Impact of Platelet Defects on Pathophysiological Processes II
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Pathology".
Deadline for manuscript submissions: 31 January 2025 | Viewed by 179
Special Issue Editors
Interests: inherited platelet defects; platelet physiology; septins
Special Issues, Collections and Topics in MDPI journals
Interests: coagulation; platelets; haemostasis; omics; signal transduction; thrombo-inflammation; thrombosis; vessel wall
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Platelets play a major cellular role in the regulation of coagulation and thrombosis. Platelets are non-nucleated ligations from megakaryocytes that exhibit multiple interactions with the vascular endothelium and provide a procoagulant surface that is crucial to clot formation. Additionally, platelets have been shown to act as mediators of immunity and inflammation, either by direct interaction with immune cells or by the granule release of proinflammatory/immunomodulating molecules. Consequently, platelet dysfunction, be it hereditary, acquired, or pharmacologically induced, contributes to various pathological processes, such as bleeding, thrombosis, acute/chronic inflammation, metastasis, and bacterial infection.
This Special Issue aims to promote research investigating how platelets are involved in various pathophysiological processes, and how specific platelet defects contribute to the development and progression of disease. Therefore, we welcome basic research on cellular/molecular interactions.
As the Guest Editors for this Special Issue, I call on all researchers in this evolving field to contribute articles and help to make this Special Issue a valuable contribution to understanding platelet function.
Dr. Barbara Zieger
Dr. Kerstin Jurk
Guest Editors
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Keywords
- platelet physiology
- platelet pathophysiology
- inherited platelet defects
- signaling
- bleeding
- sepsis
- acquired platelet disorder
- developmental pathogenesis
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Related Special Issue
- Impact of Platelet Defects on Pathophysiological Processes in Cells (8 articles)
