Molecular and Cellular Mechanisms of Central Nervous System Autoimmunity
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cells of the Nervous System".
Deadline for manuscript submissions: 20 December 2024 | Viewed by 163
Special Issue Editors
Interests: neuroimmunology; multiple sclerosis (clinical/experimental); animal models; glial cells; biomarkers in MS; neuroprotection; neuroimaging
Special Issues, Collections and Topics in MDPI journals
Interests: neuroimmunology; multiple sclerosis (clinical/experimental); stroke (clinical/experimental); thromboinflammation; neuroprotection; neuroimaging
Special Issues, Collections and Topics in MDPI journals
Interests: neuroimmunology; multiple sclerosis (clinical/experimental); animal models; glial cells; immune tolerance
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue aims to explore the complex relationships and interactions between the central nervous system (CNS) and immune system based on maintaining immune balance in our bodies and developing and responding to autoimmune diseases that affect these vital systems. The immune system has evolved several mechanisms to control self-reactivity, and disruptions in one or more of these mechanisms can lead to a breakdown of immune tolerance. Autoreactivity ranges from a physiological level of self-reactivity to immune-mediated organ damage. Immune-mediated CNS attacks are predominantly triggered by cell-mediated mechanisms or autoantibodies directed against neural or glial target antigens.
This dynamic interdisciplinary field represents a rapidly expanding area of translational research that could potentially improve diagnosis, prognosis, and treatment outcomes. New antibodies or targets have continued to be described in antibody-mediated CNS autoimmunity, such as antibodies specific to oligodendrocyte myelin glycoprotein. Some previously seronegative or tumefactive disease manifestations can be assigned to this new entity.
With a focus on experimental cellular biology, we welcome the submission of original research and review articles addressing the molecular and cellular events implicated in the breakdown of CNS immune tolerance; the exacerbation of inflammation, demyelination, and neurodegeneration; novel aspects of current therapeutic interventions for CNS autoimmune diseases; and the discovery of advanced strategies to prevent or treat these complex disorders.
Prof. Dr. Refik Pul
Prof. Dr. Christoph Kleinschnitz
Dr. Jelena Skuljec
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- neuroimmunity
- central nervous system
- autoimmunity
- immune tolerance
- multiple sclerosis
- antibody-mediated autoimmunity
- cellular immunology
- neuroinflammation
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.
