Advances in mRNA-Based Nanomedicine
A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Nanotechnology Applications in Bioengineering".
Deadline for manuscript submissions: 31 August 2024 | Viewed by 149
Special Issue Editors
Interests: lipid nanoparticles; mRNA; vaccine; brain delivery; cell therapy
Special Issue Information
Dear Colleagues,
In vitro-transcribed (IVT) messenger RNA (mRNA) has emerged as a revolutionary therapeutic agent for preventing and treating various diseases. The mRNA molecules can generate rapid and precise expression of therapeutic proteins in the target cells and their extracellular microenvironment. Nevertheless, efficient and targeted delivery of mRNA molecules remains a significant challenge owing to their inherent instability and susceptibility to degradation. Advancements in nanoparticle delivery systems offer innovative solutions to surmount these obstacles and amplify the potency of mRNA therapeutics. Moreover, the rational design of mRNA sequences can enhance molecular stability, prolong the expression of desired proteins, and permit selective expression within targeted cells. Specifically, integrating advancements in nanoparticle technology with the latest understanding of mRNA structural biology will furnish a modular framework for designing next-generation mRNA-based nanomedicine.
This Special Issue, entitled ‘Advances in mRNA-Based Nanomedicine’, will focus on exploring the intersection of state-of-the-art material science and mRNA engineering to augment the therapeutic capabilities of mRNA technologies. We invite researchers to submit original research articles, communications, and review articles covering structural optimization of mRNA, innovation in nanomaterials, nanoparticle formulation fabrications, mRNA-based vaccines, tissue- or cell-specific delivery, manufacturing of mRNA therapies, mRNA-related immunogenicity, artificial intelligence-guided design, etc.
Dr. Yonger Xue
Dr. Zhiwei Fang
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Bioengineering is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- nanomaterials
- mRNA
- vaccines
- targeted delivery
- structural design
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