Luminescent Metal Complexes as Sensors
A special issue of Chemosensors (ISSN 2227-9040). This special issue belongs to the section "Optical Chemical Sensors".
Deadline for manuscript submissions: closed (28 February 2021) | Viewed by 6472
Special Issue Editors
Interests: molecular imaging; chemical biology; bio-inorganic chemistry; medicinal chemistry
Interests: Inorganic Chemistry, Organic Synthesis, Photodynamic Therapy, Cancer Drug Delivery, Fluorescent Sensors, Cellular Imaging
Interests: Organic Synthesis, Fluorescent dyes (and their applications), Small-Molecule Sensors, Photophysics and Photochemistry, Nanoscopy
Special Issue Information
Dear colleagues,
Luminescent metal complexes display intriguing photophysical and photochemical properties and are garnering interest as versatile tools in the multidisciplinary field of chemistry and chemical biology. The desirable luminescent features of metal complexes such as long-lived emission, high photostability, large Stokes shifts, and sensitivity to the surrounding microenvironment render them well-suited for use in labeling, imaging, or sensing of small bio-analytes, as well as biomacromolecules such as proteins, enzymes, and oligonucleotides. The utility of metal complexes as luminescent probes can provide fundamental insight into mechanistic features of cellular events or function as diagnostic agents in biomedical applications. Additionally, luminescent probes for specific biocatalytic transformations are important bioanalytical tools for the detection and quantification of enzymatic activity. Elevated or reduced levels of specific enzyme activity often serve as biomarkers of human disease. Additionally, such metal complexes often possess desirable intrinsic therapeutic properties (e.g., anticancer, antibacterial, and antihelminthic activities), therefore creating opportunities for the potential development of novel theranostic agents.
The objective of this Special Issue is to provide a forum to present and collate significant research involving the application of luminescent inorganic and organometallic metal complexes as probes in molecular imaging. In addition, research related to bioactive luminescent metal complexes for dual monitoring and therapy of human diseases will be included.
Potential topics include but are not limited to the following:
- Development of luminescent metal complexes for DNA and RNA structures;
- Design of metal complexes with emission in the near-infrared (NIR) region;
- Luminescent metal complexes with applications in diagnosis of neurodegenerative diseases such as imaging of amyloid and tau proteins;
- Tuning luminescent properties of metal complexes for imaging applications;
- Bioactive luminescent metal complexes for biomedical applications;
- Membrane permeable luminescent metal complexes for imaging applications;
- Live cell imaging using phosphorescent metal complexes;
- Design of metal complexes as sensors for biomacromolecules;
- Theranostics based on metal complexes for cancer therapy;
- Development of metal complexes as sensors of anions and cations;
- Metal-organic frameworks as biosensors;
- Luminescent metal complexes with aggregation-induced emission (AIE);
- Phosphorescent metal complexes as biosensors for enzymatic activity;
- Design of luminescent metal complexes for applications in photodynamic therapy.
Dr. Koushambi Mitra
Dr. Jonas Bucevicius
Guest Editors
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