Dedicated to Professor Huangxian Ju and Professor Xueji Zhang on the Occasion of Their 60th Birthday for Their Outstanding Contributions to the Field of Chemical/Bio Sensors

A special issue of Chemosensors (ISSN 2227-9040). This special issue belongs to the section "(Bio)chemical Sensing".

Deadline for manuscript submissions: 31 December 2024 | Viewed by 889

Special Issue Editors


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Guest Editor
1. Jiangsu Collaborative Innovation Center of Biomedical Functional Materials, Jiangsu Key Laboratory of Biofunctional Materials, School of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210023, China
2. School of Chemistry and Molecular Engineering, Nanjing Tech University, Nanjing 211816, China
Interests: bioelectroanalytical chemistry; biosensors

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State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Chemistry and Biomedicine Innovation Center, Nanjing University, Nanjing 210023, China
Interests: cell surface glycan sensing; glycan editing; in vivo glycan imaging; proximity labeling

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Guest Editor
School of Biomedical Engineering, Health Science Centre, Shenzhen University, Shenzhen 518060, China
Interests: nucleic acid biosensors; nano-medicines; theranostics nanosystems; nanoprobes

Special Issue Information

Dear Colleagues,

This Special Issue is dedicated to Professor Huangxian Ju and Professor Xueji Zhang on the occasion of their 60th birthday and the 20th anniversary of their acquaintance at the 1st I3S (International symposium on sensors science) conference, as recognition of their significant contributions to the field.

Huangxian Ju, born on Nov. 10, 1964, is currently a professor in Nanjing University, the director of State Key Laboratory of Analytical Chemistry for Life Science. He is one of the pioneers in nanobiosensing, ECL biosensing based on inorganic nanoparticles, the in situ analysis of cell surface carbohydrates, and real-time therapeutic monitoring. He was elected a fellow of the International Society of Electrochemistry and the Royal Society of Chemistry in 2015, Fellows of the International Society of Electrochemistry and the Royal Society of Chemistry in 2015, and a Fellow of the Chinese Society of Chemistry in 2023. He won the 2022 Advances in Measurement Science Lectureship Awards. He serves as the chief editor of Targets and Frontiers in Chemistry: Analytical Chemistry, an associate editor of Sensors and Journal of Analysis and Testing, and has been an editorial member of more than 20 international journals. The research interests of Professor Huangxian Ju include analytical biochemistry, nanobiosensing, bioimaging, and molecular diagnosis. He has published 932 papers (871 papers in SCI journals), and has authored 96 patents (48 approved), 6 English books, 7 Chinese books, 20 chapters for 10 Chinese and 10 English books, and 8 editorial, preface, or book reviews. Up to June 30 2024, his research works have more than 47000 citations in SCI journals (>45000 by other authors) with an h-index of 107 (Google Scholar h-index 119 with more than 54000 citations).

Xueji Zhang, born in February 1964, is the Vice President of Shenzhen University and Distinguish Professor in the School of Biomedical Engineering at the Shenzhen University. He was a research scientist, Sr. scientist, chief scientist, Vice President, and Sr. Vice President at World Precision Instruments, Inc. USA from 1999 to 2012 before he joined USTB as National Chair Professor. His research interests span the disciplines of chemistry, biology, materials, and medicine, with an emphasis on studies of wearable sensor, intelligent sensors,biosensing, biomedicine, and biomaterials. His lab focuses on the development of novel biosensors, tools, and devices to study free radicals, cancer biomarkers, profiling changes in animal or human associated with diseases, and exploiting this information for the development of diagnostic and therapeutic approaches. In addition, his group investigates drug delivery, new energy, and natural medicines. He serves as the chief editor of the RSC journal Sensors & Diagnostics and has been editorial member of 24 international journals. He has received numerous national and international awards and honors including Member European Academy of Sciences, Member of Russian Academy of Engineering, Fellow of American Institute for Medical and Bioengineering, Fellow of Royal Chemical Society, National Innovation Award, China, Scientist of Year in China, and Simon Fellow of ICSC-World Lab. He has authored over 700 papers, 8 books, and over 200 patents (with 40000 citations and H= 107), and has developed numerous sensors and instruments for commercialization.

Since Prof. Ju met Prof Zhang at the 1st I3S in Paris in 2003; they have carried out extensive and in-depth scientific research cooperation, which led to 16 articles published in many international journals, as well as the 3 following books: Electrochemical Sensors, Biosensors and Their Biomedical Applications, Academic Press (2007) and Chemical Industry Press in Chinese (2009); NanoBiosensing—Principles, Development and Application, Springer (2011) and Science Press in in Chinese (2009); Nucleic Acid Detection: Methods for analysis of DNA and microRNA, Intellectual Property Press in Chinese (2015).

The purpose of this Special Issue is to pay tribute to the significant contributions to these fields of Professor Huangxian Ju and Professor Xueji Zhang. We cordially and earnestly invite researchers to contribute your original and high-quality papers that will inspire advances in chemical sensors and biosensors.

Prof. Dr. Zhihui Dai
Prof. Dr. Lin Ding
Prof. Dr. Haifeng Dong
Guest Editors

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Keywords

  • chemical sensors
  • biosensors and bioimaging
  • nanosensors
  • wearable sensors
  • molecular diagnosis
  • life analytical chemistry

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Published Papers (1 paper)

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Research

11 pages, 2313 KiB  
Article
Water-Soluble Photoluminescent Ag Nanoclusters Stabilized by Amphiphilic Copolymers as Nanoprobe for Hypochlorite Detection
by Xiangfang Lin, Qinhui Dong, Yalin Chang, Shusheng Zhang and Pengfei Shi
Chemosensors 2024, 12(8), 166; https://doi.org/10.3390/chemosensors12080166 - 17 Aug 2024
Viewed by 536
Abstract
Luminescent Ag nanoclusters (Ag NCs) are a promising probe material for sensing and bioimaging applications. However, the intrinsic obstacle of poor water stability and photostability greatly restrict their practical application in biological systems. Herein, we report the intracellular hypochlorite (ClO) detection [...] Read more.
Luminescent Ag nanoclusters (Ag NCs) are a promising probe material for sensing and bioimaging applications. However, the intrinsic obstacle of poor water stability and photostability greatly restrict their practical application in biological systems. Herein, we report the intracellular hypochlorite (ClO) detection with amphiphilic copolymer-modified luminescent Ag NCs with good biocompatibility and photostability. The Ag NCs were synthesized by using chemically inert hydrophobic ligands and then modified with an amphiphilic (1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(poly(ethylene glycol))-2000]) (DSPE-PEG-2000) and sodium dodecyl sulfonate (SDS) for phase transfer. It was found that the approach of the removal of organic solvents during the phase transfer has remarkable influences on the properties of the Ag NCs, including their size, luminescence property, and aqueous stability. Furthermore, the silver core of Ag NCs could be oxidatively damaged by ClO, thereby causing photoluminescence (PL) quenching. The ClO-induced PL quenching was specific over the other common reactive oxygen species (ROS) as well as some common interferences. Finally, they have been successfully applied as a fluorescent nanoprobe for detecting exogenous and endogenous ClO in living cells. Full article
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