Novel Insights into Bone and Cartilage Biology: Bone Marrow-Derived Stromal Cells

A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Stem Cells".

Deadline for manuscript submissions: closed (10 January 2024) | Viewed by 125

Special Issue Editors


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Guest Editor
Biologics Engineering, Oncology R&D, AstraZeneca, Gaithersburg, MD 20878, USA
Interests: stem cells; cell therapy; cancer; bone marrow; bone marrow stromal cells; cartilage tissue engineering
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
National Institute of Dental and Craniofacial Research (NIDCR), National Institutes of Health (NIH), Department of Health and Human Services, Bethesda, MD 20892, USA
Interests: synovial joint development; cartilage; skeletal repair; bone marrow stromal cells; gene engineering

Special Issue Information

Dear Colleagues,

With the advancement of medicine and technology, humans are living longer, and healthy ageing has become a significant medical and economic priority. Articular cartilage defects, as well as general wear and tear associated with ageing, lead to high frequencies of osteoarthritis in ageing populations.  Osteoarthritis is a leading cause of pain and immobility in the Western world and is the leading cause of early retirement.  Similarly, skeletal challenges such as non-union of bone fractures and osteoporosis increase in prevalence in ageing populations.  The focus of this Special Issue is on bone marrow-derived stromal cells (BMSC) and the application of these cells to cartilage and bone repair. BMSC have been shown to have chondrogenic and osteogenic differentiation potential, making them a potential precursor cell for cartilage or bone tissue engineering.  In this Special Issue we hope to capture original research or expert perspective reviews of the literature related to BMSC biology, the developmental processes that guide bone and cartilage tissue formation, as well as therapeutic strategies that use BMSC as cell therapies to facilitate bone or cartilage tissue repair. 

We look forward to receiving your articles and to working with you to establish a meaningful collection of publications on these important topics.

Dr. Michael Robert Doran
Dr. Kathryn Futrega
Guest Editors

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Keywords

  • bone marrow-derived stromal cell
  • cartilage
  • bone
  • skeletal development
  • regeneration

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Published Papers

There is no accepted submissions to this special issue at this moment.
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