Intracellular Mechanism in Differentiation, Proliferation and Cell Death
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Pathology".
Deadline for manuscript submissions: 1 November 2024 | Viewed by 380
Special Issue Editors
Interests: mesenchymal stem cells; regenerative medicine; epigenetics; immunotoxicology; immunomodulation; inflammation
Special Issues, Collections and Topics in MDPI journals
Interests: regenerative medicine; mesenchymal stem cells; differentiation factors; signaling pathway; nitric oxide; far-infrared radiation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cells have their own unique as well as pleiotropic roles to perform in numerous biological activities to assist in maintaining biological homeostasis. All these processes are achieved through the complex internal and external interaction of molecular signals. The internal maneuvers are crucial for the cells to adapt in response to external cues and, as a consequence, understanding these underlying intracellular mechanisms is important for studying cells. General cellular processes, including proliferation, differentiation and cell death (apoptosis versus necrosis), are the most commonly assessed endpoints in evaluating the medicinal or toxic effects of chemical, biological and any other external factors. Many studies have been performed in relation to these biological processes, yet their underlying mechanisms have not yet been fully understood due to the complexity of the regulatory mechanisms involved. There are still many intracellular mechanisms to discover in the diverse field of cell biology such as immunology, neurology, toxicology, regenerative medicine and so on. For example, stem cells are capable of self-renewal until undergoing an epigenomic arrangement or differentiation to become functional adult cells. However, it is still difficult to control their proliferation and differentiation due to uncertainty in their intracellular regulatory mechanisms, making their application difficult in clinical field.
This special issue aims to extend knowledge on the complex intracellular regulatory mechanisms of differentiation, proliferation and cell death in the hope of forging safe and effective treatments for various pathological conditions.
Dr. Steve (Se-Young) Oh
Prof. Dr. Inho Jo
Guest Editors
Manuscript Submission Information
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Keywords
- intracellular mechanism
- molecular pathway
- differentiation
- proliferation
- cell death
- apoptosis
- necrosis
- inflammation
- epigenomics
- proteomics
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