Research on T Cells in Skin Inflammatory Disorders
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Immunology".
Deadline for manuscript submissions: 28 February 2025 | Viewed by 65
Special Issue Editors
2. Dermatology Section, Department of Medicine, VA San Diego Health System, San Diego, CA, USA
Interests: T cell malignancies; lymphoma; epigenetic; biomarker; immune microenvironment; DNA methylation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The skin is a complex organ that provides critical roles in immune surveillance. T cells are critical cells that contribute to the tissue microenvironment in the regulation of an effective immune response. Recent research has led to illuminating the heterogenous nature of T cell populations, with the identification of novel T cell subsets defined by cytokine expression that contributes to unique function in immunoregulation. The well-orchestrated reaction of a normal immune response can at times deviate along an abnormal path, with dysregulation of T cells’ function, leading to a number of heterogenous inflammatory and neoplastic T cell proliferative diseases. The spectrum of abnormality in T cells in the skin is diverse. Dissecting normal T cell function and how these regulatory pathways run amok is important to understanding the pathogenesis of skin disease. The advances have shed insight into the role of T cells in immune skin diseases such as atopic dermatitis, psoriasis, vitiligo, hidradenitis suppurative, connective tissue skin disease, as well as malignancies of T cells. Confirming the critical participation of T cells in skin disease has enabled the development of novel drugs that can affect T cell function with a dramatic impact on disease and improvement in patients quality of life. For this Special Issue, we invite authors to submit original articles or reviews that discuss insights into the role of T cells in normal immunity as well as in skin diseases, and therapeutics targeting T cells.
Dr. Henry K. Wong
Dr. Qing-Sheng Mi
Guest Editors
Manuscript Submission Information
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Keywords
- T cell
- vitiligo
- atopic dermatitis
- T cell lymphoma
