Electrochemical Sensors for Biomedical Analysis

Dear Colleagues,

Electrochemical sensors and biosensors have gained popularity in recent years, which is linked to the progress of materials, the increasingly refined use of biological components, and their application in analytical methods. The fields of application are diverse, from the study of production processes to food quality, but it is above all the application of electrochemical sensors to the field of human health (in both preventive and diagnostic–therapeutic functions) that promises a real revolution in the coming years. Diagnostic systems integrated in distributed sensor networks find in electrochemical sensors the ideal elements for advanced 'bedside' diagnostics that do not require complex analytical equipment and dedicated laboratories. This is the prediction for the future for advanced societies, but also for developing nations that lack state-of-the-art healthcare services. Territorial medicine and telemedicine will increasingly rely on small, low-cost, easily transportable, and interfaceable precision analytical devices: electrochemical sensors and biosensors are the ideal devices for these applications. Diagnosing infectious diseases or neoplasms, quantifying metabolites, antigens, or antibodies, and validating the presence of specific DNA or RNA sequences are just some of the applications of electrochemical (bio)sensors that have the potential to revolutionise large-scale diagnostics. Designing, characterising, and validating an electrochemical (bio)sensor with relevant and predictable analytical performance is not always easy, and the time-to-market is often very long. Indeed, biological fluids are complex matrices, and sample preparation requires equipment that is not always present in the places where the sensors are used. For a 'real-world' application, i.e., those outside the laboratory, sensors must be able to work on samples that are minimally treated or not treated at all. This Special Issue of Chemosensors brings together original studies or systematic literature reviews representing the state of the art of electrochemical sensors applied to biomedical analysis.

The scope of Chemosensors spans topics concerning the development, characterisation, and application of chemical sensors. Electrochemical sensors and biosensors represent a subset of chemical sensors. The application of electrochemical sensors for the prevention, diagnosis, and treatment of diseases is a field that has undergone extensive development in recent years.

The topics of interest for this Special Issue are as follows:

• Development and characterisation of electrochemical sensors and biosensors for the detection of molecules of biomedical interest;
• Application and study of new transducers and/or polymers for electrochemical sensing of molecules of biomedical interest;
• Nanostructuring of transducers for increasing the performance of electrochemical sensors applied to the study of molecules of biomedical interest;
• Development/application of electrochemical methods for the analysis of molecules of biomedical interest;
• Sensors and biosensors for DNA and RNA analysis;
• Sensors and biosensors for the analysis of small molecules, peptides, and proteins;
• Immunobiosensors;
• Interfering signal reduction strategies (biological matrix adaptation);
• Innovative biological sample pre-processing for reducing electrochemical interferents;
• Application of electrochemical sensors/biosensors to study analytes in biological fluids;
• Strategies aimed at increasing the shelf-life of sensors and their application in difficult contexts far from the laboratory (bedside);
• Development of electrochemical systems for studying multiple analytes from the same biological sample;
• Development of integrated and/or portable electronic systems to interface with electrochemical sensors for biomedical analysis;
• Development/integration of electrochemical sensor networks for biomedical and telemedicine applications;
• Systematic literature review on topics related to current developments/trends in electrochemical sensor technology applied to human health.

Prof. Dr. Pier Andrea Serra
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Chemosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• electrochemical (immuno)(bio)sensors
• biological fluids
• health applications
• electrochemical interferences
• biological sample preparation
• telemedicine
• bedside
• sensor networks
• bioeletronics