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Children
Special Issues
Management of Hydrocephalus in Children
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Management of Hydrocephalus in Children

A special issue of Children (ISSN 2227-9067). This special issue belongs to the section "Pediatric Neurology & Neurodevelopmental Disorders".

Deadline for manuscript submissions: closed (15 November 2022) | Viewed by 2761

Special Issue Editors

Dr. Leandro Castaneyra-Ruiz

E-Mail Website
Guest Editor
CHOC Childrens Res Inst, 1201 W La Veta Ave, Orange, CA 92868, USA
Interests: hydrocephalus
Prof. Dr. Agustín Castañeyra-Perdomo

E-Mail Website
Guest Editor
Facultad de Ciencias de la Salud, San Cristobal de La Laguna, Spain
Interests: hydrocephalus; neuropathology; neurodegeneration; cerebrospinal fluid

Special Issue Information

Dear Colleagues,

Hydrocephalus is a multifactorial neurological disorder that affects approximately 1 in 1100 children worldwide. Its primary treatment is a surgical diversion of CSF, representing the most common surgery for pediatric neurosurgeons. However, this treatment fails at an unacceptably high rate. Currently, the mechanisms underlying the etiology of pediatric hydrocephalus and the nature of its treatment failure are not well known. Thus, hydrocephalus management remains one of the main challenges for neurosurgeons. 

We invite you to contribute to this Special Issue to build on the knowledge of pediatric hydrocephalus regarding etiology, diagnosis, and treatment in basic and clinical science to improve the management of this disease and, therefore, children's health care. Both reviews and original research will be considered for publication.

Dr. Leandro Castaneyra-Ruiz
Prof. Dr. Agustín Castañeyra-Perdomo
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Children is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • hydrocephalus etiology
  • VZ disruption
  • reactive astrogliosis
  • inflammation
  • choroid plexus
  • circumventricular organs
  • cerebrospinal fluid
  • shunt failure
  • intracranial pressure
  • flow/pressure performance

Published Papers (1 paper)

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Research

7 pages, 364 KiB  
Article
Sensitivity of Papilledema as a Sign of Increased Intracranial Pressure
by David Krahulik, Lumir Hrabalek, Filip Blazek, Matej Halaj, Marek Slachta, Eva Klaskova and Klara Maresova
Children 2023, 10(4), 723; https://doi.org/10.3390/children10040723 - 14 Apr 2023
Viewed by 2244
Abstract
Our study evaluates the sensitivity of papilledema as a sign of high intracranial pressure in children. Patients younger than 18 years old, diagnosed with increased ICP, and who had received dilated fundus examination between 2019 and 2021 were retrospectively reviewed. Factors including the [...] Read more.
Our study evaluates the sensitivity of papilledema as a sign of high intracranial pressure in children. Patients younger than 18 years old, diagnosed with increased ICP, and who had received dilated fundus examination between 2019 and 2021 were retrospectively reviewed. Factors including the patient’s age, sex, aetiology, duration of signs or symptoms, intracranial pressure (ICP), and presence of papilledema were evaluated. We included 39 patients in this study, whose mean age was 6.7 years. The 31 patients without papilledema had a mean age of 5.7 years, and 8 patients (20%) with papilledema had a mean age of 10.4 (p < 0.037). The mean duration of signs or symptoms was nine weeks in patients without papilledema and seven weeks in those with papilledema (p = 0.410). The leading causes of increased ICP with papilledema were supratentorial tumor (12.5%), infratentorial tumor (33.3%), and hydrocephalus (20%) (p = 0.479). Papilledema was statistically significantly more common in older patients. We found no statistical significance between sex, diagnosis, and symptoms. The relatively low incidence of papilledema (20%) in our study shows that papilledema’s absence does not ensure the absence of increased ICP, especially in younger patients. Full article
(This article belongs to the Special Issue Management of Hydrocephalus in Children)
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