Since the outbreak of the SARS-CoV-2 infection in China at the end of 2019, more than 456 million confirmed cases of COVID-19, including more than 6 million deaths, have been reported to the World Health Organization (WHO). In addition to infection control and prevention intervention to contain COVID-19, scientists have worked hard to develop effective treatments against SARS-CoV-2, and many studies have investigated the clinical efficacy and safety of anti-COVID-19 treatment. However, the findings of these studies have not been consistent. Moreover, the emergence of SARS-CoV-2 variants has complicated the condition. We still urgently need updated evidence of the appropriate management of COVID-19.

We would like to take this opportunity to extend our appreciation to all the researchers who have contributed to the fight against this disease. In particular, we would like to highlight multiple research projects in this field, covering pathogenesis, clinical manifestation, early detection, new therapeutic strategies, and the pandemic's prevalence and incidence. The list of relevant papers can be seen below:

“A Focus on the Potential Antiviral Strategies in Early Phase Coronavirus Disease 2019 (Covid-19): A Narrative Review”
by Caterina Monari et al.
Life 2020, 10(8), 146; https://doi.org/10.3390/life10080146
Available online: https://www.mdpi.com/2075-1729/10/8/146

“Post-COVID-19 Condition: Where Are We Now?”
by Paula Boaventura et al.
Life 2022, 12(4), 517; https://doi.org/10.3390/life12040517
Available online: https://www.mdpi.com/2075-1729/12/4/517

“Long COVID in Children and Adolescents”
by Valentina Fainardi et al.
Life 2022, 12(2), 285; https://doi.org/10.3390/life12020285
Available online: https://www.mdpi.com/2075-1729/12/2/285

“Pulmonary Complications after COVID-19”
by Petr Jakubec et al.
Life 2022, 12(3), 357; https://doi.org/10.3390/life12030357
Available online: https://www.mdpi.com/2075-1729/12/3/357

“Robust Neutralizing Antibody Responses 6 Months Post Vaccination with BNT162b2: A Prospective Study in 308 Healthy Individuals”
by Evangelos Terpos et al.
Life 2021, 11(10), 1077; https://doi.org/10.3390/life11101077
Available online: https://www.mdpi.com/2075-1729/11/10/1077

“Evidence of Long-Lasting Humoral and Cellular Immunity against SARS-CoV-2 Even in Elderly COVID-19 Convalescents Showing a Mild to Moderate Disease Progression”
by Bastian Fischer et al.
Life 2021, 11(8), 805; https://doi.org/10.3390/life11080805
Available online: https://www.mdpi.com/2075-1729/11/8/805

“Depressive and Neurocognitive Disorders in the Context of the Inflammatory Background of COVID-19”
by Eliza Dąbrowska et al.
Life 2021, 11(10), 1056; https://doi.org/10.3390/life11101056
Available online: https://www.mdpi.com/2075-1729/11/10/1056

“The Effects of Persistent Olfactory and Gustatory Dysfunctions on Quality of Life in Long-COVID-19 Patients”
by Luigi Angelo Vaira et al.
Life 2022, 12(2), 141; https://doi.org/10.3390/life12020141
Available online: https://www.mdpi.com/2075-1729/12/2/141

“Changes in the Mean Medical Visits Due to Psychiatric Disease in Korean Children and Adolescents Before and During the COVID-19 Pandemic”
by So Young Kim et al.
Life 2022, 12(4), 600; https://doi.org/10.3390/life12040600
Available online: https://www.mdpi.com/2075-1729/12/4/600

“Self-Reported Long COVID in the General Population: Sociodemographic and Health Correlates in a Cross-National Sample”
by Tore Bonsaksen et al.
Life 2022, 12(6), 901; https://doi.org/10.3390/life12060901
Available online: https://www.mdpi.com/2075-1729/12/6/901