizing disparities in treatment access among different demographic groups. The authors effectively underscore the significance of surveillance systems in monitoring therapeutic usage and addressing health disparities exacerbated by the pandemic, by setting and deprivation.

Overall, the manuscript contributes to our understanding of COVID-19 therapeutic utilization and its implications for health disparities in England. The research is well-presented, and the message is effectively conveyed. I have no further comments for the authors.

Author Response

Dear Reviewer, 

Thank you for reviewing our paper and for providing valuable feedback. Please find attached our revised manuscript.

Yours sincerely, 

Angela

Author Response File: Author Response.pdf

Reviewer 2 Report

Comments and Suggestions for Authors

Thank you for the opportunity to review this manuscript

some minor comments

Please align the manuscript to the RECORD-PE guidelines or other reporting guideline you consider appropriate

Please explain the IMD ranking system in the methods

Provide info on the setting to make it easier for the reader – some info on the health system is missing

Explain the coverage of database you used

Explain your main outcome measure, the variables used and the analysis in more detail

 

Make conclusion more specific to your findings

Author Response

Dear Reviewer, 

We would like to thank you for the opportunity to submit a revised copy of the manuscript above (covid-2942098). 

Following the reviews, we have carefully considered and addressed each comment. A summary of our response is outlined below, with corresponding changes highlighted in yellow in the revised manuscript.

Thank you again for your considering our revised manuscript.

Reviewer 2

Section	Comment	Response
Methods	1. Please align the manuscript to the RECORD-PE guidelines or other reporting guideline you consider appropriate.	Where applicable sections in methods adjusted to RECORD-PE guidelines
Methods	2. Please explain the IMD ranking system in the methods	Amended and explained in line 83-85
Methods	3. Provide info on the setting to make it easier for the reader – some info on the health system is missing	Added in line 85 to 90
Methods	4. Explain the coverage of database you used	Added in line 74 to 79
Methods	5. Explain your main outcome measure, the variables used and the analysis in more detail	Explained and added in line 92 to 93. Also, in line 97 to 99
Conclusion	6.Make conclusion more specific to your findings	Amended in line 217 to 218

 

Editorial Office

Section	Comment	Response
Institutional Review Board Statement	Please add	Added in line 235
Informed Consent Statement	Please add	Added in line 237

Yours sincerely, 

Angela Falola

Author Response File: Author Response.pdf