Extracellular Vesicles in Chronic Obstructive Pulmonary Disease: A 2025 Update
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: 15 April 2026 | Viewed by 15
Special Issue Editors
Interests: extracellular vesicles; mechanism underlying extracellular vesicle generation; intercellular communication; inflammatory markers; miRNAs; inflammation; coagulation; lung diseases
Special Issues, Collections and Topics in MDPI journals
Interests: extracellular vesicles; inflammatory markers; miRNAs; cell inflammation; lung diseases; alveolar macrophage polarization
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Chronic obstructive pulmonary disease (COPD) is a significant contributor to morbidity and mortality worldwide and is characterized by chronic inflammation, progressive airflow limitation, and diverse interactions between epithelial, immune, and structural lung cells. While EVs have increasingly been recognized in recent years for their essential role in intercellular communications, where they mediate the lung microenvironment, they are well-equipped to regulate immune responses, epithelial barrier integrity, and tissue remodeling.
This Special Issue will provide a window into the current view of the role of EVs in COPD. We welcome original research or review articles that focus on how EVs derived from structural or immune cells, or pathogens, are involved in the aetiology, exacerbations, and progression of COPD. Contributions discussing inflammation, cellular senescence, emphysematous changes, disease biomarkers, or targets for therapy, as well as smoking, environmental exposures, exacerbations, and the microbiota, are also welcome. This Special Issue aims to bring together mechanistic insights and translational perspectives to improve our understanding of EV biology in COPD and hopefully develop new avenues for the design of novel diagnostics and therapeutics.
Dr. Tommaso Neri
Dr. Erica Bazzan
Guest Editors
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Keywords
- extracellular vesicles (EVs)
- chronic obstructive pulmonary disease (COPD)
- inflammation
- epithelial barrier
- cellular senescence
- tissue remodeling
- biomarkers
- exacerbations
- microbiota
- therapeutic targets
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