Advancements in Research on Metabolic Syndrome

A special issue of Cells (ISSN 2073-4409).

Deadline for manuscript submissions: 31 May 2026 | Viewed by 152

Special Issue Editor


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Guest Editor
Department of Genetics, University of North Carolina, Chapel Hill, NC, USA
Interests: genetics; genomics; diabetes; metabolic syndrome
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Special Issue Information

Dear Colleagues,

Metabolic syndrome is the leading risk factor for cardiovascular disease, type 2 diabetes and stroke. It is a multifaceted disorder that comprises abdominal obesity, hypertriglyceridemia, hyperglycemia, elevated blood pressure, and low levels of HDL cholesterol, and a person with at least three of these disorders can be considered metabolically obese. Metabolic syndrome is presently the leading cause of concern in the United States and worldwide. 

Various multi-omics approaches, such as proteomics and genomics, have been applied in biomedical research to identify the root cause of metabolic syndrome. Lifestyle-mediated lipid metabolism disorders, insulin resistance, and dysregulation of cytokines/adipokines are all implicated in fatty liver disease, which, along with genetics and environmental factors, plays a dominant role in development of metabolic syndrome. For this Special Issue, we welcome articles on transcriptomics, proteomics, lipidomics, and metabolomics that help identify the targets and pathways involved in the pathophysiology of metabolic diseases. Moreover, we welcome genomics studies, including genome-wide association studies (GWASs) and studies of GWAS candidate genes that can be used to identify polymorphisms and functional DNA variants associated directly with the occurrence of fatty liver or related metabolic traits.

Dr. Gautam Kumar Pandey
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • metabolic syndrome
  • multi-omics
  • insulin resistance
  • cell signaling in metabolic disease

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Published Papers

This special issue is now open for submission.
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