The Use of Fish Oil Lipid Emulsion in the Treatment of Intestinal Failure Associated Liver Disease (IFALD)
Abstract
:1. Introduction
1.1. Essential Fatty Acids (EFAs)
1.2. Fatty Acid Regulation
1.3. Role of Fatty Acids in Inflammation
1.4. Intestinal Failure Associated Liver Disease (IFALD)
1.5. Lipid Emulsions and IFALD
Product | Intralipid | ClinOleic | SMOF lipid | Omegaven |
---|---|---|---|---|
Manufacturer | Baxter Healthcare/Fresenius Kabi | Baxter Healthcare/Parenteral SA | Fresenius Kabi | Fresenius Kabi |
Oil source (g) | ||||
Soy bean | 10 | 2 | 3 | 0 |
Safflower | 0 | 0 | 0 | 0 |
MCT | 0 | 0 | 3 | 0 |
Olive oil | 0 | 8 | 2.5 | 0 |
Fish oil | 0 | 0 | 1.5 | 10 |
Alpha Tocopherol | 38 | 32 | 200 | 150–296 |
Phytosterols (mg/L) | 348 ± 33 | 327 ± 8 | 47.6 | 0 |
Fat composition (g) | ||||
Linoleic | 5 | 0.9 | 1.87 | 0.1–0.7 |
Alpha-linolenic | 0.9 | 0.1 | 0.24 | <0.2 |
EPA | 0 | 0 | 0.24 | 1.28–2.82 |
DHA | 0 | 0 | 0.22 | 1.44–3.09 |
Oleic | 2.6 | 0.8 | 2.78 | 0.6–1.3 |
Palmitic | 1 | 0.7 | 0.92 | 0.25–1 |
Stearic | 0.35 | 0.2 | 0.27 | 0.05–0.2 |
Arachidonic | 0 | 0.03 | 0.05 | 0.1–0.4 |
1.6. Clinical Experience
1.7. Alternative IVLE Dosage Strategies
2. Conclusions
Conflict of Interest
References
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Chang, M.I.; Puder, M.; Gura, K.M. The Use of Fish Oil Lipid Emulsion in the Treatment of Intestinal Failure Associated Liver Disease (IFALD). Nutrients 2012, 4, 1828-1850. https://doi.org/10.3390/nu4121828
Chang MI, Puder M, Gura KM. The Use of Fish Oil Lipid Emulsion in the Treatment of Intestinal Failure Associated Liver Disease (IFALD). Nutrients. 2012; 4(12):1828-1850. https://doi.org/10.3390/nu4121828
Chicago/Turabian StyleChang, Melissa I., Mark Puder, and Kathleen M. Gura. 2012. "The Use of Fish Oil Lipid Emulsion in the Treatment of Intestinal Failure Associated Liver Disease (IFALD)" Nutrients 4, no. 12: 1828-1850. https://doi.org/10.3390/nu4121828
APA StyleChang, M. I., Puder, M., & Gura, K. M. (2012). The Use of Fish Oil Lipid Emulsion in the Treatment of Intestinal Failure Associated Liver Disease (IFALD). Nutrients, 4(12), 1828-1850. https://doi.org/10.3390/nu4121828