Updates of Stem Cell Applications in Bone Tissue Engineering
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Stem Cells".
Deadline for manuscript submissions: 20 March 2025 | Viewed by 118
Special Issue Editor
Interests: pluripotent stem cells; craniofacial biology; neural crest development; osteogenic cells; keratinocytes; stem cell biology; reprogramming; stem cell differentiation; tissue engineering
Special Issue Information
Dear Colleagues，
Having healthy and functional bones is crucial for sustaining a high quality of life. Bone defects, a common orthopedic issue, can cause prolonged patient morbidity. Thus, bone tissue engineering holds significant therapeutic potential.
Bone tissue engineering is a cutting-edge approach in regenerative medicine and dentistry that utilizes scaffolds, integrated cells, and bioactive growth factors to promote the healing and regrowth of bones. Stem cells, such as induced pluripotent stem cells (iPSCs), bone marrow-derived mesenchymal stem cells (BM-MSCs), umbilical cord blood-derived mesenchymal stem cells (UCB-MSCs), adipose tissue-derived stem cells (ADSCs), muscle-derived stem cells (MDSCs), and dental pulp stem cells (DPSCs), have recently gained considerable interest. This is because they possess unique biological abilities to transform into osteogenic progenitor cells in vitro. These progenitor cells have the capacity to generate bone and repair bone defects in vivo. Hence, it is crucial to develop efficient and sophisticated strategies to effectively guide the differentiation of stem cells towards the osteogenic lineage in vitro and thoroughly analyze their characteristics in vivo. This could reduce the potential of spontaneous differentiation into non osteogenic lineages and enhance the abundance of specialized osteogenic progenitor populations for potential application in tissue engineering therapies.
We invite you to submit original research and review articles investigating various aspects of utilizing different types of stem cells in studies relevant to bone tissue engineering.
Dr. Fahad Karim Kidwai
Guest Editor
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Keywords
- stem cells
- bone tissue engineering
- bone diseases
- bone repair
- bone defect
- bone healing
- bone regeneration
- osteogenic progenitor cells
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