4th Free Webinar on Biomolecules: Recent advances on lysosomal storage disorders pathogenesis: an emerging Gaucher disease paradigm shift — 23rd October 2020
MDPI has provided several free open platforms that may help accelerate scientific exchange and support academics during this particularly difficult period. Thanks to our brilliant technical support, we are pleased to report that the fourth Free Webinar on Biomolecules: Recent advances on lysosomal storage disorders pathogenesis: an emerging Gaucher disease paradigm shift is coming soon.
Date & Time: 23 October 2020 03:00pm (CEST)
Duration: Maximum 2 hours
Webinar ID: 825 9187 3796
Register for Free Here: https://biomolecules-4.sciforum.net/
Chair: Dr. Enrico Moro
Department of Molecular Medicine, University of Padova, Padova, Italy.
Dr. Enrico Moro is an Associate Professor of Cell Biology at the Medical School of the University of Padova (Italy). He authored 60 full-length publications in peer-reviewed journals, including several high impact journals, such as Endocrine Reviews, Lancet, Developmental Cell, Cell Reports and PNAS. He was co-editor of two Special Issues of the Journal of Endocrinological Investigation, and he is currently Guest Editor of a Special Issue on Lysosomal Disorders in Biomolecules. His research publications present a total impact factor of 336 and a mean impact factor of 5.6; he has an h-index of 27. His research has been funded by different entities (Italian Ministry of Health 2010-2013, Genzyme-Sanofi 2012-2017 and MPS society 2019-2021). Dr. Moro has been invited as a speaker in several international and national meetings. He is also a member of the Scientific Advisory Board for the International Society for Mannosidosis & Related Diseases (ISMRD). He has a strong background in human cell biology, mouse and zebrafish manipulation, and his current research focuses on the study of lysosomal storage disorders, particularly Gaucher disease and Hunter Syndrome (Mucopolysaccharidosis type II).
Speakers: Dr. Ricardo A. Feldman, Dr. Andrea Dardis
Dr. Ricardo A. Feldman
Department of Microbiology and Immunology, University of Maryland School of Medicine (UMSOM), Baltimore, USA.
Dr. Ricardo A. Feldman is an Associate Professor at the University of Maryland School of Medicine (UMSOM). Dr. Feldman received his PhD from the Department of Cell Biology at New York University School of Medicine, working with Drs. Takashi Morimoto and David D. Sabatini. After that he was a post-doctoral fellow in Dr. Hidesaburo Hanafusa's laboratory at the Rockefeller University, where he identified several new tyrosine kinase oncogenes that had been captured by RNA tumor viruses, and their cellular homologs. Dr. Feldman then moved to the lab of Dr. Doug Lowy at the National Cancer Institute (NCI, USA). He then joined the faculty of the UMSOM Department of Microbiology and Immunology, where he currently studies the developmental and cellular abnormalities caused by GBA1 mutations in Gaucher disease and GBA1-associated Parkinson’s disease. Using patient-derived induced pluripotent stem cells (iPSC), his laboratory identified the Wnt/B-catenin and mTORC1 pathways as critical targets of the sphingolipid imbalance caused by GCase deficiency. Dr. Feldman is a founding member of The Center for Stem Cell Biology and Regenerative Medicine at UMSOM.
Dr. Andrea Dardis
Laboratory of the Regional Coordinator Centre for Rare Diseases, University Hospital of Udine, Italy.
Dr. Andrea Dardis is Head of the Laboratory of the Regional Coordinator Centre for Rare Diseases, Udine, Italy. She obtained her PhD in Molecular Biology from the University of Buenos Aires, Argentina and continued her training as a post-doctoral fellow at the Metabolic Unit, University of California, San Francisco, USA. During her training she was awarded Fellowship of the Lawson Wilkins Pediatric Endocrine Society. She then moved to Italy where she got a Specialist Degree in Medical Genetics at the University of Genoa. In 2003 she joined the Metabolic Diseases Unit, Pediatric Hospital “Burlo Garofolo”, Trieste, Italy, as a Research Scientist. In 2009 she moved to the Regional Coordinator centre for Rare Diseases in Udine, Italy, where she became Head of the laboratory. Dr. Dardis laboratory is mainly focused in the biochemical and molecular diagnosis of lysosomal storage diseases, the functional characterization of defective lysosomal enzymes and the study of molecular mechanisms involved in the pathogenesis of lysosomal storage disorders. Dr. Dardis is a board member of the European Working Group of Gaucher Disease and member of the board of trustees of the international Niemann Pick disease registry (INPDR).
Webinar Program
|
Presentation |
Time |
|
Dr. Enrico Moro "Blowin’ in the Wnt: how glucocerebrosidase may shape a cell differentiation program" |
03:00 pm (CEST) |
|
Q&A |
03:20 pm (CEST) |
|
Dr. Ricardo A. Feldman "GBA1 mutations cause neurodevelopmental defects and lysosomal dysfunction" |
03:30 pm (CEST) |
|
Q&A |
03:50 pm (CEST) |
|
Dr. Andrea Dardis "Cellular models for the study of the pathogenic cascade in Gaucher disease" |
04:00 pm (CEST) |
|
Q&A |
04:20 pm (CEST) |
|
Discussion and Concluding Remarks |
04:30 pm (CEST) |
For any questions about the webinar, please send an email to webinars@mdpi.com.