3D Cell Culture Systems: Current Technologies and Applications

A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Biomedical Engineering and Biomaterials".

Deadline for manuscript submissions: 30 June 2025 | Viewed by 117

Special Issue Editor


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Guest Editor
Department of Visceral, Transplant, Thoracic and Vascular Surgery, University of Leipzig Medical Center, 04103 Leipzig, Germany
Interests: 3D cell culture; tissue engineering; liver diseases; liver regenerative medicine; MSC; hepatocytes; toxicology; cell isolation; bioreactor culture

Special Issue Information

Dear Colleagues,

We are pleased to invite you to contribute to our Special Issue on "3D Cell Culture Systems: Current Technologies and Applications". The field of 3D cell culture systems has seen significant advancements in recent years, providing more physiologically relevant models compared to traditional 2D cultures. These systems are crucial for better understanding cell behavior, drug responses, and tissue engineering applications. The importance of this research area lies in its potential to revolutionize biomedical research and therapeutic development, offering more accurate models for studying diseases and testing new treatments.

This Special Issue aims to compile a comprehensive collection of papers that highlight the latest advancements, methodologies, and applications in the realm of 3D cell culture systems. By gathering contributions from leading researchers in the field, we seek to provide a platform for disseminating innovative technologies and novel applications that push the boundaries of current knowledge. Our goal is to establish a collection of at least 10 articles that will be of significant interest to scholars and practitioners. Should this number be reached, this Special Issue may be printed in book form, further broadening its impact.

In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following:

  • The development and optimization of 3D cell culture technologies;
  • Applications of 3D cell cultures in drug discovery and development;
  • Comparative studies between 2D and 3D cell culture systems;
  • Advances in biomaterials and scaffolds for 3D cultures;
  • The use of 3D cultures in cancer research, tissue engineering, and regenerative medicine;
  • High-throughput screening and imaging technologies for 3D cultures.

We look forward to receiving your contributions and working together to create a valuable resource that will benefit researchers, scholars, and practitioners alike.

Dr. Peggy Stock
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Bioengineering is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • 3D cell culture
  • tissue engineering
  • biomaterials
  • drug discovery
  • cancer research
  • regenerative medicine
  • scaffold technology
  • high-throughput screening
  • organoids
  • in vitro models

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Published Papers

This special issue is now open for submission.
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