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Review

Oral Hygiene and Cardiovascular Health

by
Md S. Zaman
1,2,*,
S. M. Golam Alam
3 and
Mohammed S. Razzaque
4
1
Department of Biological Sciences, Alcorn State University, Lorman, MS 39096, USA
2
Department of Biology, South Texas College, McAllen, TX 78501, USA
3
Heart Institute, Doctors Hospital at Renaissance, Edinburg, TX 78539, USA
4
Department of Medical Education, University of Texas, Rio Grande Valley, Edinburg, TX 78539, USA
*
Author to whom correspondence should be addressed.
Hygiene 2025, 5(2), 14; https://doi.org/10.3390/hygiene5020014
Submission received: 27 December 2024 / Revised: 15 March 2025 / Accepted: 1 April 2025 / Published: 3 April 2025

Abstract

The human oral microbiome plays a vital role in maintaining oral and systemic health. This diverse microbial community includes over 700 bacterial species, some of which are implicated in developing systemic diseases, particularly cardiovascular diseases (CVDs). Research highlights a strong association between periodontal disease and increased cardiovascular risk, suggesting that good oral hygiene practices may reduce the incidence of CVDs. Porphyromonas gingivalis and Fusobacterium nucleatum drive chronic inflammation in periodontal disease; these bacteria can extend beyond the mouth and contribute to systemic inflammatory responses. The inflammatory factors, including C-reactive protein (CRP), interleukins (IL-1, IL-6), and tumor necrosis factor-alpha (TNF-α), damage blood vessels, impair endothelial functions, and promote atherosclerosis, all key events in CVD progression. Additionally, oral pathogens may accelerate plaque formation in arteries, increasing the risk of ischemic heart and brain diseases. Studies show a 28% increased risk of heart disease in individuals with periodontal disease. Treating periodontal disease can improve endothelial function and reduce inflammatory markers, emphasizing oral health management as a potential preventive strategy for CVD. Public health initiatives that emphasize oral hygiene and early periodontal disease treatment are crucial for broader cardiovascular care.
Keywords: oral microbiome; periodontal disease; systemic inflammation; cardiovascular disease; public health oral microbiome; periodontal disease; systemic inflammation; cardiovascular disease; public health

Share and Cite

MDPI and ACS Style

Zaman, M.S.; Alam, S.M.G.; Razzaque, M.S. Oral Hygiene and Cardiovascular Health. Hygiene 2025, 5, 14. https://doi.org/10.3390/hygiene5020014

AMA Style

Zaman MS, Alam SMG, Razzaque MS. Oral Hygiene and Cardiovascular Health. Hygiene. 2025; 5(2):14. https://doi.org/10.3390/hygiene5020014

Chicago/Turabian Style

Zaman, Md S., S. M. Golam Alam, and Mohammed S. Razzaque. 2025. "Oral Hygiene and Cardiovascular Health" Hygiene 5, no. 2: 14. https://doi.org/10.3390/hygiene5020014

APA Style

Zaman, M. S., Alam, S. M. G., & Razzaque, M. S. (2025). Oral Hygiene and Cardiovascular Health. Hygiene, 5(2), 14. https://doi.org/10.3390/hygiene5020014

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