Updates on the Mechanisms and Therapies of Cardiometabolic Disease
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cells of the Cardiovascular System".
Deadline for manuscript submissions: 31 December 2024 | Viewed by 146
Special Issue Editor
2. College of Professional Studies, Northeastern University, Boston, MA 02101-02117, USA
Interests: cell and gene therapy; cardiovascular disease; metabolic disease; atherosclerosis; dyslipidemia; animal models; drug discovery and development
Special Issue Information
Dear Colleagues,
Cardio-metabolic disorders that include cardiovascular and metabolic diseases such as diabetes are the leading cause of mortality globally. Almost 70% of patients with diabetes develop atherosclerotic cardiovascular disease (ASCVD). Metabolic pathway derangements lead to dyslipidemia and hyperglycemia and increase the risk of ASCVD by increasing glucose, oxidative stress and proatherogenic lipoproteins. Despite significant progress in targeting lipid and glucose metabolic pathways to develop new therapies for CVD treatment, reducing CVD risk in patients is still challenging. Therefore, examining novel pathways and using advanced technologies offer opportunities to understand cellular mechanisms and help develop CVD therapy.
This Special Issue focuses on the mechanism of metabolic pathways and in vitro/in vivo cellular functions to drive therapeutic approaches. New and novel cell and animal models and the use of antisense, mAbs, gene therapy and gene editing technologies now show potential to target novel pathways and tissues for CVD therapy.
Dr. Rai Ajit K. Srivastava
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- cardiovascular disease
- atherosclerosis
- metabolic disease
- hyperlipidemia
- diabetes
- proatherogenic lipoproteins
- drug discovery
- gene therapy/gene editing
- ASO
- mAb
