The Diverse Roles of DNA Methylation and Hydroxymethylation in Embryonic Development
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: 31 January 2025 | Viewed by 162
Special Issue Editor
Interests: prenatal exposures; environmental chemicals; environmental toxicants; humans and model organisms; health outcomes in offspring
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
It is my pleasure to invite you to submit your articles or reviews to a Special Issue of Cells titled, ‘The Diverse Roles of DNA Methylation and Hydroxymethylation in Embryonic Development’. After fertilization of an egg by a sperm, the DNA in the embryo undergoes multiple rounds of DNA methylation, as well as both active and passive DNA demethylation. Active DNA demethylation by the TET family of enzymes is needed to generate a naïve state for the embryo to create pluripotent stem cells for both the embryonic and extraembryonic lineages. De novo DNA methylation by the Dnmt3a,3b enzymes is needed to generate the multiple lineages derived from both embryonic stem cells and trophoblast stem cells. This Special Issue will cover research on DNA methylation and DNA hydroxymethylation changes in embryonic cells from fertilization to birth in mammalian development.
Prof. Dr. Douglas M. Ruden
Guest Editor
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- DNA methylation
- DNA hydroxymethylation
- mouse embryonic development
- human embryonic development
- Tet
- Dnmt
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